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14,866 results for “cancer cell”
Fig. 5 in Triterpenoids from Liquidambar Fructus induced cell apoptosis via a PI3KAKT related signal pathway in SMMC7721 cancer cells
Fig. 5. Induction of apoptosis by compounds 5, 7 and 8 in SMMC7721 cancer cells at 36 h *P <0.05 vs control.
Fig. 9 in Triterpenoids from Liquidambar Fructus induced cell apoptosis via a PI3KAKT related signal pathway in SMMC7721 cancer cells
Fig. 9. Expression changes of PI3K-AKT signal pathway related genes. (A) Representative Western blot results of compounds 5, 7 and 8 inducing expression changes of PI3K-AKT signal pathway related proteins in SMMC7721 cells; (B) Statistical analysis of protein expression levels in (A). The results shown were representative of three independent experiments. *P <0.05 vs control.
Fig. 8 in Triterpenoids from Liquidambar Fructus induced cell apoptosis via a PI3KAKT related signal pathway in SMMC7721 cancer cells
Fig. 8. Effects of compounds 5, 7 and 8 on expression of PI3K-AKT pathway related genes on SMMC7721 cell. The RT-qPCR results shown were representative of three independent experiments. *P <0.05 vs control.
Fig. 2 in Synthesis of bilocularin A carbamate derivatives and their evaluation as leucine transport inhibitors in prostate cancer cells
Fig. 2. COSY (in green) and key HMBC (in red) correlations of compound 2. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Fig. 4 in Synthesis of bilocularin A carbamate derivatives and their evaluation as leucine transport inhibitors in prostate cancer cells
Fig. 4. Effects of compounds 1–9 on cell viability and leucine uptake in LNCaP cells (a) MTT cell growth assay was performed in LNCaP cells treated with compounds 1–9 at 20 μM for 72 h (n = 3, mean ± SEM) (b) [3H]-L-leucine uptake was performed using 20 μM of compounds 1–9 in LNCaP cells (n = 3, mean ± SEM). Asterisks represent Pvalues: *P ⩽ 0.05; ***P ⩽ 0.001 for one-way analysis of variance by Dunnett's multiple comparison test (c) [3H]-L-leucine uptake was performed at varying doses of compounds 4 and 5 to determine the IC50 values (n = 3, mean ± SEM).
Fig. 3 in Synthesis of bilocularin A carbamate derivatives and their evaluation as leucine transport inhibitors in prostate cancer cells
Fig. 3. ORTEP of bilocularin A carbamate analogue 7; Hydrogen atoms, EtOH and H2O molecules are omitted for clarity.
Fig. 1. Derivatisation reaction conditions for bilocularin A in Synthesis of bilocularin A carbamate derivatives and their evaluation as leucine transport inhibitors in prostate cancer cells
Fig. 1. Derivatisation reaction conditions for bilocularin A (1) and the resulting semi-synthetic carbamate library (2–9).
Molecular Jackhammers Eradicate Cancer Cells by Vibronic-Driven-Action
<p>The source data collected and utilized during the study "Molecular jackhammers eradicate cancer cells by vibronic-driven-action" is provided here, to be publish in <em>Nature Chemistry </em>and available in preprint in <em>BioRxiv</em>. A new type of molecular mechanical action is described in this study. This is a plasmon in small organic molecules that induce a whole molecule vibration. These whole molecule vibrations are applied to destroy cellular membranes by mechanical action.</p> <p>The source data uploaded here are: Numerical data (.xlsx), flow cytometry source data (.wsp), and uncropped confocal microscopy images (.tiff). </p>
Elimination of PTV Margins Based on MRI-guided Adaptive Stereotactic Radiotherapy for Non-small Cell Lung Cancer With Brain Metastasis
ClinicalTrials.gov study NCT06582940. IPD Sharing: NO. Countries: 1. Publications: 8.
Tempus Sculptor Study: Small Cell Lung Cancer (SCLC) Observational Study
ClinicalTrials.gov study NCT05257551. IPD Sharing: Not stated. Countries: 1. Publications: 21.
Methylprednisolone After Split-course Chemoradiotherapy For Bulky Local Advanced None-small Cell Lung Cancer
ClinicalTrials.gov study NCT03661567. IPD Sharing: UNDECIDED. Countries: 1. Publications: 16.
Early Specialized Cardiovascular Intervention Based on Impedance Cardiography in Locally Advanced Non-small Cell Lung Cancer Patients
ClinicalTrials.gov study NCT04980716. IPD Sharing: Not stated. Countries: 1. Publications: 25.
Combination Chemotherapy With or Without Bevacizumab in Treating Patients With Advanced, Metastatic, or Recurrent Non-Small Cell Lung Cancer
ClinicalTrials.gov study NCT00021060. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Study of Pembrolizumab (MK-3475) vs Placebo for Participants With Non-small Cell Lung Cancer After Resection With or Without Standard Adjuvant Therapy (MK-3475-091/KEYNOTE-091)
ClinicalTrials.gov study NCT02504372. IPD Sharing: YES. Countries: 0. Publications: 1.
Chemoradiation and Endothelial Progenitor Cells in Colorectal Cancer
ClinicalTrials.gov study NCT00325871. IPD Sharing: NO. Countries: 1. Publications: 1.
Cetuximab After Immunotherapy for the Treatment of Head and Neck Squamous Cell Cancer
ClinicalTrials.gov study NCT04375384. IPD Sharing: NO. Countries: 1. Publications: 1.
Histocompatibility Leukocyte Antigen (HLA)-A*0201 Restricted Peptide Vaccine Therapy in Patients With Non-Small Cell Lung Cancer
ClinicalTrials.gov study NCT00673777. IPD Sharing: Not stated. Countries: 1. Publications: 6.
Efficacy/Safety of Imprime PGG® Injection With Bevacizumab and Paclitaxel/Carboplatin in Patients With Untreated Advanced Non-Small Cell Lung Cancer (NSCLC)
ClinicalTrials.gov study NCT00874107. IPD Sharing: Not stated. Countries: 2. Publications: 2.
VX-710, Doxorubicin, and Vincristine for the Treatment of Patients With Recurrent Small Cell Lung Cancer
ClinicalTrials.gov study NCT00003847. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Assessing the Suitability of an Imaging Probe for Use in Clinical Cell and Gene Therapy Trials in Cancer and Rheumatoid Arthritis
ClinicalTrials.gov study NCT00185848. IPD Sharing: Not stated. Countries: 1. Publications: 1.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.