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1,274 results for “Disease Model”

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geo20/100

Type I Interferon Signaling Mediates Microglial Dysfunction and Senescence in Human-Mouse Chimeric Brain Models of Down Syndrome and Alzheimer’s Disease [single-cell RNA-seq]

GEO Series GSE189226. Mus musculus; Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJul 2022View details →
geo20/100

Transcriptome profiling in knock-in mouse models of Huntington's disease (cortex_mRNA).

GEO Series GSE78272. Mus musculus. 95 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2016View details →
geo20/100

PIKFYVE Inhibition Mitigates Disease in Models of Diverse Forms of ALS [2]

GEO Series GSE221016. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2022View details →
geo20/100

A functional genomics predictive network model identifies regulators of inflammatory bowel disease: Microarray Analysis of Human Blood and Intestinal Biopsy Samples from a Phase 2b, Double-blind, Plac

GEO Series GSE100833. Homo sapiens. 1717 samples. Type: Expression profiling by array.

openGEO-OpenJul 2017View details →
geo20/100

The olfactory molecular snapshot in aged Tg2576 Alzheimer´s disease mouse model

GEO Series GSE103835. Mus musculus. 6 samples. Type: Expression profiling by array.

openGEO-OpenFeb 2018View details →
geo20/100

Late-onset sporadic Alzheimer’s disease modeling using patient-derived cells: A review

GEO Series GSE314553. Homo sapiens. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenJan 2026View details →
geo20/100

The Spontaneously Hypertensive Rat: An Experimental Model of Sulfur Dioxide-induced Airways Disease

GEO Series GSE4702. Rattus norvegicus. 16 samples. Type: Expression profiling by array.

openGEO-OpenOct 2006View details →
geo20/100

Modeling the pathogenesis of Charcot-Marie-Tooth disease type 1A using patient-specific iPSCs

GEO Series GSE97851. Homo sapiens. 7 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2018View details →
geo20/100

Gene expression in a Drosophila model of mitochondrial disease

GEO Series GSE10169. Drosophila melanogaster. 12 samples. Type: Expression profiling by array.

openGEO-OpenJan 2010View details →
geo20/100

Exploring transcriptome-wide changes in the brain-localized immune cells in a mouse model of Parkinson's Disease

GEO Series GSE148784. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2021View details →
geo20/100

Targeting Histone K4 Trimethylation for Treatment of Cognitive and Synaptic Deficits of Mouse Models of Alzheimer's Disease (ChIP-seq)

GEO Series GSE179999. Mus musculus. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenJul 2021View details →
geo20/100

Transcriptomic analyses of the effects of hepatic insulin signaling on hepatic gene expression in the PiZ mouse model of alpha-1-antitrypsin deficiency liver disease

GEO Series GSE179416. Mus musculus. 43 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJul 2022View details →
geo20/100

Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis [ATAC-Seq]

GEO Series GSE85630. Homo sapiens. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenDec 2016View details →
geo20/100

Mutant huntingtin stalls ribosomes and represses protein synthesis in a cellular model of Huntington disease (mRNA-Seq)

GEO Series GSE166695. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2021View details →
geo20/100

Gaucher Disease: Transcriptome Analyses Using Microarray or mRNA Sequencing in a Mouse Model Treated with velaglucerase alfa or imiglucerase

GEO Series GSE44675. Mus musculus. 110 samples. Type: Expression profiling by array; Expression profiling by high throughput sequencing.

openGEO-OpenSep 2013View details →
geo20/100

Moderate chronic treadmill exercise slows dopaminergic neuron loss in a rat model of Parkinson's disease and alters RNA content of circulating plasma exosomes

GEO Series GSE302532. Rattus norvegicus. 8 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2025View details →
geo20/100

Targeted protein expression analysis of skewed or drug-treated mouse T cells, and of serum from first disease vs flare in a model of Cutaneous Lupus Erythematosus

GEO Series GSE186095. Mus musculus. 16 samples. Type: Protein profiling by protein array.

openGEO-OpenJun 2022View details →
geo20/100

Gene Expression Profiling Using Huntington Disease Cell Culture Model and High-resolution Sp1 DNA-binding Site Mapping by ChIP-exo in STHdh Q7/Q7 cells

GEO Series GSE84058. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenJul 2016View details →
geo20/100

Inhaled Xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy [Xenon in IFNy blocker - mice]

GEO Series GSE272686. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2025View details →
geo20/100

Gene expression from embryoid bodies derived from HBG3 HB9 ES cells exposed to serum from a murine Huntington's disease model

GEO Series GSE95842. Mus musculus. 6 samples. Type: Expression profiling by array.

openGEO-OpenMar 2017View details →

ScienceDex guides

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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

Compare curated datasets

Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record