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142 results for “coinfections”
Quality over quantity: unraveling the contributions to cytoplasmic incompatibility caused by two coinfecting Cardinium symbionts
<p><i>Cardinium hertigii</i> is a common maternally-inherited bacterial endosymbiont of arthropods. Some <i>Cardinium</i> strains spread by increasing female fitness through the induction of cytoplasmic incompatibility (CI), which kills offspring of crosses between infected males and uninfected female hosts. CI is a two-step manipulation: first, sperm from male hosts are modified by the symbiont in a manner that causes offspring death. Second, when females are also infected, the symbiont reverses sperm modification in the egg cytoplasm, allowing offspring of infected females to survive and spread the symbiont. While <i>Cardinium</i> causes CI in many arthropod hosts, most of what is known about <i>Cardinium</i> CI stems from the symbiosis between the <i>Cardinium</i> strain <i>c</i>Eper1 and its minute parasitoid host, <i>Encarsia suzannae</i>. Here, we study a second <i>Cardinium</i> CI system in the wasp <i>Encarsia partenopea</i>. <i>Encarsia partenopea</i> harbors two <i>Cardinium</i> strains, <i>c</i>Eina2 and <i>c</i>Eina3, with the <i>c</i>Eina3 present at a much lower density than <i>c</i>Eina2. Using antibiotic treatments and crossing assays, we find that the low-density <i>c</i>Eina3 strain is responsible for CI, and that <i>c</i>Eina3 appears to modify sperm during the pupal stage, like the better known <i>c</i>Eper1. However, <i>c</i>Eina3 shows a markedly different localization pattern in male reproductive tissues. Instead of infecting sperm cells, <i>c</i>Eina3 is found in somatic cells at the base of the testis and around the seminal vesicle. This localization pattern suggests that <i>c</i>Eina3 may use a different sperm modification strategy from <i>c</i>Eper1, and highlights variation between these closely related symbioses.</p>
Hepatic Safety of Raltegravir Versus Efavirenz as HIV Therapy for Patients With HIV and HCV Coinfection
ClinicalTrials.gov study NCT01147107. IPD Sharing: YES. Countries: 1. Publications: 0.
B/F/TAF Switch Study for HIV-HBV Coinfection
ClinicalTrials.gov study NCT03797014. IPD Sharing: NO. Countries: 1. Publications: 0.
Safety and Antiviral Activity of TPV in HCV and/or HBV HIV Coinfected Patients TDM Randomised Pilot Evaluation
ClinicalTrials.gov study NCT00447902. IPD Sharing: Not stated. Countries: 7. Publications: 0.
A Study to Treat Subjects With Telaprevir, Ribavirin, and Peginterferon Who Are Coinfected With HIV and Hepatitis C Virus (HCV)
ClinicalTrials.gov study NCT01467479. IPD Sharing: Not stated. Countries: 5. Publications: 0.
NATURAL HISTORY-Hepatitis C Virus/ Human Immunodeficiency Virus Coinfection
ClinicalTrials.gov study NCT00315432. IPD Sharing: Not stated. Countries: 0. Publications: 1.
A Prospective, Longitudinal Study of Endothelial Function in HIV/HCV Coinfected Subjects
ClinicalTrials.gov study NCT02597790. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Sofosbuvir Based DAA Therapy in HIV/HCV Coinfected Pre or Post Liver Transplant
ClinicalTrials.gov study NCT02533934. IPD Sharing: NO. Countries: 1. Publications: 0.
Status of Chronic Liver Disease in Hepatitis C Virus (HCV) Patients Coinfected With Human Immunodeficiency Virus (HIV) in Andalusia
ClinicalTrials.gov study NCT02511496. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Effectiveness of Raltegravir-Based Antiretroviral Therapy in HIV-HCV Coinfected Liver Transplant Recipients
ClinicalTrials.gov study NCT02995824. IPD Sharing: NO. Countries: 0. Publications: 8.
HIV-1 & Coronavirus-Coinfection in Europe: Morbidity & Risk Factors of COVID-19 in People Living With HIV
ClinicalTrials.gov study NCT05481216. IPD Sharing: NO. Countries: 5. Publications: 0.
Interactions of Hepatitis C Viral (HCV) Dynamics and Immune Activation in HIV Coinfected Patients During HCV Treatment
ClinicalTrials.gov study NCT00909129. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Data from: Using multi-response models to investigate pathogen coinfections across scales: insights from emerging diseases of amphibians
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Data from: Coinfection outcome in an opportunistic pathogen depends on the inter-strain interactions
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Quality over quantity: unraveling the contributions to cytoplasmic incompatibility caused by two coinfecting Cardinium symbionts
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Data from: Reciprocal interaction matrix reveals complex genetic and dose-dependent specificity among coinfecting parasites
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Social immunity modulates competition between coinfecting pathogens
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Data from: Life‐history correlations change under coinfection leading to higher pathogen load
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Data from: Frequent coinfection reduces RNA virus population genetic diversity
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Data from: Antibodies and coinfection drive variation in nematode burdens in wild mice
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.