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1,079 results for “source data”
Source Data for "Forced and spontaneous symmetry breaking in cell polarization."
<p>Source Data for Figures 2-4</p>
Noise2Fast, Figure 5 Source Data
<p>ND2 files represent a 20x FOV wide scan followed by a 60x zoom in on each detected mitosis.</p>
Source data for: Soluble MAC is primarily released from MAC-resistant bacteria that potently convert complement component C5
<p><span>The Membrane Attack Complex (MAC or C5b-9) is an important effector of the immune system to kill invading microbes. MAC is formed when complement enzymes on the bacterial surface convert complement component C5 into C5b. Although the MAC is a membrane-inserted complex, soluble forms of MAC (sMAC, or terminal complement complex (TCC)) are often detected in sera of patients suffering from infections. Consequently, sMAC has been proposed as a biomarker, but it remains unclear when and how it is formed during infections. Here, we studied mechanisms of MAC formation on different Gram-negative and Gram-positive bacteria and found that sMAC is primarily formed in human serum by bacteria resistant to MAC-dependent killing. Surprisingly, C5 was converted into C5b more potently by MAC-resistant compared to MAC-sensitive <em>Escherichia coli</em> strains. In addition, we found that MAC precursors are released from the surface of MAC-resistant bacteria during MAC assembly. Although the release of MAC precursors from bacteria induced lysis of bystander human erythrocytes, serum regulators vitronectin (Vn) and clusterin (Clu) can prevent this. Combining size exclusion chromatography with mass spectrometry profiling, we show that sMAC released from bacteria in serum is a heterogeneous mixture of complexes composed of C5b-8, up to 3 copies of C9 and multiple copies of Vn and Clu. Altogether, our data provide molecular insight into how sMAC is generated during bacterial infections. This fundamental knowledge could form the basis for exploring the use of sMAC as a biomarker.</span></p>
Data for: Evaluating potential sources of invasive wild pigs in Ontario
<p class="CxSpFirst">Invasive wild pigs (<i>Sus scrofa</i>) are considered one of the most damaging species globally, and once they become established in an area, they are notoriously difficult to eliminate. As such, identifying the potential pathways of invasion, especially in places with emerging populations, is critical for preventing new or continued invasion. Wild pigs have been reported in Ontario, Canada in recent years. We tested four non-exclusive hypotheses about the source of wild pigs in Ontario: 1) escapees from captive sources within Ontario; 2) invasion from neighboring jurisdictions; 3) existing wild populations within Ontario; and 4) translocation and illegal release. We found that sightings of Eurasian wild boar were closer to premises with wild boar than were random locations; wild boar sightings were an average of 16.3 km (SD = 25.4 km, min = 0.2 km, n = 20) from premises with wild boar. We also found that sightings of domestic pigs were closer to domestic pig farms than expected. Sightings of wild pigs in groups of more than four animals were rare. Our results suggest that wild pigs observed in Ontario are recent escapes from captivity, recognizing that there may be established groups of wild pigs that we have not yet detected. While not common, we also received reports indicating that in the past, wild pigs have been translocated and illegally released. Other North American jurisdictions that have been successful at eliminating wild pigs have removed existing populations and changed regulations to limit future invasion, such as prohibiting possession and transport of wild boar and prohibiting hunting of wild pigs.</p>
Source Data
<p>Source Data for Topál et al. (2022) "<strong>Discrepancies between observations and climate models of large-scale wind-driven Greenland melt influence sea-level rise projections</strong>" article published in Nature Communications (https://doi.org/10.1038/s41467-022-34414-2) containing the underlying data of the Figures from the main text.</p>
data source file to factors affecting augmented reality head mounted device performance in real OR
<p>Excel spread sheet of data generated durgin the experiments and later used for statistical analysis</p>
Supplementary Website, Data, and Scripts for the Paper "Hierarchical and Hybrid Organizational Structures in Open-Source Software Projects: A Longitudinal Study"
<p>Supplementary website containing result plots and data, anonymized raw data, and scripts used to produce the results of the paper "Hierarchical and Hybrid Organizational Structures in Open-Source Software Projects: A Longitudinal Study".</p>
Figure 2 from: Roma-Marzio F, Peruzzi L, Bedini G (2017) Personal private herbaria: a valuable but neglected source of floristic data. The case of Italian collections today. Italian Botanist 3: 7-15. https://doi.org/10.3897/italianbotanist.3.12097
Figure 2 - Stacked bar chart showing the relationship between the degree of pest problem and the treatments to prevent it in the Italian private herbaria.
Source data and codes for Canted spin order as a platform for ultrafast conversion of magnons
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dataset for Spatial Distribution of Wildlife on University Campuses and Its Correlations with Environmental Factors: A Multi-Source Data Analysis
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Source data for GEDI - part 2
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Source data for GEDI - part 1
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Source data for GEDI - part 4
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Source data for GEDI - part 3
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Source Data for: VCP/p97-Associated Proteins are Binders and Debranching Enzymes of K48-K63-Branched Ubiquitin Chains
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Predicting Protein Synergistic Effect in Arabidopsis using Epigenome Profiling (Data Source)
<p>Peak-calling data of QHistone Histone related 1,534 ChIP-seqs and protein 1,566 ChIP-seqs.</p> <p><strong>histone related chip seq:</strong> The folder contains bed file (narrowPeak) of 1,534 histone ChIP-seqs and corrosponding meta-data.</p> <p><strong>protein chip seqs: </strong>The folder contains bed file (narrowPeak) of 1,566 protein ChIP-seqs and corrosponding meta-data.</p>
SAT-based Decision Tree Learning for Large Data Sets - Results and Source code
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Source Data for the study of Sen1-dependent transcription termination
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Source data for "Optimizing 5'UTRs for mRNA-delivered gene editing using deep learning"
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Human Developing Retina Atlas (Source data)
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ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.