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opencc-by-4.0Dec 2021View details →

Figure 3. – A in The lungs of extinct and extant coelacanths: a morphological and histological review

Figure 3. – A: Latimeria chalumnae. Specimen CCC5 (MNHN- ZA-AC-2012-3); Azocarmin preparation, from Millot et al. (1978). Cross section showing the vestigial lung, surrounded by four plates (arrowheads 1 to 4). Two lumen ramifications (lc) of the lung are seen (see Cupello et al., 2017a). The lumen of the lung is bordered by a monostratified epithelium (mu). mu = mucosa; oe = oesophagus; sm = sub-mucosa. B: †Axelrodichthys araripensis from the Cretaceous of Brazil, "Josa Collection" (specimen deposited at the MNHN, Paris). Transverse ground cross section of the calcified lung showing the imbricated plates (black arrow-heads) around the lumen (black asterisks) (after Clément, 1999: fig. 6). Scale bars: A = 1 mm; B = 5 mm. Deposited at the Laboratoire de Paléontologie, MNHN, Paris.

Fig. 5 in Repeated inoculations with the lung and heartworm nematode Angiostrongylus vasorum result in increasing larval excretion and worm burden in the red fox (Vulpes vulpes)

Fig. 5. Absolute counts of Eosinophils. The dotted horizontal lines represent reference ranges based on average values ± 2 × S.D. of values of foxes from groups A3, B and D at 0 wpi. Error bars (S.E.M).

Fig. 2 in Repeated inoculations with the lung and heartworm nematode Angiostrongylus vasorum result in increasing larval excretion and worm burden in the red fox (Vulpes vulpes)

Fig. 2. Arithmetic mean worm burden at necropsy per group. Foxes of groups A were inoculated once and necropsied at 9 wpi (A1), 13 wpi (A2) or 23 wpi (A3), while foxes of groups challenged once (B) or twice (D) and the control foxes of the first (C) and second challenge (E) were necropsied 23 wpi. Bar indicates mean with outlier excluded. Error bars = S.E.M.

Fig. 3 in Repeated inoculations with the lung and heartworm nematode Angiostrongylus vasorum result in increasing larval excretion and worm burden in the red fox (Vulpes vulpes)

Fig. 3. Arithmetic mean worm fecundity (expressed as final LPG/number female worms at necropsy) per group. Foxes of groups A were inoculated once and necropsied at 9 wpi (A1), 13 wpi (A2) or 23 wpi (A3), while foxes of groups challenged once (B) or twice (D) and the control foxes of the first (C) and second challenge (E) were necropsied 23 wpi. Bar indicates mean with outlier excluded. Error bars = S.E.M.

Fig. 1 in Repeated inoculations with the lung and heartworm nematode Angiostrongylus vasorum result in increasing larval excretion and worm burden in the red fox (Vulpes vulpes)

Fig. 1. Experimental design: inoculations with 100 third stage larvae (L3) of Angiostrongylus vasorum are indicated by triangles, challenge inoculations (also with 100 L3) by circles and the differing group termination times by squares.

Fig. 4 in Repeated inoculations with the lung and heartworm nematode Angiostrongylus vasorum result in increasing larval excretion and worm burden in the red fox (Vulpes vulpes)

Fig. 4. Arithmetic mean larval counts (first stage larvae per gram of feces) of foxes dogs experimentally inoculated at 0 wpi and challenged once (group B) or twice (group D) with 100 third stage larvae of Angiostrongylus vasorum from 6 to 22 wpi. Y-axis log10 transformed. Arrows indicate the challenge time points.

opencc-by-4.0Jan 2019View details →

Function of RORA in mouse lung inflammation

<p>This dataset contains microscopy images of mice lung, RORA KO vs wildtype. The mice were infected with N. brasiliensis.</p>

Fig. 14 in An Atlas Of Book Lung Fine Structure In The Order Scorpiones (Arachnida)

Fig. 14. Broteochactas delicatus (Karsch, 1879), 1 ³ (AMNH), KOH-macerated cuticle: dorsal view of attachment site of poststigmaticus muscle on posterior edge of book lung spiracle. Posterior edge normally closes spiracle unless pulled open by contraction of poststigmaticus muscle.

Fig. 11 in An Atlas Of Book Lung Fine Structure In The Order Scorpiones (Arachnida)

Fig. 11. Vaejovis spinigerus (Wood, 1863), 1 ³ (AMNH [LP 1811]): anterior view of posterior spiracle edge with transition to sternite and wall of atrium, anterior parts of sternite removed. Note change in shape of cuticular processes from flat-oval (box) to subconical structures on spiracle edge (character 3, denoted with arrowhead); a movable flap normally closes the spiracle unless pulled open by contraction of the poststigmaticus muscle. Inset: Urophonius iheringii Pocock, 1893, 1 ♀ (AMNH [LP 3457]): magnified posterior view of flat-oval processes on transition from spiracle edge to atrial wall.

Fig. 9 in An Atlas Of Book Lung Fine Structure In The Order Scorpiones (Arachnida)

Fig. 9. Broteochactas delicatus (Karsch, 1879), 1 ³ (AMNH), KOH-macerated cuticle: dorsal view of lateral part of sternite, showing cuticular parts of book lung.

Fig. 13 in An Atlas Of Book Lung Fine Structure In The Order Scorpiones (Arachnida)

Fig. 13. Euscorpius flavicaudis (DeGeer, 1778), 1 ex. (MNHN): internal view into lamella showing cellular pillar in hemolymph space.

Fig. 7 in An Atlas Of Book Lung Fine Structure In The Order Scorpiones (Arachnida)

Fig. 7. Hadogenes sp., 1 ³ (HUB): dorsolateral view of fenestrated membrane, covering sternite and book lung.

Fig. 6 in An Atlas Of Book Lung Fine Structure In The Order Scorpiones (Arachnida)

Fig. 6. Hadogenes sp., 1 ³ (HUB): ventral view of book lung, with fenestrated membrane removed, showing ligaments holding air sacs.

Fig. 4 in An Atlas Of Book Lung Fine Structure In The Order Scorpiones (Arachnida)

Fig. 4. Hottentotta jayakari (Pocock, 1895), 1 subad. ♀ (HUB): lateral view of longitudinal section through book lung, showing position of book lung morphology characters discussed in the atlas (arrowheads): lamellar surface (1); distal lamellar edge (2); posterior spiracle edge (3); (A–C) arrangement of characters in the plates, (A) lamellar surface, (B) distal lamellar edge, (C) posterior spiracle edge; arrowheads and arrows indicate characters and states.

Fig. 5. Cercophonius sulcatus Kraepelin, 1908, 1 in An Atlas Of Book Lung Fine Structure In The Order Scorpiones (Arachnida)

Fig. 5. Cercophonius sulcatus Kraepelin, 1908, 1 ³ (AMNH [LP 1618]): dorsal view of lateral part of sternite, illustrating shape of seven median air sacs of book lung.

Fig. 3. Brotheas granulatus Simon, 1877, 1 in An Atlas Of Book Lung Fine Structure In The Order Scorpiones (Arachnida)

Fig. 3. Brotheas granulatus Simon, 1877, 1 ³ (MNHN RS 8508): ventral view of dextral surface of sternite, showing position of spiracle, slanted with anterior margin (top) toward the midline (left).

Fig. 1. Euscorpius carpathicus candota Birula, 10-3 in An Atlas Of Book Lung Fine Structure In The Order Scorpiones (Arachnida)

Fig. 1. Euscorpius carpathicus candota Birula, 10-3: 1 f (HUB): diagrammatic representation of longitudinal histological section through book lung (foreground

Fig. 12. Euscorpius carpathicus candiota Birula, 1903, 1 in An Atlas Of Book Lung Fine Structure In The Order Scorpiones (Arachnida)

Fig. 12. Euscorpius carpathicus candiota Birula, 1903, 1 ♀ (HUB): lateral view of proximal parts of book lung (longitudinal section) showing lamellae and blind ends of air sacs.

opencc-by-4.0Oct 2022View details →

Single-cell and spatial transcriptomics delineate molecular traits and immunosuppressive landscape during histological progression of lung adenocarcinoma

<p>Two specimens of lung adenocarcinoma, each corresponding to the lepidic and solid histologic patterns as confirmed through histologic scrutiny, were procured in accordance with standard surgical protocols. These specimens underwent a process of formalin fixation and were subsequently encapsulated within paraffin-embedded tissue blocks. The specimens were then sectioned and subjected to hematoxylin and eosin (H&E) staining to facilitate subsequent imaging at a resolution of 40x (equivalent to 0.25 micron/pixel) via the use of Aperio GT450 scanners. The tissue slides were then conveyed to the Genomics core, where following the decoverslipping of the tissue, the Visium CytAssist device was employed to transfer transcriptomic probes from the original glass slides to capture areas on Visium slides measuring 11mm x 11mm. Comprehensive transcriptomic profiling was achieved post mRNA permeabilization, through poly(A) capture and probe hybridization. The resultant libraries were sequenced utilizing the Illumina Novaseq 6000, using paired-end sequencing with a read length of 150 base pairs.</p>