Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
872
datasets available to search
ShareScore release 0.9.0
Dataset results
872 results for “disease progression”
Age-Related Development and Progression of Hypertension and Kidney Disease in Dahl SS/JrHsdMcwi Rats Maintained on a 0.4% NaCl Diet: Effects of Sex and Chromosome 1
GEO Series GSE203266. Rattus. 12 samples. Type: Expression profiling by high throughput sequencing.
Combination of multiomics approach and BCR-ABL based molecular testing: A better way to monitor treatment regimen and disease progression in Chronic Myeloid Leukemia
GEO Series GSE77573. Homo sapiens. 79 samples. Type: Expression profiling by array; Genome variation profiling by SNP array.
NSD2 aggravates metabolic dysfunction-associated steatotic liver disease progression by suppressing TFEB-mediated autophagy-lysosomal pathway
GEO Series GSE287554. Homo sapiens. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Immunopathogenesis of renal inflammation during the progression, remission and relapse of renal disease in the NZB/W murine lupus model
GEO Series GSE50038. Mus musculus. 100 samples. Type: Expression profiling by array.
Age-related blood transcriptional regulators affect disease progression in pediatric multiple sclerosis
GEO Series GSE203241. Homo sapiens. 59 samples. Type: Expression profiling by array.
Transcriptome profiling of 13 HIV positive individuals of variable disease progression from an Indian Cohort
GEO Series GSE200462. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Combination of multiomics approach and BCR-ABL based molecular testing: A better way to monitor treatment regimen and disease progression in Chronic Myeloid Leukemia [OncoScan]
GEO Series GSE77571. Homo sapiens. 39 samples. Type: Genome variation profiling by SNP array.
Combination of multiomics approach and BCR-ABL based molecular testing: A better way to monitor treatment regimen and disease progression in Chronic Myeloid Leukemia [HTA-2_0]
GEO Series GSE77191. Homo sapiens. 40 samples. Type: Expression profiling by array.
Data set from the article Vianello E, Marrocco-Trischitta Massimiliano M, Dozio E, Bandera F, Tacchini L, Canciani E, Dellavia C, Schmitz G, Lorenzo M, Corsi Romanelli Massimiliano M. Correlational study on altered epicardial adipose tissue as a stratification risk factor for valve disease progression through IL-13 signaling. J Mol Cell Cardiol. 2019 Jul;132:210-218. doi: 10.1016/j.yjmcc.2019.05.012. Epub 2019 May 15. Erratum in: J Mol Cell Cardiol. 2019 Aug;133:112. PMID: 31102584.
<p>Data set from the article Vianello E, Marrocco-Trischitta Massimiliano M, Dozio E, Bandera F, Tacchini L, Canciani E, Dellavia C, Schmitz G, Lorenzo M, Corsi Romanelli Massimiliano M. Correlational study on altered epicardial adipose tissue as a stratification risk factor for valve disease progression through IL-13 signaling. J Mol Cell Cardiol. 2019 Jul;132:210-218. doi: 10.1016/j.yjmcc.2019.05.012. Epub 2019 May 15. Erratum in: J Mol Cell Cardiol. 2019 Aug;133:112. PMID: 31102584.</p> <p>This is the abstract:</p> <p><strong>Aims: </strong>Genetic and environmental factors all interact in the risk of progression of valvular dysfunctions. Previous studies reported a relation between valve diseases and epicardial adipose tissue (EAT) thickness. The aim of this study was to verify the possible relationship between the molecular pattern of EAT related to IL-13 fibrogenic cytokine expression and valve dysfunction.</p> <p><strong>Methods and results: </strong>A valvular heart disease (VHD) population was stratified according to their median EAT thickness (7 mm). The molecular expression of IL-13 in EAT is directly related to the molecular expression of genes associated with extracellular matrix (ECM) turnover, macrophage infiltration and promotion of the formation of ectopic calcific nodules involved in aorta coarctation and calcification.</p> <p><strong>Conclusion: </strong>IL-13 gene expression in altered EAT is directly related to the expression of genes involved in ECM turnover and the formation of ectopic calcific nodules, suggesting measurements of EAT as a stratification risk factor for valve instability in the VHD patients.</p> <p> </p>
Dataset related to the article "Diagnostic accuracy of subendocardial vs. transmural myocardial perfusion defect for the detection of in-stent restenosis or progression of coronary artery disease after percutaneous coronary intervention
<p>This record contains raw datarelated to the article"Diagnostic accuracy of subendocardial vs. transmural myocardial perfusion defect for the detection of in-stent restenosis or progression of coronary artery disease after percutaneous coronary intervention</p> <p> </p> <p>Background. The ADVANTAGE study demonstrated in a cohort of stented patients a diagnostic accuracy of stress myocardial CT perfusion (CTP) significantly higher than that of coronary CT angiography (CCTA) for the detection of in-stent restenosis (ISR) or CAD progression vs. quantitative coronary angiography (QCA). This is a pre-defined subanalysis of the ADVANTAGE aimed at assessing the difference in terms of diagnostic accuracy vs. QCA of a subendocardial vs. a transmural perfusion defect using static stress CTP.<br> Methods. We enrolled consecutive patients who previously underwent coronary stenting and were referred for QCA. All patients underwent stress CTP and rest CTP+CCTA. The diagnostic accuracy of CCTA and CTP were evaluated in territory-based and patient-based analyses. We compared the diagnostic accuracy of “subendocardial” perfusion defect, defined as hypo-enhancement encompassing >25% but <50% of the transmural myocardial thickness within a specific coronary territory vs. “transmural” perfusion defect, defined as hypo-enhancement encompassing >50% of the transmural thickness.<br> Results. In 150 patients (132 men, mean age 65.1±9.1 years), the diagnostic accuracy of subendocardial vs. transmural perfusion defect in a vessel-based analysis was 93.5% vs. 87.7%, respectively (p<0.0001). The sensitivity and specificity of subendocardial vs. transmural defect were 87.9% vs. 46.9% (p<0.001) and 94.9% vs. 97.9% (p=0.004), respectively. In a patient-based analysis, the diagnostic accuracy of the subendocardial vs. transmural approach was 86.6% vs. 68% (p<0.0001).<br> Conclusions. This study shows that detection of a subendocardial perfusion defect as compared to a transmural defect is significantly more accurate to identify coronary territories with ISR or CAD progression.</p> <p> </p>
MicroRNA Profile in CD8+ T-lymphocytes from HIV-Infected Individuals: Relationship with Disease Progression
GEO Series GSE71650. synthetic construct; Homo sapiens. 136 samples. Type: Non-coding RNA profiling by array.
Distinct transcriptomic and epigenomic responses of mature oligodendrocytes during disease progression in a mouse model of multiple sclerosis [RNA-seq]
GEO Series GSE283086. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.