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1,248 results for “epithelium”
Measurement and Analysis of Macular Retinal Pigment Epithelium (RPE) Elevations With Cirrus HD-OCT vs. Color Fundus Photography
ClinicalTrials.gov study NCT01272063. IPD Sharing: Not stated. Countries: 1. Publications: 9.
Epi-LASIK : A Confocal Microscopy Analysis of the Corneal Epithelium and Anterior Stroma.
ClinicalTrials.gov study NCT00599690. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Biohybrid microrobots regulate colonic cytokine and epithelium barrier in inflammatory bowel disease
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Lung distal epithelium ChiaRed and WT epithelial cells
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Data from: The presence of bacterial microcolonies on the maxillary sinus ciliary epithelium in healthy young individuals
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Data from: Oxidative stress in the retina and retinal pigment epithelium (RPE): role of aging, and DJ-1
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BMP/SMAD1/5 signaling in the endometrial epithelium is essential for receptivity and early pregnancy
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Fig. 3 in Metaplasia in swim bladder epithelium of the endangered annual fish Austrolebias nigrofasciatus (Cyprinodontiformes: Rivulidae) results in inadequate swimming and delayed growth
Fig. 3. Histological section (HE) of Austrolebias nigrofasciatus seven days after hatching with the swim bladder (SB) inflated up to 24 hours after hatching. a. SB filled with gas; b. SB inflated and SB desquamated epithelial cells in the lumen (arrows); c. SB inflated with sectoral epithelial metaplasia (arrow). Scale = 100 micrometres.
Fig. 2 in Metaplasia in swim bladder epithelium of the endangered annual fish Austrolebias nigrofasciatus (Cyprinodontiformes: Rivulidae) results in inadequate swimming and delayed growth
Fig. 2. Effect of the swim bladder dysfunction in the initial growth of Austrolebias nigrofasciatus. Groups: normal fish (inflated bladder), belly-sliders (uninflated bladder) and re- verted to the normal condition (reversed). Different letters represent significantly differences between means (Tukey test; p <0.05).
Fig. 1 in Metaplasia in swim bladder epithelium of the endangered annual fish Austrolebias nigrofasciatus (Cyprinodontiformes: Rivulidae) results in inadequate swimming and delayed growth
Fig. 1. Newly hatched Austrolebias nigrofasciatus with the inflated swim bladder (a) and with the vesicle not inflated (i.e., belly-slider) (b). Grey arrow indicates location of swim bladder. Scale = 1 mm.
Fig. 4 in Metaplasia in swim bladder epithelium of the endangered annual fish Austrolebias nigrofasciatus (Cyprinodontiformes: Rivulidae) results in inadequate swimming and delayed growth
Fig. 4. Histological section (HE) of belly-sliders of Austrolebias nigrofasciatus with uninflated swim bladder (SB) 14 days after hatching. Grey arrow – SB epithelial cells peeling; white arrow – erythrocytes indicating bleeding; black arrow – meta- plasia of the SB epithelium. Scale = 100 micrometres.
Characteristics of non-neoplastic epithelium that appears within gastric cancer with and without Helicobacter pylori eradication
<p>A non-neoplastic epithelium (NE) often appears in gastric cancer (GC). We explored the histological features of NE in comparison between HP-eradicated and HP-infected GCs.<b> </b>We enrolled 40 HP-eradicated and 40 HP-infected GCs matched by size, macroscopic and histological type. NE was classified into full gland type and surface type; the former was a non-neoplastic gland isolated within cancer, and the latter was NE on the surface of the cancer. Surface type was additionally divided into NE at the cancer margin (marginal surface type) and NE inside cancer (internal surface type). The primary endpoints were the frequency and the length ratio (the ratio to cancer length) of NE in each GC. The secondary endpoints were the relationships between NE and clinicopathological factors, including endoscopic findings of a gastritis-like appearance (GLA), multiple white elevated lesions (MWELs), reddish depressed lesion (RDL), and white nodular mucosa (WNM).<b> </b>The frequency and length ratio of the internal surface type in HP-eradicated GCs were significantly higher (82.5% vs 50%, <i>P</i> = 0.005) and larger (11.6 ± 10.6 vs 4.2 ± 9.9, P < 0.001) than those in HP-infected GCs. The frequency and length ratio of marginal surface type and full gland type were not significantly different between the two GC groups, but the coexistence of internal surface and full gland types was statistically significant (p < 0.001). The frequencies of GLA, RDLs, and WNM in HP-eradicated GCs were significantly higher than those in HP-infected GCs. Moreover, GLA-positive GCs were covered more widely by internal surface type than GLA-negative GCs (13.3% vs. 6.6%, <i>P</i> = 0.003).<b> </b>Various types of NE were noted in gastric cancer, and the internal surface type of NE was shown to be significantly linked to HP-eradicated cancer and GLA.</p>
Data from: Human retinal pigment epithelium: in vivo cell morphometry, multispectral autofluorescence, and relationship to cone mosaic
Purpose: To characterize in vivo morphometry and multispectral autofluorescence of the retinal pigment epithelial (RPE) cell mosaic and its relationship to cone cell topography across the macula. Methods: RPE cell morphometrics were computed in regularly spaced regions of interest (ROIs) from contiguous short-wavelength autofluorescence (SWAF) and photoreceptor reflectance images collected across the macula in one eye of 10 normal participants (23–65 years) by using adaptive optics scanning light ophthalmoscopy (AOSLO). Infrared autofluorescence (IRAF) images of the RPE were collected with AOSLO in seven normal participants (22–65 years), with participant overlap, and compared to SWAF quantitatively and qualitatively. Results: RPE cell statistics could be analyzed in 84% of SWAF ROIs. RPE cell density consistently decreased with eccentricity from the fovea (participant mean ± SD: 6026 ± 1590 cells/mm2 at fovea; 4552 ± 1370 cells/mm2 and 3757 ± 1290 cells/mm2 at 3.5 mm temporally and nasally, respectively). Mean cone-to-RPE cell ratio decreased rapidly from 16.6 at the foveal center to <5 by 1 mm. IRAF revealed cells in six of seven participants, in agreement with SWAF RPE cell size and location. Differences in cell fluorescent structure, contrast, and visibility beneath vasculature were observed between modalities. Conclusions: Improvements in AOSLO autofluorescence imaging permit efficient visualization of RPE cells with safe light exposures, allowing individual characterization of RPE cell morphometry that is variable between participants. The normative dataset and analysis of RPE cell IRAF and SWAF herein are essential for understanding microscopic characteristics of cell fluorescence and may assist in interpreting disease progression in RPE cells.
Data from: Calcium transfer across the outer mantle epithelium in the Pacific oyster, Crassostrea gigas
Calcium transport is essential for bivalves to be able to build and maintain their shells. Ionized calcium (Ca2+) is taken up from the environment and eventually transported through the outer mantle epithelium (OME) to the shell growth area. However, the mechanisms behind this process are poorly understood. The objective of the present study was to characterize the Ca2+ transfer performed by the OME of the Pacific oyster, Crassostrea gigas, as well as to develop an Ussing chamber technique for the functional assessment of transport activities in epithelia of marine bivalves. Kinetic studies revealed that the Ca2+ transfer across the OME consists of one saturable and one linear component, of which the saturable component fits best to Michaelis–Menten kinetics and is characterized by a Km of 6.2 mM and a Vmax of 3.3 nM min−1. The transcellular transfer of Ca2+ accounts for approximately 60% of the total Ca2+ transfer across the OME of C. gigas at environmental Ca2+ concentrations. The use of the pharmacological inhibitors: verapamil, ouabain and caloxin 1a1 revealed that voltage-gated Ca2+-channels, plasma-membrane Ca2+-ATPase and Na+/Ca2+-exchanger all participate in the transcellular Ca2+ transfer across the OME and a model for this Ca2+ transfer is presented and discussed.
A systems biology approach to investigate glucocorticoid response in a cellular model of human bronchial epithelium - Supplementary material
<p>Electronic appendices of PhD thesis: "A systems biology approach to investigate glucocorticoid response in a cellular model of human bronchial epithelium".</p>
Intracellular and secreted proteome data from stressed human retinal pigmented epithelium tissues.
<p>Supporting tables for manuscript submission. </p>
Retinal and Retinal Pigment Epithelium (RPE) Autoimmunity in Age-related Macular Degeneration (AMD)
ClinicalTrials.gov study NCT00931489. IPD Sharing: NO. Countries: 1. Publications: 0.
Coherence Imaging of the Cervical Epithelium
ClinicalTrials.gov study NCT02903394. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Coherence Imaging of the Cervical Epithelium With Scanning a/LCI
ClinicalTrials.gov study NCT03502798. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Clinical Study to Evaluate CryoBalloon™ Full and Swipe Ablation Systems for Ablation of Human Esophageal Epithelium
ClinicalTrials.gov study NCT02729753. IPD Sharing: NO. Countries: 1. Publications: 0.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.