Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
4,090
datasets available to search
ShareScore release 0.7.1
Dataset results
4,090 results for “Protocol”
H-MAGMA Protocol
<p>This folder contains the full protocol needed to generate the variant-gene annotation file to run Hi-C Coupled MAGMA or H-MAGMA. In addition to the codes, we have included variant-gene annotation files for 28 tissue and cell types from Jung et al. 2019. We have updated portions of the code from our previous Zenodo upload under the DOI <a href="https://doi.org/10.5281/zenodo.5503877">https://doi.org/10.5281/zenodo.5503877</a></p>
Overview of PASTA Questionnaires: Physical Activity through Sustainable Transport Approaches (PASTA): protocol for a multi-centre, longitudinal study
<p>Overview of questionnaires used in the PASTA project (Physical Activity through Sustainable Transport Approaches (PASTA))</p> <p>English version</p>
Extracellular Vesicles Analysis in the COVID-19 Era: Insights on Serum Inactivation Protocols towards Downstream Isolation and Analysis
<p>Representative AFM images of the samples analyzed in the relative manuscript. Raw data just imported from the AFM multimode native format to the Gwyddion Open source data analysis software</p>
MR Gradient System Long-Term Stability Investigation and Protocol Optimization for Quality Control using Gradient Impulse Response Function (GIRF)
<p>The dataset of the abstract "MR Gradient System Long-Term Stability Investigation and Protocol Optimization for Quality Control using Gradient Impulse Response Function (GIRF)" for ISMRM 2022, London, UK. The data processing code with instructions could be found <a href="https://github.com/BRAIN-TO/girfISMRM2022">here</a>.</p> <p> </p> <p>Meas1.zip and Meas2.zip contain the first and the second measurements of the raw T2* decay signal acquired with the phantom-based method. Note that the coil dimension has been averaged to save data volume for demonstration purposes. This will lead to a lower SNR of the calculated output gradient and GIRF.</p> <p> </p> <p>CalculatedGIRF.zip provides the author's pre-calculated GIRFs using the data without coil averaging. This data is used for all the postprocessing (e.g. SNR and stability analysis, etc.) in the published abstract with the source code provided in the same Github repository.</p> <p> </p>
APPENDIX A - SEARCH PROTOCOLE AND PAPERS LIST - Cognitive Neuroscience's Transposition in STEAM Classroom: A Systematic Literature Review
<p>An integrative literature review was performed corresponding to PRISMA’ protocol in order to integrate issues over an innovative curriculum through cognitive sciences didactic transposition in STEAM classrooms. The search action was handled using various international databases. Each paper was selected alongside the PICO strategy and a defined selection criterion. Analysis of the literature between 2000 and 2021 is presented.</p>
Assessing the impacts of conservation volunteering on participant wellbeing: a review protocol
<p>Original search titles for the review : </p> <p>Assessing the impacts of conservation volunteering on participant wellbeing:</p> <p>a review protocol</p>
Ambient temperature CiPA dynamic hERG protocol dataset recorded on the SyncroPatch 384SE
<p><strong>Abstract </strong></p> <p>The Comprehensive in vitro Proarrhythmic Assay (CiPA) has promoted use of <em>in silico</em> models of drug effects on cardiac repolarization to improve proarrhythmic risk prediction. These models contain a pharmacodynamic component describing drug binding to hERG channels that required <em>in vitro</em> data for kinetics of block, in addition to potency, to constrain them. To date, development and validation has been undertaken using data from manual patch-clamp. The application of this approach at scale requires the development of a high-throughput, automated patch-clamp (APC) implementation. Here, we present a comprehensive analysis of the implementation of the Milnes, or CiPA dynamic protocol, on an APC platform, including quality control and data analysis. Kinetics and potency of block were assessed for bepridil, cisapride, terfenadine and verapamil with data retention/QC pass rate of 21.8% overall, or as high as 50.4% when only appropriate sweep lengths were considered for drugs with faster kinetics. The variability in IC<sub>50</sub> and kinetics between manual and APC was comparable to that seen between sites/platforms in previous APC studies of potency. Whilst the experimental success is less than observed in screens of potency alone, it is still significantly greater than manual patch. With the modifications to protocol design, including sweep length, number of repetitions, and leak correction recommended in this study, this protocol can be applied on APC to acquire data comparable to manual patch clamp.</p> <p><strong>Description</strong></p> <p>High-throughput patch clamp electrophysiology dataset acquired on Nanion SyncroPatch 384PE platform describing the potency and kinetics of drug block of hERG channels stably expressed in CHO cells. The voltage protocols used were 10 or 40 s 0mV steps with a 15s, -80mV inter-pulse intervals, repeated 5 or 10 times in the absence (control) and presence of drug. Drug was added and cells clamped at -80 mV for 4 minutes prior to recording to ensure drug equilibration prior to recording the onset (kinetics) of drug block. This dataset accompanies the paper titled '<strong>High throughput measurement of hERG drug block kinetics using the CiPA dynamic protocol' </strong>by Monique J. Windley, Jessica Farr, Clifford TeBay, Jamie I. Vandenberg and Adam P. Hill<strong>. </strong></p> <p><strong>File information</strong></p> <p>Raw and leak corrected files for individual plates run on the SyncroPatch 384PE</p> <p><strong>Folder naming convention</strong>: Plate identifier (6 digit date_user initials_plate number)_type of data (leak uncorrected raw / leak corrected).</p> <ul> </ul> <p><strong>Raw data </strong></p> <ul> <li><strong>File naming convention: </strong>Plate identifier (6 digit date_user initials_plate number)_well number</li> <li>Each raw data folder also contains a file named QC_plate identifier no. which contains information used for cell/patch and hERG current quality controls including seal resistance, series resistance, capacitance, baseline (average current at -80mV), average (average leak uncorrected current during last 100 ms of 0mV step). QC details are reported for each sweep along with the drug and concentration, with external and 0 M reported for control sweeps.</li> <li>Full SyncroPatch plates were not used for all runs, only applicable wells were included where partial plates were run (see plates 240719_MW1-3, 170719_MW1-3, 180719_MW1 and 291119_MW1)</li> </ul> <p><strong>Leak corrected data</strong></p> <ul> <li><strong>File naming convention:</strong> well number_drug_concentration in M_leak_correction</li> <li>Refer to folder for plate identifier number.</li> <li>Each folder containing leak corrected data also contains a file labelled 'percent block' which contains percentage block measurements for each leak correction file in the same folder as identified by the well number.</li> <li>Only files passing the first pass QC were leak corrected (>125 MOhm seal, <80 MOhm series, 10-200 pA capacitance, >-300 pA baseline, >50 pA hERG current size and <20% change in peak control current)</li> </ul> <p> </p>
Source Location Privacy Aware Routing Protocols Selection Results
<p>This is the dataset used to generate the results for the journal paper " A Decision Theoretic Framework for Selecting Source Location Privacy Aware Routing Protocols in Wireless Sensor Networks" at Future Generation Computer Systems (FGCS) 2018.</p> <p> </p> <p> </p>
Survey Protocol - A Metrics suite for End-to-End Microservice Test Coverage
<p>These survey is performed and reported in a paper titled "A Metrics suite for End-to-End Microservice Test Coverage".</p>
The Gambian Pertussis Study (GaPs) Protocol: Supplementary data
<p>Attached are the following documents related to the protocol on 'The impact of acellular pertussis vaccination in pregnancy on the immunogenicity of acellular versus whole-cell pertussis vaccines in infancy: A protocol for a phase IV randomised, controlled mother-infant pertussis vaccine trial (The Gambian Pertussis Study, GaPs, ClinicalTrials.gov NCT03606096'</p> <ol> <li>Data dictionaries for the maternal and infant clinic visits </li> <li>GaPs informed consent document for pregnant participants</li> <li>SPIRIT checklist - signed</li> <li>Independent data and safety monitoring charter</li> </ol>
An SI-traceable protocol for the validation of radiative transfer model-based reflectance simulation: datasets
<p>This data record contains datasets used in the study "An SI-traceable protocol for the validation of radiative transfer model-based reflectance simulation":</p> <ul> <li>The <code><span>final_design.ply</span></code> file contains the mesh corresponding to the final artefact design.</li> <li>The <code><span>material_measurements.nc</span></code> file contains goniophotometer records for the material reflectance.</li> <li>The <code><span>artefact_measurements.nc</span></code> file contains goniophotometer records for the artefact reflectance.</li> </ul>
Assessment of risk and vulnerability to disasters by field protocols and classification trees: an analysis of the Municipal Risk Reduction Plans (MRRP) of São Bernardo do Campo and Franco da Rocha (2020-2021), in Brazil
<p><span>Most disaster risk assessment methodologies were developed by natural science professionals. The UN Sendai Framework confirms the need to include these methods as interweaving complex networks of socially vulnerable financial processes, especially in developing countries. This work aimed to analyze the experience of including social vulnerability information in field protocols of the Municipal Risk Reduction Plans (MRRP) of São Bernardo do Campo and Franco da Rocha (2020-2021). A georeferenced database was structured with data from field protocols on risk sectors and then the relationship between vulnerability and risk was analyzed using the classification tree method. The results show that the geotechnical and social vulnerability variables relevant to risk attribution are largely overlapping over the sectors, but that the integrated analysis of the two dimensions allows a better interpretation of the risk level. However, the models with information from field protocols cannot replace a broader holistic assessment by the specialist in the field. Finally, qualitative reflections are made on the limitations and potential of including aspects of vulnerability in the specific case study.</span></p>
Figure 2 in EVALUATION OF THE EFFECTIVENESS OF USING A UNIVERSAL METHOD FOR ISOLATING GENOMIC dsDNA BY SALTING OUT TECHNIQUE ACCORDING TO THE S.M. ALJANABI AND I. MARTINEZ PROTOCOL FOR YEAST SACCHAROMYCES CEREVISIAE
Figure 2. Quantification of extracted Saccharomyces cerevisiae DNA by UVVis Spectrophotometry (DNA samples: 1–15).
Fig. 2 in Protocol Optimization For Genomic Dna Extraction And Rapd-Pcr Of Alien Ponto-Caspian Amphipod Pontogammarus Robustoides
Fig. 2. RAPD fingerprints results from different samples of Pontogammarus robustoides with primers OPA-02 (1-12 runners- different samples of Pontogammarus robustoides; K- control) using RAPD-PCR 10 × Taq buffer with KCl.
Fig. 3. Agarose gel image Fig. 4 in Optimization Of Dna Extraction Protocol For Dna Isolation From Air-Dried Collection Material For Further Phylogenetic Analysis (Coleoptera: Carabidae)
Fig. 3. Agarose gel image Fig. 4. Agarose gel image (successful PCR amplification) (failed PCR amplification) M: marker (bp) M: marker (bp) A1: Agonum fuliginosum Panzer, 1809 A: Agonum fuliginosum Panzer, 1809 A2: Agonum thoreyi Dejean, 1828 O: Omophron aequale aequale Morawitz, 1863 O: Omophron aequale aequale Morawitz, 1863 N: Notiophilus semistriatus Say, 1823 N: Notiophilus semistriatus Say, 1823 Nk: negative control. Nk: negative control.
Fig. 1 in Optimization Of Dna Extraction Protocol For Dna Isolation From Air-Dried Collection Material For Further Phylogenetic Analysis (Coleoptera: Carabidae)
Fig. 1. Photo of Omophron aequale jacobsoni Fig. 2. Photo of Omophron aequale jacobsoni Semenov, 1922 before incubation. Semenov, 1922 after 16 h (56°C) incubation time in tissue lysis buffer with proteinase K.
FIGURE A3-2. m1 images preparation protocol. A in Morphospace dynamics and intraspecies variety of Sorex araneus and S. tundrensis according to recent and fossil data
FIGURE A3-2. m1 images preparation protocol. A, Two-dimensional images of m1 give from three-dimensional model of a hemimandible. B, Interface MorphoDig software (Lebrun, 2020) for work with the models. C, Model alignment to the 'Functional View' in sense to Polly (2003), see details in Figure A3-3. D, Obtaining separate images via 'Snipping Tool' for three repeats, A, B, and C. E, Landmarking ready images via tpsDig software (Rohlf, 2007). F, Obtaining three separate data sets required for assessing the 'metering error' influence or obtaining a final work data set as a mean between repeats. Abbreviations: a, b — rotation along of the space planes for a model alignment.
Fig. 2 in Rearing protocol and density trials of the brown marmorated stink bug (Hemiptera: Pentatomidae) in the laboratory
Fig. 2. Mean (± SD) number of egg masses laid per female at densities of 1:1, 2:2, and 5:5 (female to male) per cage and mean (± SD) survival of females from first egg mass laid at densities of 1:1, 2:2, and 5:5 per cage
Fig. 1. Bug dorms. A in Rearing protocol and density trials of the brown marmorated stink bug (Hemiptera: Pentatomidae) in the laboratory
Fig. 1. Bug dorms. A. The large cage can house up to 12 bug dorms, with each stack containing 3 dorms. B. The large insect cage with humidifier attached. C. Stacks of Petri dishes. D. Humidifier.
Fig. 3 in A standardised faecal collection protocol for intestinal helminth egg counts in Asian elephants, Elephas maximus
Fig. 3. Pairwise comparisons of faecal egg counts (in EPG) for samples taken from different faecal boluses produced in one defecation event of (a) first and middle boluses, (b) first and last boluses, (c) middle and last boluses, all with 95% confidence intervals. For each of (a‾c) 40 samples collected from 20 elephants. Data collected for one elephant not shown, with one extreme data point removed in each of a‾c, to allow for better presentation of plots.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.