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ShareScore release 0.9.0
Dataset results
88 results for “Sampling bias”
Time of Day Bias for Biological Sampling in Studies of Mammary Cancer
GEO Series GSE249022. Mus musculus. 60 samples. Type: Other.
Data from: The effect of DNA degradation bias in passive sampling devices on metabarcoding studies of arthropod communities and their associated microbiota
PCR amplification bias is a well-known problem in metagenomic analysis of arthropod communities. In contrast, variation of DNA degradation rates is a largely neglected source of bias. Differential degradation of DNA molecules could cause underrepresentation of taxa in a community sequencing sample. Arthropods are often collected by passive sampling devices, like malaise traps. Specimens in such a trap are exposed to varying periods of suboptimal storage and possibly different rates of DNA degradation. Degradation bias could thus be a significant issue, skewing diversity estimates. Here, we estimate the effect of differential DNA degradation on the recovery of community diversity of Hawaiian arthropods and their associated microbiota. We use a simple DNA size selection protocol to test for degradation bias in mock communities, as well as passively collected samples from actual Malaise traps. We compare the effect of DNA degradation to that of varying PCR conditions, including primer choice, annealing temperature and cycle number. Our results show that DNA degradation does indeed bias community analyses. However, the effect of this bias is of minor importance compared to that induced by changes in PCR conditions. Analyses of the macro and microbiome from passively collected arthropod samples are thus well worth pursuing.
Clinical Evaluation of Tissue Sampling Bias in Histologic Evaluation of Sentinel Lymph Nodes in Breast Cancer
ClinicalTrials.gov study NCT01140763. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Single cell transcriptome level assessment of human platelet-biased hematopoietic stem cells isolated from bone marrow samples obtained from healthy young and old adult donors.
GEO Series GSE188889. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Data from: The effect of DNA degradation bias in passive sampling devices on metabarcoding studies of arthropod communities and their associated microbiota
Open the record for dataset details and reuse information.
Systematic Bias in Genomic Classification Due to Contaminating Normal Tissue in Breast Tumor Samples
GEO Series GSE22384. Homo sapiens. 118 samples. Type: Expression profiling by array.
Systematic Bias Introduced by Ficoll-Based Isolation in AML Sample Composition and Downstream Analyses
GEO Series GSE313042. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.
Reducing sampling bias in molecular studies of grapevine fruit ripening: transcriptomic assessment of the density sorting method
GEO Series GSE76000. Vitis vinifera. 43 samples. Type: Expression profiling by array.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.