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272
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ShareScore release 0.9.0
Dataset results
272 results for “childhood cancer”
A Web-Based Physical Activity Intervention in Adolescent Survivors of Childhood Cancer
ClinicalTrials.gov study NCT01778127. IPD Sharing: Not stated. Countries: 1. Publications: 0.
An Open-Label Pilot Intervention Trial to Prevent Diabetes in Prediabetic Adult Survivors of Childhood Cancer
ClinicalTrials.gov study NCT04742751. IPD Sharing: YES. Countries: 1. Publications: 0.
Mobile Health Fitness Program for Adolescent and Young Adult Childhood Cancer Survivors
ClinicalTrials.gov study NCT02688192. IPD Sharing: NO. Countries: 1. Publications: 0.
Analyzing Childhood Recall Antigens in Patients With Pancreatic Cancer
ClinicalTrials.gov study NCT03848182. IPD Sharing: NO. Countries: 1. Publications: 0.
Mindfulness Interventions to Improve Health Activation, Coping, and Stress Among Childhood Cancer Survivors
ClinicalTrials.gov study NCT06053268. IPD Sharing: YES. Countries: 1. Publications: 0.
An Open-Label Intervention Trial to Reduce Senescence and Improve Frailty in Adult Survivors of Childhood Cancer
ClinicalTrials.gov study NCT04733534. IPD Sharing: YES. Countries: 1. Publications: 0.
Virtual Exercise Training and Its Impact on Bone Compartments in Adult Survivors of Childhood Cancer
ClinicalTrials.gov study NCT07022262. IPD Sharing: YES. Countries: 1. Publications: 0.
Data from: Endocrine and metabolic disorders in survivors of childhood cancers and health-related quality of life and physical activity
Open the record for dataset details and reuse information.
Genome-wide association studies identify novel genetic loci for epigenetic age acceleration among survivors of childhood cancer [Metadata_SJLIFE2_502]
GEO Series GSE197675. Homo sapiens. 502 samples. Type: Methylation profiling by genome tiling array.
Mouse hepatoblastoma models with expression of mutant β-catenin and/or c-Myc for therapeutic target identification of childhood liver cancer
GEO Series GSE79084. Mus musculus. 11 samples. Type: Expression profiling by array.
An Organoid Biobank for Childhood Kidney Cancers that Captures Disease and Tissue Heterogeneity
GEO Series GSE137544. Homo sapiens. 45 samples. Type: Methylation profiling by genome tiling array.
Genome-wide association studies identify novel genetic loci for epigenetic age acceleration among survivors of childhood cancer [Metadata_SJLIFE_controls_282]
GEO Series GSE197676. Homo sapiens. 282 samples. Type: Methylation profiling by genome tiling array.
Epigenome-wide DNA Methylation Profiling in the Investigation of Treatment and Life-Course Exposures and Adverse Health Outcomes in Survivors of Childhood Cancer from the St. Jude Lifetime Cohort
GEO Series GSE314261. Homo sapiens. 5013 samples. Type: Methylation profiling by genome tiling array.
Haptoglobin Gene Expression and Anthracycline-related Cardiomyopathy in Childhood Cancer Survivors
GEO Series GSE218276. Homo sapiens. 104 samples. Type: Expression profiling by high throughput sequencing.
Lifestyle and subsequent meningioma in childhood cancer survivors: A report from the St. Jude Lifetime Cohort study
<p>nomrn_1rowid : is file for getting the descriptive for the study. </p> <p>rows_perdid : After the data above was ran through ageyear macro for piecewise exponential model. </p>
Temporal changes in treatment and late mortality and morbidity in adult survivors of childhood glioma: a report from the Childhood Cancer Survivor Study
<p><strong>Abstract:</strong></p> <p>Pediatric glioma therapy has evolved to delay or eliminate radiation for low-grade tumors. This study examined these temporal changes in therapy with long-term outcomes in adult survivors of childhood glioma. Among 2,501 5-year survivors of glioma in the Childhood Cancer Survivor Study diagnosed 1970–1999, exposure to radiation decreased over time. Survivors from more recent eras were at lower risk of late mortality (≥5 years from diagnosis), severe/disabling/life-threatening chronic health conditions (CHCs) and subsequent neoplasms (SNs). Adjusting for treatment exposure (surgery only, chemotherapy, or any cranial radiation) attenuated this risk (for example, CHCs (1990s versus 1970s), relative risk (95% confidence interval), 0.63 (0.49–0.80) without adjustment versus 0.93 (0.72–1.20) with adjustment). Compared to surgery alone, radiation was associated with greater than four times the risk of late mortality, CHCs and SNs. Evolving therapy, particularly avoidance of cranial radiation, has improved late outcomes for childhood glioma survivors without increased risk for late recurrence.</p>
Hypogonadism and Neurocognitive Outcomes among Childhood Cancer Survivors
<h2>Abstract</h2> <div> <div><strong>Objective</strong></div> <p>Childhood cancer survivors are at risk for hypogonadism. Impact of hypogonadism on neurocognitive impairment and emotional distress in the non-cancer population has been shown, however, the relationship among childhood cancer survivor population is unknown. We aimed to evaluate the contribution of hypogonadism to neurocognitive impairment and emotional distress among survivors.</p> </div> <div> <div><strong>Design</strong></div> <p>Cross-sectional study using retrospective cohort.</p> </div> <div> <div><strong>Methods</strong></div> <p>3628 survivors who completed standard neurocognitive tests (six domains: processing speed, memory, executive function, attention, academics, global cognition) and self-reported emotional distress were included in our study. Participants were stratified by sex and gonadal status. Outcomes were compared between hypogonadal and eugonadal groups by multivariable analysis, adjusting for established predictors, and mediation analyses to determine the direct/indirect effects of hypogonadism on outcomes.</p> </div> <div> <div><strong>Results</strong></div> <p>The hypogonadal group exhibited higher prevalence of neurocognitive impairment across domains, but no difference in emotional distress. Hypogonadal females exhibited higher relative risk (1.7, 95% confidence interval 1.2–2.5) for impaired visual processing speed, compared to eugonadal females after adjusting for cancer-related variables. In mediation models, hypogonadism had significant direct (<em>P</em> < 0.01) and indirect (from <em>P</em> < 0.01) impact on impairment in visual processing speed among females. Males demonstrated direct (<em>P</em> =0.03) and indirect (<em>P</em> =0.04) impact of hypogonadism on motor processing speed.</p> </div> <div> <div><strong>Conclusion</strong></div> <p>Processing speed may be the most vulnerable neurocognitive domain associated with hypogonadism in survivors, while other domains were mainly impacted by cancer-related variables. Our findings support the need for further evaluation of the impact of sex hormone replacement therapy on neurocognitive function.</p> </div>
Neurologic morbidity and functional independence in adult survivors of childhood cancer
<p>SAS data set "<span><a href="../api/records/10878104/draft/files/neuro_morbi_indep.sas7bdat/content" target="_blank" rel="noopener noreferrer">neuro_morbi_indep.sas7bdat</a></span>" contains data for publication "Neurologic morbidity and functional independence in adult survivors of childhood cancer". Variables and formats are in the file "<span><a href="../api/records/10878104/draft/files/Variables%20and%20formats%20for%20neuro_morbi_indep.docx/content" target="_blank" rel="noopener noreferrer">Variables and formats for neuro_morbi_indep.docx</a></span>".</p>
Risk factors for neurocognitive impairment, emotional distress, and poor quality of life in survivors of pediatric rhabdomyosarcoma: A report from the Childhood Cancer Survivor Study
<p>Dataset contains all variables used in the manuscript. </p> <p>Variable name file describes the variable names in details.</p>
Health behavior profiles in young survivors of childhood cancer: Findings from the St. Jude Lifetime Cohort Study
<p>The dataset contains all variables of interest presented in the study. By downloading and using these data, you agree that you will cite the appropriate publication in any communications or publications arising directly or indirectly from these data; for utilization of data available prior to publication, you agree to respect the requested responsibilities of resource users under 2003 Fort Lauderdale principles; you agree that you will never attempt to identify any participant. </p> <p><strong>When using downloaded data, please cite corresponding paper and this repository:</strong></p> <p>Webster, Rachel Tillery, et al. “Health Behavior Profiles in Young Survivors of Childhood Cancer: Findings from the St. Jude Lifetime Cohort Study.” <em>Cancer</em>, 2023, https://doi.org/10.1002/cncr.34749.</p> <p><strong>Data dictionary:</strong></p> <p>Status: Participation Status<br> dept: Depression T score<br> anxt: Anxiety T score<br> paint: Pain T score<br> gender: Gender<br> race: Race<br> grp: Diagnosis group<br> eth: Ethnicity<br> liquidtumor: Liquid tumor flag<br> grp2: Diagnosis group 2<br> homeinc: Last year household income<br> agesurvey: Age at survey<br> relation: Relationship to participant<br> chemoagt_any: Any chemotherapy agent flag<br> surgery_trt: Any Surgery (within 3mo pre -> 5yrs post treatment window)<br> AnyRT: Any radiation therapy flag<br> agedx: Age at diagnosis<br> ageffq: Age at functional assessment<br> Class2: 2 latent classes<br> white: Race - "White"<br> over60: Income over USD 60000$<br> hins: Health insurance<br> hsorless: Highschool or lesser education<br> grade34: CTCAE grade 3/4 for any condition<br> Leukemia: Leukemia flag<br> CNS: CNS tumor <br> BOT2PERCRANK: Motor Proficiency: Percentile rank (BOT-2)<br> rhravg: Resting heart-rate average<br> respavg: Average respirations<br> PCI: Physiological cost index<br> Exertion: Physical activity exertion<br> bmipct: BMI-for-age percentile<br> avgsbp: Average Systolic BP<br> avgdbp: Average Diastolic BP<br> pbf: Percent body fat<br> Class4: 4 latent classes<br> number: Serial number<br> </p>
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.