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1,102
datasets available to search
ShareScore release 0.9.0
Dataset results
1,102 results for “human use”
Pathogenic pathways in early onset autosomal recessive Parkinson’s disease discovered using isogenic human dopaminergic neurons
GEO Series GSE140076. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Rapid and efficient generation of myelinating oligodendrocytes from human induced pluripotent stem cells using a combination of three transcription factors [hiPSC]
GEO Series GSE79912. Homo sapiens. 20 samples. Type: Expression profiling by array.
Stabilization of OCT4 synthetic mRNA in adult human skin cells using small molecules
GEO Series GSE40444. Homo sapiens. 8 samples. Type: Expression profiling by array.
Study of human immune and memory T cells using microarray
GEO Series GSE11103. Homo sapiens. 41 samples. Type: Expression profiling by array.
Modeling sex differences in humans using isogenic induced pluripotent stem cells
GEO Series GSE145079. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Precise mapping of the transcription start sites of human microRNAs using DROSHA knockout cells
GEO Series GSE80258. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
Proof of Gene Doping in a Mouse Model with a Human Erythropoietin Gene Transferred Using an Adenoviral Vector
GEO Series GSE178336. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Clinical, Molecular and Genetic Validation of a Murine Orthotopic Xenograft Model of Pancreatic Adenocarcinoma using Fresh Human Specimens
GEO Series GSE46385. Homo sapiens. 47 samples. Type: Expression profiling by array.
Background analysis using yeast RNA on the mouse and human array
GEO Series GSE23396. Homo sapiens; Saccharomyces cerevisiae; Mus musculus. 10 samples. Type: Expression profiling by array.
Rational design of a SOCS1-edited tumor infiltrating lymphocyte therapy for solid tumors using CRISPR/Cas9 screens [TIL5746_human_invitro]
GEO Series GSE237694. Homo sapiens. 2 samples. Type: Other.
Generation of multi-omic datasets using high-throughput molecular profiling of DNA methylation human data
GEO Series GSE281305. Homo sapiens. 40 samples. Type: Methylation profiling by genome tiling array.
Effect of RIG-I activation and thymidine phosphorylase inhibition using Tipiracil on gene expression of human endothelial cells.
GEO Series GSE204809. Homo sapiens. 14 samples. Type: Expression profiling by high throughput sequencing.
Gene expression profile at single-cell level of human Simpson-Golabi-Behdel syndrome (SGBS) cells undergoing adipogenesis following knock-down of target genes using CRISPRi
GEO Series GSE217812. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.
24hr CA treatment vs. DMSO in HCT116 cells (from 'Identification of CDK8 and CDK19 substrates in human cells using cortistatin A and quantitative phosphoproteomics')
GEO Series GSE78506. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Insight on amoebiasis using a 3D model of the human intestine
GEO Series GSE128194. Entamoeba histolytica HM-1:IMSS; Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Epigenomic landscape of human cumulus cells in premature ovarian insufficiency using single-base resolution methylome and hydroxymethylome. [scWGBS_seq]
GEO Series GSE267643. Homo sapiens. 6 samples. Type: Methylation profiling by high throughput sequencing.
Identification of human tRNA molecules bound to human cytomegalovirus capsid using cryoEM and Next-generation sequencing
GEO Series GSE167037. Homo sapiens. 1 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Toward a functional annotation of the human genome using artificial transcription factors
GEO Series GSE677. Homo sapiens. 132 samples. Type: Expression profiling by array.
RNAseq profiling of eSCC human cell line (KYSE-410) knocked-out for SHIP2 using CRISPR/Cas9 technology
GEO Series GSE311621. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.
Modeling cellular responses to serum and vitamin D in microgravity using a human kidney microphysiological system
The microgravity environment aboard the International Space Station (ISS) provides a unique stressor that can help understand underlying cellular and molecular drivers of pathological changes observed in astronauts with the ultimate goals of developing strategies to enable long- term spaceflight and better treatment of diseases on Earth. We used this unique environment to evaluate the effects of microgravity on kidney proximal tubule epithelial cell (PTEC) response to serum exposure and vitaminD biotransformation capacity. To test if microgravity alters the pathologic response of the proximal tubule to serum exposure, we treated PTECs cultured in a microphysiological system (PT-MPS) with human serum and measured biomarkers of toxicity and inflammation (KIM-1 and IL-6) and conducted global transcriptomics via RNAseq on cells undergoing flight (microgravity) and respective controls(ground). Given the profound bone loss observed in microgravity and PTECs produce the active form of vitamin D, we treated 3D cultured PTECs with 25(OH)D 3 (vitamin D) and monitored vitamin D metabolite formation, conducted global transcriptomics via RNAseq, and evaluated transcript expression of CYP27B1, CYP24A1, or CYP3A5 in PTECs undergoing flight (microgravity) and respective ground controls. We demonstrated that microgravity neither altered PTEC metabolism of vitamin D nor did it induce a unique response of PTECs to human serum, suggesting that these fundamental biochemical pathways in the kidney proximal tubule are not significantly altered by short-term exposure to microgravity. Given the prospect of extended spaceflight, more study is needed to determine if these responses are consistent with extended (greater than 6 months) exposure to microgravity.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.