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830 results for “Tumor Microenvironment”
Single-cell Multi-omics Analysis of Human Testicular Germ Cell Tumor Reveals its Molecular Features and Microenvironment II
GEO Series GSE229823. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.
Dataset related to article "Contrast Administration Impacts CT-Based Radiomics of Colorectal Liver Metastases and Non-Tumoral Liver Parenchyma Revealing the "Radiological" Tumour Microenvironment"
<p>This record contains raw data related to article "Contrast Administration Impacts CT-Based Radiomics of Colorectal Liver Metastases and Non-Tumoral Liver Parenchyma Revealing the "Radiological" Tumour Microenvironment"</p> <p> </p> <p>The impact of the contrast medium on the radiomic textural features (TF) extracted from the CT scan is unclear. We investigated the modification of TFs of colorectal liver metastases (CLM), peritumoral tissue, and liver parenchyma. One hundred and sixty-two patients with 409 CLMs undergoing resection (2017-2020) into a single institution were considered. We analyzed the following volumes of interest (VOIs): The CLM (Tumor-VOI); a 5-mm parenchyma rim around the CLM (Margin-VOI); and a 2-mL sample of parenchyma distant from CLM (Liver-VOI). Forty-five TFs were extracted from each VOI (LIFEx<sup>®®</sup>). Contrast enhancement affected most TFs of the Tumor-VOI (71%) and Margin-VOI (62%), and part of those of the Liver-VOI (44%, <em>p</em> = 0.010). After contrast administration, entropy increased and energy decreased in the Tumor-VOI (0.93 ± 0.10 vs. 0.85 ± 0.14 in pre-contrast; 0.14 ± 0.03 vs. 0.18 ± 0.04, <em>p</em> < 0.001) and Margin-VOI (0.89 ± 0.11 vs. 0.85 ± 0.12; 0.16 ± 0.04 vs. 0.18 ± 0.04, <em>p</em> < 0.001), while remaining stable in the Liver-VOI. Comparing the VOIs, pre-contrast Tumor and Margin-VOI had similar entropy and energy (0.85/0.18 for both), while Liver-VOI had lower values (0.76/0.21, <em>p</em> < 0.001). In the portal phase, a gradient was observed (entropy: Tumor > Margin > Liver; energy: Tumor < Margin < Liver, <em>p</em> < 0.001). Contrast enhancement affected TFs of CLM, while it did not modify entropy and energy of parenchyma. TFs of the peritumoral tissue had modifications similar to the Tumor-VOI despite its radiological aspect being equal to non-tumoral parenchyma.</p>
Mapping of cell types in the tumor microenvironment from tissue images via deep learning trained by spatial transcriptomics of lung adenocarcinoma
<p>Spatial transcriptomic data (10X Visium Platform) of lung adenocarcinoma that comprised thousands of spots with gene expression data and spatially registered H&E-stained tissue images from 22 samples.</p>
Sin3B loss enhances the T-cell inflamed tumor microenvironment through the redistribution of H3K27Ac signals in pancreatic cancer [CUT&Tag]
GEO Series GSE254767. Mus musculus. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
NR4A1 transcriptionally regulates the differentiation of stem-like CD8+ T cells in the tumor microenvironment (RNA-Seq)
GEO Series GSE266287. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
Cancer-associated fibroblast-like tumor cells remodel the Ewing sarcoma tumor microenvironment
GEO Series GSE236289. Homo sapiens. 28 samples. Type: Expression profiling by high throughput sequencing; Other.
A tumor microenvironment-driven network regulated by STAT3 and p65 controls the enrichment of cancer stem cells in human HR+/HER2- breast cancer cells
GEO Series GSE226339. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
NFAT5 induction by the tumor microenvironment enforces CD8 T cell exhaustion (CUT&Tag)
GEO Series GSE237313. Mus musculus. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Sin3B loss enhances the T-cell inflamed tumor microenvironment through the redistribution of H3K27Ac signals in pancreatic cancer [RNA-seq]
GEO Series GSE254770. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
The processed data of a landscape of immune microenvironment for Solid Tumors
<h3>This study provides a comprehensive and detailed atlas of the immune microenvironment for solid tumors. The dataset includes processed single-cell sequencing data from 25 types of solid tumors and 3 normal tissues.</h3>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.