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1,052
datasets available to search
ShareScore release 0.9.0
Dataset results
1,052 results for “cardiomyocytes”
Delayed Cardiomyocyte Response to Total Body Particle Radiation Exposure – Identification of Regulatory Gene Network [iron]
GEO Series GSE68874. Mus musculus. 15 samples. Type: Expression profiling by array.
Gene expression of cardiomyocytes exposed to L-lactate
GEO Series GSE153938. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Expression data from Ad-atrogin-1-GFP or Ad-GFP infected cardiomyocytes
GEO Series GSE31117. Rattus norvegicus. 4 samples. Type: Expression profiling by array.
Genome-Wide DNA Methylation Profiling of the Failing Human Heart with Mechanical Unloading Identifies LINC00881 as an Essential Regulator of Calcium Handling in the Cardiomyocyte
GEO Series GSE197672. Homo sapiens. 67 samples. Type: Expression profiling by high throughput sequencing; Methylation profiling by genome tiling array.
A temporal transcriptome and methylome in human embryonic stem cell-derived cardiomyocytes identifies novel regulators of early cardiac development
GEO Series GSE120547. Homo sapiens. 4 samples. Type: Methylation profiling by high throughput sequencing.
Stem Cells Secrete Factors That Induce Proliferation In Differentiated Cardiomyocytes
GEO Series GSE13708. Rattus norvegicus. 18 samples. Type: Expression profiling by array.
Expression profiles of the G protein-coupled estrogen receptor (GPER)-knockout versus intact cardiomyocytes
GEO Series GSE86843. Mus musculus. 16 samples. Type: Expression profiling by array.
Regulation of cardiomyocyte hypertrophy through dynamic regulation of type I collagen
GEO Series GSE204724. Mus musculus. 6 samples. Type: Expression profiling by array.
Delayed Cardiomyocyte Response to Total Body Particle Radiation Exposure - Identification of Regulatory Gene Network [iron]
We examined molecular responses using transcriptome profiling in isolated left ventricular murine cardiomyocytes to 90 cGy, 1 GeV proton (1H) and 15 cGy, 1 GeV/nucleon (n) iron (56Fe) particles 1, 3, 7, 14 and 28 days after exposure. Unsupervised clustering analysis of gene expression segregated samples according to the radiation (IR) response, and time after exposure with 56Fe-IR showing the greatest level of gene modulation. 1H-IR exposures showed little differential transcript modulation. Network analysis categorized the major differentially expressed genes into cell cycle, oxidative responses and transcriptional regulation functional groups. Transcriptional networks identified key nodes regulating expression. Individual transcription factors were inferred to be active at 1, 3, 7, 14 and 28 days after exposure. Validation of the signal transduction network by protein analysis showed that particle IR clearly regulates a long lived signaling mechanism for p38 MAPK signaling and NFATc4 activation. Electrophoresis mobility shift assays supported the role of additional key transcription factors GATA-4, STAT-3 and NF-kB as regulators of the response at specific time points. These data suggest that the molecular response to 56Fe-IR is unique and shows long-lasting gene expression in cardiomyocytes, up to 28 days after exposure. Additionally, proteins involved in signal transduction and transcriptional activation via DNA binding play a role in the response to high charge (Z) and energy (E) particles (HZE). Our study may have implications for NASA's efforts to develop heart disease risk estimates for astronauts safety via identification of specific HZE-IR molecular markers and for patients receiving conventional and particle radiotherapy. Transcriptome profiling in isolated left ventricular murine cardiomyocytes to 90 cGy, 1 GeV proton (1H) and 15 cGy, 1 GeV/nucleon (n) iron (56Fe) particles 1, 3, 7, 14 and 28 days after exposure.
Delayed Cardiomyocyte Response to Total Body Particle Radiation Exposure - Identification of Regulatory Gene Network [proton]
We examined molecular responses using transcriptome profiling in isolated left ventricular murine cardiomyocytes to 90 cGy, 1 GeV proton (1H) and 15 cGy, 1 GeV/nucleon (n) proton (56Fe) particles 1, 3, 7, 14 and 28 days after exposure. Unsupervised clustering analysis of gene expression segregated samples according to the radiation (IR) response, and time after exposure with 56Fe-IR showing the greatest level of gene modulation. 1H-IR exposures showed little differential transcript modulation. Network analysis categorized the major differentially expressed genes into cell cycle, oxidative responses and transcriptional regulation functional groups. Transcriptional networks identified key nodes regulating expression. Individual transcription factors were inferred to be active at 1, 3, 7, 14 and 28 days after exposure. Validation of the signal transduction network by protein analysis showed that particle IR clearly regulates a long lived signaling mechanism for p38 MAPK signaling and NFATc4 activation. Electrophoresis mobility shift assays supported the role of additional key transcription factors GATA-4, STAT-3 and NF-kB as regulators of the response at specific time points. These data suggest that the molecular response to 56Fe-IR is unique and shows long-lasting gene expression in cardiomyocytes, up to 28 days after exposure. Additionally, proteins involved in signal transduction and transcriptional activation via DNA binding play a role in the response to high charge (Z) and energy (E) particles (HZE). Our study may have implications for NASA's efforts to develop heart disease risk estimates for astronauts safety via identification of specific HZE-IR molecular markers and for patients receiving conventional and particle radiotherapy. Transcriptome profiling in isolated left ventricular murine cardiomyocytes to 90 cGy, 1 GeV proton (1H) and 15 cGy, 1 GeV/nucleon (n) proton (56Fe) particles 1, 3, 7, 14 and 28 days after exposure.
RNA-Seq of human induced pluripotent stem cell-derived cardiomyocytes from a cardiomyopathy patient and familial control
GEO Series GSE121559. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Rat cardiomyocyte: control vs diclofenac treatment
GEO Series GSE77880. Rattus norvegicus. 20 samples. Type: Expression profiling by array.
Transcriptome changes in human PSC-derived cardiomyocytes induced by doxorubicin II
GEO Series GSE255505. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
RNA-Seq of Ctrl, Myocd KO, Mrtfa/b DKO and TKO cardiomyocytes
GEO Series GSE210085. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
Infiltrating Monocytes Drive Cardiac Dysfunction in a Cardiomyocyte-Restricted Model of SARS-CoV-2 Infection
GEO Series GSE239372. Mus musculus. 19 samples. Type: Expression profiling by high throughput sequencing.
Differential transcriptional responses to cardiomyocyte-specific Notch activation in right versus left atria of murine cardiac tissue
GEO Series GSE138253. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Notch Activation Commits Mesoderm Cells to the Cardiac Lineage [cardiomyocytes]
GEO Series GSE143227. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.
Anthracyclines induce global changes in chromatin accessibility in cardiomyocytes that overlap with cardiovascular disease loci [CUT&Tag]
GEO Series GSE291262. Homo sapiens. 25 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Gene expression and chromatin organization changes in lamin A/C haploinsufficient human induced pluripotent stem cell-derived cardiomyocytes [Hi-C]
GEO Series GSE126459. Homo sapiens. 6 samples. Type: Other.
ERRBS of WT and TET TKO cells from stem cell (SC) to cardiomyocyte (CM)
GEO Series GSE186846. Homo sapiens. 7 samples. Type: Methylation profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.