Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
1,274
datasets available to search
ShareScore release 0.9.0
Dataset results
1,274 results for “Disease Model”
Transcriptional profiling of cortex and striatal tissue following chronic dosing of PDE10A inhibitor PF-02545920 in a Q175 homozygous knock-in mouse model of Huntington’s disease
GEO Series GSE89505. Mus musculus. 90 samples. Type: Expression profiling by high throughput sequencing.
FLASH proton radiotherapy mitigates inflammatory and fibrotic pathways and preserves cardiac function in a preclinical mouse model of radiation-induced heart disease
GEO Series GSE261367. Mus musculus. 11 samples. Type: Expression profiling by high throughput sequencing.
Transcriptome profiling in knock-in mouse models of Huntington's disease [Striatum_miRNA]
GEO Series GSE78793. Mus musculus. 96 samples. Type: Expression profiling by high throughput sequencing.
Spatially-patterned and functional kidney assembloids recapitulate progenitor self-assembly and enable high-fidelity in vivo disease modeling
GEO Series GSE264516. Mus musculus. 34 samples. Type: Expression profiling by high throughput sequencing.
Whole genome transcriptome analysis identifies indices of fast and slow disease progression in two ALS mouse models
GEO Series GSE46298. Mus musculus. 64 samples. Type: Expression profiling by array.
Age-dependent changes in phosphorylation of signaling molecules in brain tissues of Alzheimer's disease (AD) model mice
GEO Series GSE55452. Mus musculus. 12 samples. Type: Protein profiling by protein array.
Thrombospondin-1 type 1 repeats in a model of inflammatory bowel disease: genetic profile and therapeutic effects
GEO Series GSE32697. Mus musculus. 28 samples. Type: Expression profiling by array.
Microglia Depletion Reduces Human Neuronal APOE4-Driven Pathologies in a Chimeric Alzheimer’s Disease Model
GEO Series GSE248020. Mus musculus. 5 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomics analysis of human iPSC-derived dopaminergic neurons reveals a novel model for sporadic Parkinson’s disease
GEO Series GSE196190. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
Gene expression profiles of E. coli in the gut of inflammatory bowel disease models.
GEO Series GSE303196. Escherichia coli BL21(DE3). 33 samples. Type: Other.
Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease
GEO Series GSE230707. synthetic construct; Homo sapiens; Mus musculus. 63 samples. Type: Expression profiling by high throughput sequencing; Other.
Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases
GEO Series GSE237000. Homo sapiens. 34 samples. Type: Expression profiling by high throughput sequencing.
Ctla-4 deficiency induces an inflammatory bowel disease-like phenotype in a zebrafish model [bulkRNA-seq]
GEO Series GSE255304. Danio rerio. 6 samples. Type: Expression profiling by high throughput sequencing.
The disease modeling of Jacob Syndrome reveals an aberrant genome-wide expression modulation from the Y chromosome [RNA-seq]
GEO Series GSE264395. Homo sapiens. 99 samples. Type: Expression profiling by high throughput sequencing.
Inhaled Xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy [Tdt Tomato - mice]
GEO Series GSE273541. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
Beta Amyloid toxicity in a Caenorhabditis elegans model of Alzheimer's disease
GEO Series GSE65851. Caenorhabditis elegans. 47 samples. Type: Expression profiling by array.
Transcriptomic Profiling of Circulating Tumor Cells in Multiple Myeloma: A New Model to Understand Disease Dissemination II
GEO Series GSE124436. Homo sapiens. 20 samples. Type: Expression profiling by array.
Human branching cholangiocyte organoids recapitulate embryogenic bile duct development and provide an unique model to study biliary diseases.
GEO Series GSE179601. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
A novel Menin-MLL inhibitor induces specific chromatin changes and eradicates disease in models of MLL-rearranged leukemia [Cut&Run]
GEO Series GSE137814. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Analysis of fatty liver disease development and progression in a combined mouse model of hedgehog signaling attenuation and diet-induced hepatic steatosis
GEO Series GSE94754. Mus musculus. 16 samples. Type: Expression profiling by array.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.