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10,068 results for “Heart”
Energy management strategies for ectothermic vertebrates: temperature and heart rate as independent proxies
<p>Filtered data used for analysis of energy management strategies in three different species. R script provides an example of the across- and within-individual analysis. </p>
Multi-modal phantom experiments, mimicking flow through the mitral heart valve
<p>In this repository all experimental data obtained from a phantom study on the left heart, including a deformable mitral valve, is reported. Using invasive catheter pressure measurements, magnetic resonance imaging and ultrasound imaging, several parameters relevant to diagnosing heart valve disease were measured on the phantom. The data is reported in MS excel files (xlsx format) and the geometry of the phantom is reported in STL and STEP file format, together with an exploded view, indicating how the parts are put together.</p>
HEartS Professional Survey: Charting the effects of COVID-19 on working patterns, income, and wellbeing among performing arts professionals in the United Kingdom (April-May 2021)
<p>These data were collected using the <em>HEartS Professional Survey II</em> from performing arts workers in the United Kingdom in April–May 2021. <em>HEartS Professional II </em>is an adaptation of the <em>HEartS Professional I</em> survey which was used in April–June 2020 (<a href="https://doi.org/10.5061/dryad.s7h44j14z">https://doi.org/10.5061/dryad.s7h44j14z</a>). Both surveys were designed as multi-strategy data collection tools with two main purposes: (1) to chart working patterns, income, sources of support, and indicators of mental and social well-being in order to identify trends in the effects of the lockdown at the time and (2) to explore the individual work and wellbeing experiences of performing arts professionals in their own words, in order to identify the subjective effects of lockdown in terms of challenges and opportunities. The survey covers six areas: (1) demographics; (2) information on illness or self-isolation related to COVID-19; (3) work profiles and income; (4) changes to work profiles and income as a result of the pandemic, as well as sources of support; (5) open-response questions about work and wellbeing experiences of lockdown including challenges and opportunities; and (6) validated measures of health, wellbeing, and social connectedness.<span> The <em>HEartS Professional</em> surveys are adaptations of the Depression, loneliness, online survey, pandemic, performing arts professionals, Social Isolation, UK adult sample, well-being, Work </span>which charts the Health, Economic, and Social impacts of the ARTs (<a href="https://doi.org/10.5061/dryad.3r2280gdj">https://doi.org/10.5061/dryad.3r2280gdj</a>). </p>
Real-time influence of intracellular acidification and Na+/H+ exchanger inhibition on in-cell pyruvate metabolism in the perfused mouse heart: A 31P-NMR and hyperpolarized 13C-NMR study
<p>This dataset contains primary data for DOI: 10.1002/nbm.4993</p> <p>NMR in Biomedicine. 2023; 10;e4993</p> <p>Title: Real-time influence of intracellular acidification and Na+/H+ exchanger inhibition on in-cell pyruvate metabolism in the perfused mouse heart: A 31P-NMR and hyperpolarized 13C-NMR study</p> <p>Authors: David Shaul, Naama Lev-Cohain, Gal Sapir, Jacob Sosna, J. Moshe Gomori, Leo Joskowicz, Rachel Katz-Brull</p> <p> </p> <p>Description:</p> <p>These primary datasets contains data presented in the above publication and consist of 31P- (at thermal equilibrium) and hyperpolarized 13C-NMR spectra. </p> <p>Please consult the Archive Guide.</p>
Heart graffiti in Villarrubia Jail (Spain)
The 18th century jail of Villarrubia de los Ojos, built on the ground floor of the old City Hall building, is located in the center of the town of Villarrubia de los Ojos (Ciudad Real, Spain). As in other jails of the same period, the walls of some cells contain engravings (graffiti). Among all of them here it is possible to distinguish a heart. 3D model made using 56 images in Reality Capture. Additional processing completed in Geomagic Wrap, Zbrush, Substance Designer, and Blender. Bibliography: López-Menchero, V.M. et al. (2020): "Los graffiti carcelarios de la Edad Media y Moderna en la provincia de Ciudad Real: Un estudio comparado", in De los controles disciplinarios a los controles securitarios: Actas del II Congreso Internacional sobre la Historia de la Prisión y las Instituciones Punitivas, pp. 37-54. Source: Objaverse 1.0 / Sketchfab
Increased Drp1 acetylation by lipid overload induces cardiomyocyte death and heart dysfunction
<p>Metabolic syndrome is a cluster of abnormalities characterized by obesity and insulin resistance, which compromise energy metabolism, damage mitochondria, cause cardiomyocyte death, and eventually impair heart contraction and relaxation performance. Despite the increasing prevalence of heart complications in obese and diabetic patients, our knowledge on how obese and diabetes mellitus impair heart function is very limited. In this study, we used animal and cell culture models in rodents or monkeys and generated lipid overload models to mimic obesity conditions. We found that excessive lipid supply decreased nicotinamide adenine dinucleotide (oxidized) levels and increased the acetylation of a fission protein Drp1 at a specific lysine residue (K642). Drp1 acetylation at K642 activated Drp1 through phosphorylation, mitochondrial translocation, and oligomerization. The excessively activated Drp1 had higher GTPase activity, bound with VDAC1 on mitochondria, induced mitochondrial fission, and caused cardiomyocyte death. These findings provide new information regarding how lipid overload regulates redox environment, protein acetylation, and the function of mitochondrial fission protein Drp1 in the heart.</p>
Dataset of "Optical Signatures of Thermal Damage on ex-vivo Brain, Lung and Heart Tissues using Time-Domain Diffuse Optical Spectroscopy"
<p>Dataset for the article entitled "Optical Signatures of Thermal Damage on ex-vivo Brain, Lung and Heart Tissues using Time-Domain Diffuse Optical Spectroscopy" </p> <p> </p> <p>Abstract:</p> <p> </p> <p>Thermal Therapies treat tumors by means of heat, greatly reducing pain, post-operation complications, and cost as compared to traditional methods. Yet, effective tools to avoid under- or over-treatment are mostly needed, to guide surgeons in laparoscopic interventions.<br>In this work, we investigated the temperature-dependent optical signatures of ex-vivo calf brain, lung, and heart tissues, based on the reduced scattering and absorption coefficients in the near-infrared spectral range (657 to 1107 nm). These spectra were measured by time domain diffuse optics, applying a step-like spatially homogeneous thermal treatment at 43 °C, 60 °C, and 80 °C.<br>We found three main increases in scattering spectra, possibly due to the denaturation of collagen, myosin, and proteins secondary structure.<br>After 75 °C, we found the rise of two new peaks at 770 and 830 nm in the absorption spectra due to the formation of a new chromophore, possibly related to hemoglobin or myoglobin.<br>This research marks a significant step forward in controlling thermal therapies with diffuse optical techniques by identifying several key markers of thermal damage. This could enhance the ability to monitor and adjust treatment in real-time, promising improved outcomes in tumor therapy.</p> <p> </p> <p> </p> <p>Authors:</p> <p>ALESSANDRO BOSSI , LEONARDO BIANCHI , PAOLA SACCOMANDI , AND ANTONIO PIFFERI<br>Politecnico di Milano</p> <p> </p> <p> </p> <p><a href="https://opg.optica.org/boe/fulltext.cfm?uri=boe-15-4-2481&id=548108" target="_blank" rel="noopener">Link to the article</a></p>
Transcriptomic atlas reveals organ-specific disease tolerance in sickle cell mice. Dataset for HbAA heart injected or not with heme
<p>The objective of this experiment was to explore the transcriptome of the HbSS Townes mouse model of sickle cell disease.Townes model mice carry several human hemoglobin knock-in genes replacing the endogenous mouse genes and may be useful in studying sickle cell disease.All mice were genotyped, age- and sex-matched littermates. All HbAA (control, normal human hemoglobin) vs HbSS (sickle cell disease, mutated human hemoglobin) mice were used for experimentations at 6-8 weeks of age, to limit intra-group heterogeneity. Hemin (Ferriprotoporphyrin IX) was purchased from Frontiers Scientific and injected intravenously (iv.) in a retroorbital sinus at a concentration of 24 µmol/kg. Control mice received PBS instead. Mice were anesthetized with isoflurane 2-3% for injections, blood collection and sacrifice. All mice were sacrificed by cervical dislocation, 4 hours after injection.</p> <p>The results of heart (indicated coeur) from HbAA mice injected or not with heme are presented here . </p> <p>The results of heart (indicated coeur) from HbSS mice injected or not with heme can be found at number 10.5281/zenodo.10964159</p> <p>Thirty μm-thick frozen tissue sections of kidneys were cut as above and homogenized in 200μL of 1-Thioglycerol/Homogenization Solution (Maxwell® 16 LEV simplyRNA Tissue Kit Promega AS1280). The quality and quantity of mRNA were evaluated using a 2100 bioanalyzer with TNA 6000 NanoKits (all Agilent Technologies, Palo Alto, CA, USA). RNA Integrity Numbers superior to 7 were eligible for subsequent reverse transcription into cDNA. RNAseq was performed at the GenomIC plateform Cochin Institute INSERM U1016. After RNA extraction, RNA quality (RNA integrity number) was estimated. 1μg of high-quality total RNA sample (RIN &gt;7) was processed to build up the libraries, using TruSeq Stranded mRNA kit (Illumina) according to manufacturer instructions. Briefly, purified poly-A containing mRNA molecules were fragmented and reverse-transcribed using random primers. Replacement of dTTP by dUTP during second strand synthesis allowed us to achieve strand specificity. Addition of a single A base to the cDNA was followed by ligation of Illumina adapters.<br>Libraries were quantified by qPCR using KAPA Library Quantification Kits for Illumina Libraries (KapaBiosystems, Wilmington, MA). Library profiles were assessed using DNA High Sensitivity LabChip kits on an Agilent Bioanalyzer. Libraries were sequenced on an Illumina Nextseq 500 instrument using 75 base-lengths read V2 chemistry in a paired-end mode. After sequencing, primary analysis based on AOZAN software (ENS, Paris), was applied to demultiplex and control the quality of the raw data (based of FastQC modules / version 0.11.5).</p> <p>The dataset here represents 4 groups of mice, 4 mice per group as follows: HbAA PBS, HbAA heme, HbSS PBS, HbSS heme. </p>
Transcriptomic atlas reveals organ-specific disease tolerance in sickle cell mice. Dataset for HbSS heart injected or not with heme
<div> <p>The objective of this experiment was to explore the <span>transcriptome</span> of the <span>HbSS Townes</span> <span>mouse model</span> of <span>sickle cell disease</span>.Townes model mice carry several human hemoglobin <span>knock-in</span> genes replacing the endogenous mouse genes and may be useful in studying <span>sickle cell disease</span>.All mice were <span>genotyped</span>, age- and sex-matched littermates. All <span>HbAA</span> (control, normal human hemoglobin) vs HbSS (<span>sickle cell disease</span>, mutated human hemoglobin) mice were used for experimentations at 6-8 weeks of age, to limit intra-group <span>heterogeneity</span>. <span>Hemin</span> (<span>Ferriprotoporphyrin IX</span>) was purchased from <span>Frontiers Scientific</span> and injected <span>intravenously</span> (iv.) in a retroorbital sinus at a concentration of 24 µmol/kg. Control mice received <span>PBS</span> instead. Mice were anesthetized with <span>isoflurane</span> 2-3% for injections, blood collection and sacrifice. All mice were sacrificed by cervical dislocation, 4 hours after injection.</p> <p>The results of heart (indicated coeur) from HbSS mice injected or not with <span>heme</span> are presented here . </p> <p>The results of heart (indicated coeur) from <span>HbAA</span> mice injected or not with <span>heme</span> can be found at number 10.5281/zenodo.10964042</p> <p>Thirty μm-thick frozen tissue sections of kidneys were cut as above and homogenized in 200μL of 1-Thioglycerol/Homogenization Solution (Maxwell® 16 LEV simplyRNA Tissue Kit <span>Promega</span> AS1280). The quality and quantity of mRNA were evaluated using a 2100 bioanalyzer with TNA 6000 NanoKits (all <span>Agilent Technologies</span>, <span>Palo Alto, CA</span>, <span>USA</span>). RNA Integrity Numbers superior to 7 were eligible for subsequent <span>reverse transcription</span> into <span>cDNA</span>. <span>RNAseq</span> was performed at the GenomIC plateform <span>Cochin</span> Institute INSERM U1016. After <span>RNA extraction</span>, RNA quality (<span>RNA integrity number</span>) was estimated. 1μg of high-quality total RNA sample (RIN &gt;7) was processed to build up the libraries, using TruSeq Stranded mRNA kit (<span>Illumina</span>) according to manufacturer instructions. Briefly, purified <span>poly-A</span> containing mRNA molecules were fragmented and <span>reverse-transcribed</span> using random <span>primers</span>. Replacement of dTTP by dUTP during second strand synthesis allowed us to achieve strand specificity. Addition of a single A base to the <span>cDNA</span> was followed by <span>ligation</span> of <span>Illumina</span> adapters.<br>Libraries were quantified by <span>qPCR</span> using <span>KAPA Library Quantification</span> Kits for <span>Illumina</span> Libraries (KapaBiosystems, <span>Wilmington</span>, MA). Library profiles were assessed using DNA High Sensitivity LabChip kits on an <span>Agilent</span> Bioanalyzer. Libraries were sequenced on an <span>Illumina</span> Nextseq 500 instrument using 75 base-lengths read V2 chemistry in a <span>paired-end</span> mode. After sequencing, primary analysis based on AOZAN software (ENS, <span>Paris</span>), was applied to <span>demultiplex</span> and control the quality of the <span>raw data</span> (based of FastQC modules / version 0.11.5).</p> <p>The dataset here represents 4 groups of mice, 4 mice per group as follows: HbAA <span>PBS</span>, HbAA <span>heme</span>, HbSS <span>PBS</span>, <span>HbSS</span> <span>heme</span>. </p> </div>
High heart rates in hunting porpoises
<p class="MsoPlainText">The impressive breath-hold capabilities of marine mammals are facilitated by both enhanced O<sub>2</sub> stores and reductions in the rate of O<sub>2</sub> consumption via peripheral vasoconstriction and bradycardia, coined the dive response. <span>Many studies have focused on the extreme role of the dive response in maximizing dive duration in marine mammals, but few have addressed how these adjustments may compromise the capability to hunt, digest and thermoregulate during routine dives</span>. Here we use DTAGs which record heart rate together with foraging and movement behaviour to investigate how O<sub>2</sub> management is balanced between the need to dive and forage in five wild harbour porpoises that hunt thousands of small prey daily during continuous shallow diving. Dive heart rate was moderate (median minimum 47-69 bpm) and relatively stable across dive types, dive duration (0.5-3.3 min), and activity. A moderate dive response, allowing for some perfusion of peripheral tissues, may be essential for fuelling the high field metabolic rates required to maintain body temperature and support digestion during diving in these small, continuously-feeding cetaceans. Thus, despite having the capacity to prolong dives via a strong dive response, for these shallow-diving cetaceans, it appears to be more efficient to maintain circulation while diving: extreme heart-rate gymnastics are for deep dives and emergencies, not everyday use.</p>
Heart Disease XML Strain
<p>Disclaimer: These datasets were generated during the course of academic research conducted at the Faculty of Medicine, The Chinese University of Hong Kong, which received ethics approval by The Joint Chinese University of Hong Kong – New Territories East Cluster Clinical Research Ethics Committee of the Hospital Authority. They have been anonymised and are deposited for further advancement of medical research in full compliance with University Regulations and Policy on Dataset Deposit and Sharing. For additional information: https://libguides.lib.cuhk.edu.hk/RDM/dataset_deposit</p> <p> </p> <p>Access is permitted for research purposes only.</p> <p> </p> <p>The use of these datasets should provide acknowledgements of such efforts by citing this DOI.</p>
Singing strategies are linked to perch use on foraging territories in heart-nosed bats
<p>These data include the GPS data of 14 VHF telemetry tracked heart-nosed bats (<em>Cardioderma cor</em>) and associated singing behavior collected during the long dry season (May to October) in Tanzania. These data were used to establish that singing occurs on nighttime foraging areas, and that foraging areas are exclusive and repeatedly used, supporting the hypothesis that <em>C. cor</em> maintain individualistic foraging territories with singing. Times and locations of singing are included in the data set and linked to the GPS waypoints of perches individuals used repeatedly during then 4-6 nights of tracking. GPS data is organized by list of separate waypoints and whether they were used for singing. Furthermore, individuals sit in trees and sing for long stretches of time, and thus these durations were subsampled into 2 minute intervals and associated with the perch location to create a dateset of points for Kernal Density Estimates. Times and perch locations for KDE, including associated singing behavior, are also included. Finally, singing duration of each individual is broken down by perch, night, and hour. Of the 14 tracked individuals, 13 are male (one of which stopped singing soon after tracking commenced) and one is a nonsinging female. </p>
Early Detection Of Cardiovascular Risk Factors And Definition Of Psychosocial Profile In Women Through A Systematic Approach: The Monzino Women Heart Center's Experience
<p>The raw dataset is related to the analysis of CV risk factors and psychosocial profile in women enrolled in a CV prevention program </p>
Heart rate variability: Can it serve as a marker of mental health resilience?
<p>Heart rate variability: Can it serve as a marker of mental health resilience?</p> <p>Background: Stress resilience influences mental well-being and vulnerability to psychiatric disorders. Usually, measurement of resilience is based on subjective<br> reports, susceptible to biases. It justifies the need for objective biological/physiological biomarkers of resilience. One promising candidate as biomarker of mental<br> health resilience (MHR) is heart rate variability (HRV). The evidence for its use was reviewed in this study.<br> Methods: We focused on the relationship between HRV (as measured through decomposition of RR intervals from electrocardiogram) and responses to laboratory<br> stressors in individuals without medical and psychiatric diseases. We conducted a bibliographic search of publications in the PubMed for January 2010–September<br> 2018.<br> Results: Eight studies were included. High vagally mediated HRV before and/or during stressful laboratory tasks was associated with enhanced cognitive resilience to<br> competitive/self-control challenges, appropriate emotional regulation during emotional tasks, and better modulation of cortisol, cardiovascular and inflammatory<br> responses during psychosocial/mental tasks.<br> Limitations: All studies were cross-sectional, restricting conclusions that can be made. Most studies included only young participants, with some samples of only<br> males or females, and a limited array of HRV indexes. Ecological validity of stressful laboratory tasks remains unclear.<br> Conclusions: Vagally mediated HRV may serve as a global index of an individual's flexibility and adaptability to stressors. This supports the idea of HRV as a plausible,<br> noninvasive, and easily applicable biomarker of MHR. In future longitudinal studies, the implementation of wearable health devices, able to record HRV in naturalistic<br> contexts of real-life, may be a valuable strategy to gain more reliable insight into this topic.</p>
Raw Data for the article: miRNA expression analysis in the human heart: Undifferentiated progenitors vs. bioptic tissues-Implications for proliferation and ageing
<p>In developed countries, cardiovascular diseases are currently the first cause of death. Cardiospheres (CSs) and cardiosphere-derived cells (CDCs) have been found to have the ability to regenerate the myocardium after myocardial infarction (MI). In recent years, much effort has been made to gain insight into the human heart repair mechanisms, in which miRNAs have been shown to play an important role. In this regard, to elucidate the involvement of miRNAs, we evaluated the miRNA expression profile across human heart biopsy, CSs and CDCs using microarray and next-generation sequencing (NGS) technologies. We identified several miRNAs more represented in the progenitors, where some of them can be responsible for the proliferation or the maintenance of an undifferentiated state, while others have been found to be downregulated in the undifferentiated progenitors compared with the biopsies. Moreover, we also found a correlation between downregulated miRNAs in CSs/CDCs and patient age (eg miR-490) and an inverse correlation among miRNAs upregulated in CSs/CDCs (eg miR-31).</p>
Raw Data for the article: Patient-Specific Analysis of Ascending Thoracic Aortic Aneurysm with the Living Heart Human Model
<p>In ascending thoracic aortic aneurysms (ATAAs), aneurysm kinematics are driven by ventricular traction occurring every heartbeat, increasing the stress level of dilated aortic wall. Aortic elongation due to heart motion and aortic length are emerging as potential indicators of adverse events in ATAAs; however, simulation of ATAA that takes into account the cardiac mechanics is technically challenging. The objective of this study was to adapt the realistic Living Heart Human Model (LHHM) to the anatomy and physiology of a patient with ATAA to assess the role of cardiac motion on aortic wall stress distribution. Patient-specific segmentation and material parameter estimation were done using preoperative computed tomography angiography (CTA) and ex vivo biaxial testing of the harvested tissue collected during surgery. The lumped-parameter model of systemic circulation implemented in the LHHM was refined using clinical and echocardiographic data. The results showed that the longitudinal stress was highest in the major curvature of the aneurysm, with specific aortic quadrants having stress levels change from tensile to compressive in a transmural direction. This study revealed the key role of heart motion that stretches the aortic root and increases ATAA wall tension. The ATAA LHHM is a realistic cardiovascular platform where patient-specific information can be easily integrated to assess the aneurysm biomechanics and potentially support the clinical management of patients with ATAAs.</p>
7T Whole Body DMI Proposal Preliminary Data (Brain, Liver, Muscle, Heart)
<p>Deuterium 2H-MRSI preliminary spectra acquired in vivo (brain, liver, heart, muscle) using 3D chemical shift imaging. Matrix size: 16x16x14, 12 mm isotropic, TR=350 ms, TA= 14 min. </p>
Raw Data or the article: Physiopathology and Diagnosis of Congestive Heart Failure: Consolidated Certainties and New Perspectives
<p>Volume overload and fluid congestion are a fundamental issue in the assessment and management of patients with heart failure (HF). Recent studies have found that in acute decompensated heart failure (ADHF), right and left-sided pressures generally start to increase before any notable weight changes take place preceding an admission. ADHF may be a problem of volume redistribution among different vascular compartments instead of, or in addition to, fluid shift from the interstitial compartment. Thus, identifying heterogeneity of volume overload would allow guidance of tailored therapy. A comprehensive evaluation of congestive HF needs to take into account myriad parameters, including physical examination, echocardiographic values, and biomarker serum changes. Furthermore, potentially useful diagnostic tools include bioimpedance to measure intercompartmental fluid shifts, and evaluation of ultrasound lung comets to detect extravascular lung water.</p>
Factors associated with coronary heart disease in COPD patients and controls
<p><strong><span>Background</span></strong></p> <p><span>COPD and coronary heart disease (CHD) frequently co-occur, yet which COPD phenotypes are most prone to CHD is poorly understood. </span><span>The aim of this study was to see whether COPD patients did have a true higher risk for CHD than subjects without COPD, and to examine a range of potential factors associated with CHD in COPD patients and controls</span></p> <p><strong><span>Methods</span></strong></p> <p><span>347 COPD patients and 428 non-COPD controls, were invited for coronary computed tomography angiography (CCTA) and pulmonary CT. Arterial blood gas, bioelectrical impedance and lung function was measured, and a detailed medical history taken. The CCTA was evaluated for significant coronary stenosis and calcium score (CaSc), and emphysema defined as >10% of total area <-950 Hounsfield units. </span></p> <p><strong><span>Results</span></strong></p> <p><span>12.6% of the COPD patients and 5.7% of the controls had coronary stenosis (p<0.01), whereas 55.9% of the COPD patients had a CaSc>100 compared to 31.6% of the controls (p<0.01). In a multivariable model adjusting for sex, age, body composition, pack-years, CRP, cholesterol/blood pressure lowering medication use and diabetes mellitus, the OR (95% CI) for having significant stenosis was 1.80 (0.86-3.78) in COPD patients compared with controls. In a similar model, the OR (95% CI) for having CaSc>100 was 1.68 (1.12-2.53) in COPD patients compared with controls. Examining the risk of significant stenosis and CaSc>100 among COPD patients, no variable was associated with significant stenosis, whereas male sex [OR 2.85 (1.56-5.21)], age [OR 3.74 (2.42-5.77)], statin use [OR 2.23 (1.23-4.50)] were associated with CaSc>100, after adjusting for body composition, pack-years, C-reactive protein, use of angiotensin converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs), diabetes, emphysema score, GOLD category, exacerbation frequency, eosinophilia, and hypoxemia.</span></p> <p><strong><span>Conclusion</span></strong></p> <p><span>COPD patients were more likely to have CHD, but neither emphysema score, lung function, exacerbation frequency, nor hypoxemia predicted presence of either coronary stenosis or CaSc>100. </span></p>
Data Archive for "Acceleration as a proxy for energy expenditure in a facultative-soaring bird: comparing dynamic body acceleration and time-energy budgets to heart rate"
<p>Heart rate, acceleration, and respirometry data from four wild-caught gulls during climate chamber and treadmill calibration measurements (2018), as well as heart rate and acceleration data from five free-ranging gulls from a colony on Texel, NL during the breeding season (May - July, 2019). </p> <p> </p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.