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808
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ShareScore release 0.9.0
Dataset results
808 results for “Dogs”
Integrated mapping of the dog epigenome
GEO Series GSE203107. Canis lupus familiaris. 186 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Methylation profiling by high throughput sequencing.
Gut health in multiple joint osteoarthritis: a multimodal investigation in humans and pet dogs
GEO Series GSE293105. Canis lupus familiaris. 94 samples. Type: Other.
Development of an exosomal gene signature to detect residual disease in dogs with osteosarcoma using a novel xenograft platform and machine learning
GEO Series GSE183191. Canis lupus familiaris; Mus musculus. 28 samples. Type: Expression profiling by high throughput sequencing.
Expression data from uninephrectomized dogs compared to sham operated dogs
GEO Series GSE47876. Canis lupus familiaris; Canis lupus. 20 samples. Type: Expression profiling by array.
Congestive heart failure in dog
GEO Series GSE472. Homo sapiens; Canis lupus familiaris. 5 samples. Type: Expression profiling by array.
Subcutaneous and gonadal adipose tissue transcriptome differences in lean and obese female dogs
GEO Series GSE29280. Canis lupus familiaris. 18 samples. Type: Expression profiling by array.
Dog visual perception of faces, objects and phase-scrambled images, measured with non-invasive electroencephalography
<p>This is the dataset used in the publication of Kujala MV, Kauppi J-P, Törnqvist H, Helle L, Vainio O, Kujala J, Parkkonen L (2020). Time-resolved classification of dog brain signals reveals early processing of faces, species and emotion. Scientific reports 10, 19846 (2020). https://doi.org/10.1038/s41598-020-76806-8.</p> <p>The dataset is electroencephalography data, measured non-invasively from the surface of the head from eight different dogs; and its supporting files. The data has been measured with 7-9 EEG electrodes; only the data from 7 EEG channels were used in the analysis. During the measurement, dogs were free to move; they were not restrained in any way. Instead, they were trained with positive operant conditioning to lie down and lean their head on a chin rest for short periods of time, during which they were shown still images from a computer screen. The stimuli were shown, in pseudo-randomized order, in eight different presentation scenarios, within 5 separate stimulus blocks per scenario, 15–20 stimuli per block. Between the stimulus blocks, dogs were always rewarded with a treat; this has caused major movement artifacts on the data between the stimulus blocks. Different presentation scenarios were shown in different days and repeated twice. Please refer to the above publication for further details of the experiment.</p> <p>The trigger is the same across all the stimuli; thus, separate scenario stimulus identifier lists were used in determining the stimulus order; please refer to the README.txt file and PresentationScenarios.xlsx files for further details.</p> <p>The dataset also contains anatomical magnetic resonance images of one dog, which was used in the aforementioned publication for source localization.</p> <p>If you have further questions regarding the data or the acquisition, please do not hesitate to contact the authors of the original publication.</p>
Dataset related to article "A Target Animal Effectiveness Study on Adjuvant Peptide-Based Vaccination in Dogs with Non-Metastatic Appendicular Osteosarcoma Undergoing Amputation and Chemotherapy "
<p>This record contains raw data related to article “A Target Animal Effectiveness Study on Adjuvant Peptide-Based Vaccination in Dogs with Non-Metastatic Appendicular Osteosarcoma Undergoing Amputation and Chemotherapy"</p> <p>Despite efforts to develop novel treatment strategies, human and canine osteosarcomas continue to have poor prognosis and limited overall survival. The aim of this clinical trial was to test the antitumor effect and safety of multiple dermal administrations of a peptide-based anticancer vaccine in dogs with non-metastatic appendicular osteosarcoma undergoing standard of care (SOC), consisting of limb amputation and adjuvant chemotherapy. Salmonella-infected canine osteosarcoma cells were induced to release immunogenic peptides in the extracellular space via Cx43 hemichannels opening; the secretome was collected and constituted the vaccine. Dogs with non-metastatic appendicular osteosarcoma were eligible for recruitment. Following limb amputation and adjuvant carboplatin, dogs were vaccinated on a monthly basis for six times and followed up with serial thoracic radiographs. A population of dogs undergoing SOC treatment (amputation and adjuvant carboplatin) before the vaccine was available served as controls. Primary endpoints were time to metastasis (TTM) and tumor-specific survival (TSS). Secondary endpoints were feasibility, toxicity, T-cell and humoral immune responses. A total of 20 dogs were vaccinated along with SOC and 34 received SOC only. Vaccine-specific humoral and T-cell responses were observed; their amplitude correlated with TSS. Vaccine-associated toxicity was not recorded. TTM and TSS were significantly longer in vaccinated versus unvaccinated dogs (TTM: 308 vs. 240 days, respectively; <em>p</em> = 0.010; TSS: 621 vs. 278 days, respectively; <em>p</em> = 0.002). In dogs with non-metastatic osteosarcoma undergoing SOC, the addition of a bacteria-based vaccination strategy increased TTM, thereby prolonging survival, while maintaining a safe profile. Additionally, vaccinated dogs developed a long-term tumor-specific response, as documented by the immunomonitoring of these patients over time. These results hold promise for future management of canine osteosarcoma</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.