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1,580 results for “vulnerability”

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geo24/100

Molecular characterization of selectively vulnerable neurons in Alzheimer’s Disease

GEO Series GSE147528. Homo sapiens. 20 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenApr 2020View details →
geo24/100

CDK12 Loss Promotes Prostate Cancer Development While Exposing Vulnerabilities to Paralog-Based Synthetic Lethality [scRNA-Seq]

GEO Series GSE254387. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenApr 2024View details →
geo24/100

Genetic screens reveal new targetable vulnerabilities in BAP1-deficient Mesothelioma

GEO Series GSE222376. Homo sapiens; Mus musculus. 21 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2023View details →
geo24/100

MicroRNA (miR)-211 loss promotes metabolic vulnerability and BRAF inhibitor sensitivity in melanoma

GEO Series GSE109378. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2019View details →
geo24/100

Serine biosynthesis is a metabolic vulnerability in FLT3-ITD-driven acute myeloid leukaemia [MV411_OCI-AML3_DMSO_AC220_24hr]

GEO Series GSE163930. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2021View details →
geo24/100

Polygenic architecture informs potential vulnerability to drug-induced liver injury

GEO Series GSE152447. Homo sapiens. 44 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2020View details →
geo24/100

CDK12 promotes tumorigenesis but induces vulnerability to therapies inhibiting folate one-carbon metabolism in breast cancer.

GEO Series GSE189274. Mus musculus; Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2022View details →
geo24/100

EPIKOL, a chromatin-focused CRISPR/Cas9-based screening platform to identify cancer-specific epigenetic vulnerabilities

GEO Series GSE173892. Homo sapiens; synthetic construct. 64 samples. Type: Other; Expression profiling by high throughput sequencing.

openGEO-OpenAug 2022View details →
geo24/100

Small molecule screen identifies de novo nucleotide synthesis as a vulnerability of cells lacking SIRT3

GEO Series GSE109279. Mus musculus. 5 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2018View details →
geo24/100

Pyruvate Anaplerosis is a Targetable Vulnerability in Persistent Leukaemic Stem Cells

GEO Series GSE216837. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJun 2023View details →
geo24/100

Transcriptomic atlas of midbrain dopamine neurons uncovers differential vulnerability in a Parkinsonism lesion model

GEO Series GSE233866. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2023View details →
geo24/100

Cross-species comparison reveals therapeutic vulnerabilities halting glioblastoma progression

GEO Series GSE240676. Homo sapiens; Mus musculus. 1579 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2023View details →
geo24/100

Combined TP53 and RB1 Loss Promotes Prostate Cancer Resistance to a Broad Spectrum of Cancer Therapeutics and Confers Vulnerability to Replication Stress

GEO Series GSE147250. Homo sapiens. 162 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJun 2020View details →
geo24/100

Pyrvinium pamoate targets to multiple vulnerabilities of Merkel cell carcinoma

GEO Series GSE229701. Homo sapiens. 30 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2023View details →
geo24/100

Mechanistic study of Wee1 kinase inhibition with AZD1775 exposes drug targetable vulnerabilities in acute B-lymphoblastic leukemia [scRNA-seq PDX MLL-7]

GEO Series GSE220476. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMay 2023View details →
geo24/100

C/EBPα confers dependence to fatty acid anabolic pathways and vulnerability to lipid oxidative stress-induced ferroptosis in FLT3-mutant leukemia [MOLM14_shCEBPA+DOX]

GEO Series GSE226457. Homo sapiens. 6 samples. Type: Expression profiling by array.

openGEO-OpenApr 2023View details →
geo24/100

High-throughput Fitness Experiments Reveal Specific Vulnerabilities of Human-Adapted Salmonella During Stress and Infection- Barseq9 (LB, gentamycin, cotrimoxazole, rifampicin, polymyxin B)

GEO Series GSE262848. Salmonella enterica subsp. enterica serovar Typhimurium str. D23580; Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150; Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74; Salmonella enterica subsp. enterica serovar Typhi str. Ty2. 48 samples. Type: Other.

openGEO-OpenApr 2024View details →
geo24/100

Polyamine Dysregulation Contributes to Muscle Fibers Vulnerability in ALS

GEO Series GSE271011. Mus musculus. 7 samples. Type: Other.

openGEO-OpenJan 2025View details →
geo24/100

Pervasive H3K27 acetylation leads to ERV expression and a therapeutic vulnerability in H3K27M gliomas [ChIP-Seq]

GEO Series GSE129135. Homo sapiens. 80 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenMay 2019View details →
geo24/100

Pharmacogenomic synthetic lethal screens reveal hidden vulnerabilities and new therapeutic approaches for treatment of NF1-associated tumor

GEO Series GSE262030. Homo sapiens. 51 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMar 2024View details →

ScienceDex guides

Understand access before you commit

These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

Compare curated datasets

Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record