Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
1,580
datasets available to search
ShareScore release 0.9.0
Dataset results
1,580 results for “vulnerability”
CALR-mutated cells are vulnerable to combined inhibition of the proteasome and the endoplasmic reticulum stress response
GEO Series GSE207684. Mus musculus. 7 samples. Type: Expression profiling by high throughput sequencing.
Metabolic reprogramming driven by TFE3 fusions unveils novel vulnerabilities in translocation renal cell carcinoma [RNA-Seq]
GEO Series GSE266517. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
Genome-wide synthetic lethal screen unveils novel CAIX – NFS1/xCT axis as a targetable vulnerability in hypoxic solid tumors.
GEO Series GSE167481. Homo sapiens. 8 samples. Type: Other.
Mechanistic study of Wee1 kinase inhibition with AZD1775 exposes drug targetable vulnerabilities in acute B-lymphoblastic leukemia [scRNA-seq]
GEO Series GSE218621. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.
Targeting the metabolic vulnerability of acute myeloid leukemia blasts with a combination of venetoclax and 8-chloro-adenosine
GEO Series GSE171552. Homo sapiens. 48 samples. Type: Expression profiling by high throughput sequencing.
A humanized Animal Model Predicts Clonal Evolution and Therapeutic Vulnerabilities in Myeloproliferative Neoplasms
GEO Series GSE160927. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
ATR represents a therapeutic vulnerability in clear cell renal cell carcinoma
GEO Series GSE211466. Mus musculus; Homo sapiens. 14 samples. Type: Expression profiling by high throughput sequencing.
The AhR-SRC axis as a therapeutic vulnerability in BRAFi-resistant melanoma
GEO Series GSE166617. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
Vulnerability of Purkinje cells induced from spinocerebellar ataxia type 6 patient-derived iPS cells
GEO Series GSE85349. Homo sapiens. 21 samples. Type: Expression profiling by array.
Single-cell RNA-seq reveals intratumoral heterogeneity in primary uveal melanomas and discloses new targetable vulnerability
GEO Series GSE138433. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Brain tumor stem cell dependence on glutaminase reveals a metabolic vulnerability through the amino acid deprivation response pathway
GEO Series GSE155300. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Transient splicing inhibition causes persistent DNA damage and enhances chemotherapy vulnerability in homologous recombination proficient triple-negative breast cancer
GEO Series GSE271749. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Hotspot mutations induce metabolic reprogramming and vulnerability to serine deprivation
GEO Series GSE134475. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Multimodal single-cell profiling reveals neuronal vulnerability and pathological cell states in focal cortical dysplasia
GEO Series GSE268807. Homo sapiens. 22 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
The PRMT5-splicing axis is a critical oncogenic vulnerability that regulates detained intron splicing
GEO Series GSE294247. Homo sapiens; Mus musculus. 110 samples. Type: Expression profiling by high throughput sequencing.
Loss of SMARCB1 evokes targetable epigenetic vulnerabilities in Epithelioid Sarcoma [ATAC-Seq]
GEO Series GSE281434. Homo sapiens. 24 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Translational profiling of neuronal subtypes reveals early vulnerability of somatostatin-expressing neurons in pre-symptomatic fatal familial insomnia
GEO Series GSE198063. Mus musculus. 159 samples. Type: Expression profiling by high throughput sequencing.
Identification of targetable vulnerabilities of PLK1-overexpressing cancers by synthetic dosage lethality [Microarray]
GEO Series GSE203237. Homo sapiens. 13 samples. Type: Other.
Cell cycle regulator MYBL2 is a distinct vulnerability in acute myeloid leukemia
GEO Series GSE305485. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Metabolic adaptations underlie epigenetic vulnerabilities in chemoresistant breast cancer. [RNA-Seq1]
GEO Series GSE111920. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.