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1,274 results for “Disease Model”

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geo20/100

Genomic landscape of transcriptional and epigenetic dysregulation in a mouse model of early onset Huntington's disease

GEO Series GSE44855. Mus musculus. 24 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by array.

openGEO-OpenJun 2013View details →
geo20/100

REST and Neural Gene Network Dysregulation in iPS Cell Models of Alzheimer’s Disease (Affymetrix iPSC data set)

GEO Series GSE117584. Homo sapiens. 10 samples. Type: Expression profiling by array.

openGEO-OpenJan 2019View details →
geo20/100

FUS/TLS acts as an aggregation-dependent modifier of polyglutamine disease model mice

GEO Series GSE80109. Mus musculus. 24 samples. Type: Expression profiling by array.

openGEO-OpenFeb 2017View details →
geo20/100

Comparative profiling of hippocampal gene expression in AppNL-G-F knock-in mouse model of Alzheimer's disease.

GEO Series GSE157161. Mus musculus. 6 samples. Type: Expression profiling by array.

openGEO-OpenDec 2021View details →
geo20/100

Modelling G2019S-LRRK2 sporadic Parkinson’s disease in 3D midbrain organoids

GEO Series GSE125234. Homo sapiens. 4 samples. Type: Expression profiling by array.

openGEO-OpenFeb 2019View details →
geo20/100

Inhaled Xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy [Xenon PK in APP.PS1 Tcells - mice]

GEO Series GSE272801. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2025View details →
geo20/100

Developing a clinically relevant ovarian cancer model incorporating surgical cytoreduction to evaluate treatment of micro-metastatic disease

GEO Series GSE149320. Mus musculus. 6 samples. Type: Expression profiling by array.

openGEO-OpenApr 2020View details →
geo20/100

Expression analysis in yeast model of Huntington's disease (HD)

GEO Series GSE18644. Saccharomyces cerevisiae. 15 samples. Type: Expression profiling by array.

openGEO-OpenNov 2010View details →
geo20/100

Transcriptome profiling in knock-in mouse models of Huntington's disease (striatum_mRNA).

GEO Series GSE78274. Mus musculus. 96 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2016View details →
geo20/100

Rescue of alpha-synuclein toxicity in a yeast model of Parkinson's disease

GEO Series GSE11633. Saccharomyces cerevisiae. 93 samples. Type: Expression profiling by array.

openGEO-OpenJan 2010View details →
geo20/100

Multiplex three dimensional brain gene expression mapping in a mouse model of Parkinson's disease

GEO Series GSE30. Mus musculus. 80 samples. Type: Expression profiling by array.

openGEO-OpenMar 2002View details →
geo20/100

FUS/TLS acts as an aggregation-dependent modifier of polyglutamine disease model mice (II)

GEO Series GSE80093. Mus musculus. 12 samples. Type: Expression profiling by array.

openGEO-OpenFeb 2017View details →
geo20/100

Sex differences in cardiac aging in mice and development of a female murine model of hypertensive disease in the elderly: Study of the left atrial tissue

GEO Series GSE250053. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2023View details →
geo20/100

Inhaled Xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy [5xFAD-MITRG-iMGL 6M]

GEO Series GSE271472. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2025View details →
geo20/100

Transcriptional profiling of striatum from a mouse model of Huntington's disease (Q140) crossed with Msh3 heterozygous and homozygous mice [Msh3 snRNA-seq]

GEO Series GSE241278. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2025View details →
geo20/100

DNA methylation profiles from a transgenic sheep model of Huntington's disease

GEO Series GSE147003. Homo sapiens; Mus musculus; Ovis aries; Rattus norvegicus. 168 samples. Type: Methylation profiling by genome tiling array.

openGEO-OpenJul 2020View details →
geo20/100

Hippocampal gene expression profiling of a model of Alzheimer`s Disease upon treatment with the ACE inhibitor captopril

GEO Series GSE46871. Mus musculus. 6 samples. Type: Expression profiling by array.

openGEO-OpenMay 2013View details →
geo20/100

TLR7 agonism accelerates disease in a mouse model of primary Sjögren’s syndrome and drives expansion of age-associated B cells

GEO Series GSE212467. Mus musculus; synthetic construct. 64 samples. Type: Protein profiling by protein array.

openGEO-OpenSep 2022View details →
geo20/100

A novel Menin-MLL inhibitor induces specific chromatin changes and eradicates disease in models of MLL-rearranged leukemia

GEO Series GSE127508. Homo sapiens. 78 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenNov 2019View details →
geo20/100

Differential gene expression profiling in response to paraquat using a Drosophila Parkinson's disease model

GEO Series GSE135919. Drosophila melanogaster. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2019View details →

ScienceDex guides

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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

Compare curated datasets

Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record