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1,580 results for “vulnerability”

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geo24/100

Cross-species comparison reveals therapeutic vulnerabilities halting glioblastoma progression

GEO Series GSE240675. Mus musculus; Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2023View details →
geo24/100

Senescence induced by BMI1 inhibition is a therapeutic vulnerability in H3K27M-mutant DIPG

GEO Series GSE140768. Homo sapiens. 30 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.

openGEO-OpenOct 2020View details →
geo24/100

C/EBPα confers dependence to fatty acid anabolic pathways and vulnerability to lipid oxidative stress-induced ferroptosis in FLT3-mutant leukemia [MOLM14_shCEBPAconstit]

GEO Series GSE226423. Homo sapiens. 6 samples. Type: Expression profiling by array.

openGEO-OpenApr 2023View details →
geo24/100

CDK12 Loss Promotes Prostate Cancer Development While Exposing Vulnerabilities to Paralog-Based Synthetic Lethality

GEO Series GSE254390. Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenApr 2024View details →
geo24/100

microRNA Induction of Fatal Differentiation Programs is a Context-selective Vulnerability in Ovarian Cancer Cells [miRNA]

GEO Series GSE67329. Homo sapiens. 7 samples. Type: Non-coding RNA profiling by array.

openGEO-OpenMar 2015View details →
geo24/100

Global Patterns of Gene Expression Associated with Vulnerability and Resilience to Social Defeat

GEO Series GSE8870. Mus musculus. 18 samples. Type: Expression profiling by array.

openGEO-OpenSep 2007View details →
geo24/100

A specific prelimbic-nucleus accumbens pathway controls resilience versus vulnerability to develop food addiction.

GEO Series GSE139482. Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2020View details →
geo24/100

Motivated cocaine seeking lead to transgenerational epigenetic inheritance of vulnerability to cocaine addiction

GEO Series GSE72401. Rattus norvegicus. 18 samples. Type: Methylation profiling by high throughput sequencing.

openGEO-OpenMar 2017View details →
geo24/100

Targeting PIKfyve-driven lipid homeostasis as a metabolic vulnerability in pancreatic cancer [ChIP-seq]

GEO Series GSE277830. Homo sapiens. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenFeb 2025View details →
geo24/100

Uncovering the rewired IAP-JAK regulatory axis as an immune-dependent vulnerability of LKB1-mutant lung cancer

GEO Series GSE273406. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2024View details →
geo24/100

PP2A inhibition instructs spliceosome phosphorylation patterns to create splicing vulnerability in colon adenocarcinoma

GEO Series GSE236625. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenApr 2024View details →
geo24/100

Super-enhancer-based identification of a BATF3/IL-2R-module reveals vulnerabilities in anaplastic large cell lymphoma [RNA-Seq]

GEO Series GSE158893. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJun 2021View details →
geo24/100

PHGDH Arginine Methylation by PRMT1 Promotes Serine Synthesis and Represents a Therapeutic Vulnerability in Hepatocellular Carcinoma

GEO Series GSE207435. Homo sapiens. 54 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJul 2022View details →
geo24/100

Transcriptomic analysis to identify genes associated with hypothalamus vulnerability in aging mice with cognitive decline

GEO Series GSE240365. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJul 2024View details →
geo24/100

Regulatory Enhancer Profiling of Mesenchymal-type Gastric Cancer Reveals Subtype-Specific Epigenomic Landscapes and Targetable Vulnerabilities

GEO Series GSE186521. Homo sapiens. 163 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenAug 2023View details →
geo24/100

CBX5 loss drives EGFR inhibitor resistance and results in therapeutically actionable vulnerabilities in lung cancer

GEO Series GSE114563. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2023View details →
geo24/100

Genome-wide CRISPR-Cas9 screen reveals selective vulnerability of ARID1A deficiency Hepatocellular Carcinoma

GEO Series GSE228177. Homo sapiens. 16 samples. Type: Other.

openGEO-OpenSep 2023View details →
geo24/100

Hepatitis C virus scarring of the epigenome and creates targetable vulnerabilities following viral clearance

GEO Series GSE168186. Homo sapiens. 83 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Methylation profiling by genome tiling array.

openGEO-OpenSep 2021View details →
geo24/100

The landscape of therapeutic vulnerabilities in EGFR inhibitor osimertinib drug tolerant persister cells [RNA-seq]

GEO Series GSE193258. Homo sapiens. 60 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenApr 2022View details →
geo24/100

AR-negative prostate cancer is vulnerable to loss of JMJD1C demethylase

GEO Series GSE166657. Homo sapiens. 27 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2021View details →

ScienceDex guides

Understand access before you commit

These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

Compare curated datasets

Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record