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121 results for “Allosterism”

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geo24/100

ssDNA is an allosteric regulator of the C. crescentus SOS-independent DNA damage response transcription activator, DriD

GEO Series GSE197978. Caulobacter vibrioides. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenMay 2022View details →
geo24/100

H3 K27M and EZHIP impede H3K27-methylation spreading by inhibiting allosterically stimulated PRC2.

GEO Series GSE151983. Mus musculus; Drosophila melanogaster. 43 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenOct 2020View details →
geo24/100

Direct Selection of an Allosteric RNA-Cleaving DNAzyme for a Protein Target: A Specific DNAzyme for Eosinophil Peroxidase to Monitor Airway Eosinopilia

GEO Series GSE217946. synthetic construct. 1 samples. Type: Other.

openGEO-OpenNov 2023View details →
geo24/100

REPROGRAMMING CBX8-PRC1 FUNCTION WITH A POSITIVE ALLOSTERIC MODULATOR

GEO Series GSE182592. Homo sapiens. 39 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenJan 2022View details →
geo24/100

The allosteric landscape of the Src kinase

GEO Series GSE247740. Saccharomyces cerevisiae; Homo sapiens. 118 samples. Type: Other.

openGEO-OpenApr 2024View details →
geo24/100

Small molecule probe for IBD risk variant GPR65 I231L alters cytokine signaling networks through positive allosteric modulation

GEO Series GSE243692. Mus musculus. 90 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJun 2024View details →
geo24/100

Characterization of TNG348: a selective, allosteric USP1 inhibitor that synergizes with PARP inhibitors in tumors with DNA damage repair alterations

GEO Series GSE284239. Homo sapiens. 11 samples. Type: Other.

openGEO-OpenDec 2024View details →
geo24/100

Suppression of NRF2-dependent cancer growth by a covalent allosteric molecular glue

GEO Series GSE278482. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2025View details →
geo24/100

Gene expression profiling of A549 human lung cancer cell line treated with allosteric inhibitors targeting atypical PKCs

GEO Series GSE63593. Homo sapiens. 16 samples. Type: Expression profiling by array.

openGEO-OpenJan 2017View details →
geo24/100

Negative allosteric modulation of mGluR5 partially corrects pathophysiology in a mouse model of Rett Syndrome

GEO Series GSE82068. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2016View details →
geo24/100

NMDA receptor positive allosteric modulator induced genome wide gene expression changes in neuronal cultures

GEO Series GSE139080. Rattus norvegicus. 8 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2021View details →
geo24/100

Transcriptomic changes induced by allosteric inhibitor RMC-4550 in FLT3 and KIT mutant human AML cell lines

GEO Series GSE217359. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2022View details →
geo24/100

Genetic and functional modulation by agonist MRS5698 and allosteric enhancer LUF6000 at the native A3 adenosine receptor in HL-60 cells.

GEO Series GSE302191. Homo sapiens. 12 samples. Type: Expression profiling by array.

openGEO-OpenJul 2025View details →
zenodo24/100

Code and data for "An allosteric switch ensures efficient unidirectional information transmission by the histidine kinase DesK from Bacillus subtilis"

<p>Code and data used in the paper &quot;An allosteric switch ensures efficient unidirectional information transmission in the histidine kinase DesK from&nbsp;<em>Bacillus subtilis&quot;</em></p>

opencc-by-4.0Jan 2022View details →
ClinicalTrials.gov24/100

Phase I Dose Escalation Study With an Allosteric AKT 1/2 Inhibitor in Patients

ClinicalTrials.gov study NCT01915576. IPD Sharing: Not stated. Countries: 4. Publications: 0.

restrictedIPD-UNDECIDEDFeb 2026View details →
geo24/100

Paraspeckle Protein NONO Regulates Active Chromatin by Allosterically Stimulating NSD1

GEO Series GSE304363. Mus musculus; Homo sapiens. 36 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenAug 2025View details →
geo24/100

Mrg15 allosterically activates Ash1’s H3K36 methyltransferase activity and facilitates Ash1’s trithorax group protein function in Drosophila

GEO Series GSE93100. Drosophila melanogaster. 21 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.

openGEO-OpenOct 2017View details →
geo24/100

RNA-seq of prostate cancer cell lines with acquired resistance to AKT inhibitors GDC-0068 (ATP competitive) or MK206 (allosteric)

GEO Series GSE139178. Homo sapiens. 28 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2020View details →
geo24/100

Global mapping of the energetic and allosteric landscapes of protein binding domains

GEO Series GSE184042. Saccharomyces cerevisiae. 24 samples. Type: Other.

openGEO-OpenSep 2021View details →
geo20/100

EED226, an allosteric PRC2 inhibitor, modulates gene transcription in EZH2 mutant lymphoma cell Karpas422 through PRC2 inhibition

GEO Series GSE81267. Homo sapiens. 33 samples. Type: Expression profiling by array.

openGEO-OpenJan 2017View details →

ScienceDex guides

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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

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Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record