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975
datasets available to search
ShareScore release 0.9.0
Dataset results
975 results for “Spatial transcriptomics”
Spatial Transcriptomics reveals brain regional gene expression profiles in murine model of Periventricular Heterotopia
GEO Series GSE256342. Mus musculus. 76 samples. Type: Other.
Single nuclear RNA-seq and spatial transcriptomic analysis of anaplastic and favorable histology Wilms tumor
For more information, including a more complete description, data generator contact information, and reference, please see: https://scpca.alexslemonade.org/projects/SCPCP000006.
Mapping of cell types in the tumor microenvironment from tissue images via deep learning trained by spatial transcriptomics of lung adenocarcinoma
<p>Spatial transcriptomic data (10X Visium Platform) of lung adenocarcinoma that comprised thousands of spots with gene expression data and spatially registered H&E-stained tissue images from 22 samples.</p>
Synergistic Protective Effects of Ginsenoside Rb1 and Berberine Against Type 2 Diabetes Mellitus via the GDF15/HAMP Signaling Pathway Throughout the Liver Lobules: Insights from Spatial Transcriptomic
GEO Series GSE285791. Mus musculus. 171 samples. Type: Other.
Utilizing combined spatial transcriptomics to elucidate localized immune responses within human coronary arteries throughout the progression of atherosclerosis
GEO Series GSE277170. blank sample; Homo sapiens. 56 samples. Type: Other.
Differential microvascular endothelial cell responses in the retina in diabetes compared to the heart and kidneys, a spatial transcriptomic analysis.
GEO Series GSE263128. Mus musculus. 24 samples. Type: Other.
Single-cell and spatial transcriptomic atlas of pathological scars uncovers neuro-fibroblast crosstalk mechanisms across scar types
GEO Series GSE307504. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing; Other.
Spatial Transcriptomic Analysis of Early and Late Stages of Hidradenitis Suppurativa
GEO Series GSE294009. Homo sapiens. 204 samples. Type: Other.
Redefining electrical stimulation safety using spatial transcriptomics
GEO Series GSE202425. Rattus norvegicus. 6 samples. Type: Expression profiling by high throughput sequencing; Other.
Lysosomal sequestration of PARP inhibitors drives heterogeneous accumulation in ovarian cancer to increase efficacy [Spatial Transcriptomics]
GEO Series GSE281519. Homo sapiens. 132 samples. Type: Other.
Spatial transcriptomics of fixed tissue micro-regions using Pick-Seq
GEO Series GSE158564. Homo sapiens. 99 samples. Type: Expression profiling by high throughput sequencing.
Spatial Transcriptomics Quantification
The Spatial Transcriptomics Quantification pipeline (STQ) enables deconvolution of mouse and human reads, alignment of imaging and spatial gene expression, and extraction of quantitative morphology and imaging features for 10x Genomics Visium spatial transcriptomics data together with matching H&E whole-slide images, facilitating integrated analysis of spatial gene expression and histology. Its utility in integrating transcriptomic and image-derived features support multimodal characterization of tumor microenvironments.
Spatial Transcriptomics of RA Synovium
<p>Seurat object for Cosmx data of RA tissue.</p>
Spatial Transcriptomics Sequencing of only 2 Slides (Extraslides from Project 651)
<p>Dataset from BMFZ Spatial Transcriptomics Sequencing from aortic tissues (d7+d14, DMSO, PPE, PPE+ TrafSTOP) (Extraslides from Project 651)</p>
Spatial Transcriptomics Reveals Spatially Diverse Cancer-Associated Fibroblast in Lung Squamous Cell Carcinoma Linked to Tumor Progression
<p><span><span>While cancer-associated fibroblasts (CAFs) are crucial in influencing tumor growth and immune responses in lung cancer, we still lack a comprehensive understanding of their spatial organization associated with tumor progression and clinical outcomes. This gap highlights the need to elucidate how the intricate spatial arrangement of CAFs affects their interactions within the tumor microenvironment, ultimately shaping cancer progression and patient prognosis. Here, we unveil the spatial diversity of CAFs in lung squamous cell carcinoma (LUSC), a prevalent and aggressive lung cancer type, elucidating their impact on tumor progression and patient outcomes using spatial transcriptomics (ST). Image-based ST data from 33 LUSC patients demonstrated a significant association of spatial interactions of tumor epithelium and CAFs with tumor size and metabolic activity measured by [<sup>18</sup>F]fluorodeoxyglucose PET. Furthermore, the proximity of fibroblasts to tumor epithelial cells was linked to recurrence-free survival in LUSC patients. By characterizing CAFs based on their spatial relationship, we identified distinct molecular signatures related to spatially distinct fibroblast subpopulations. In addition, barcode-based ST data from 8 LUSC patients revealed spatially overlapping fibroblast regions characterized by upregulated glycolysis pathways. </span></span><span><span><span><span>Our study underscores the importance of the complex spatial dynamics of the tumor microenvironment revealed by ST and its implications for patient outcomes in LUSC.</span></span></span></span></p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.