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208
datasets available to search
ShareScore release 0.9.0
Dataset results
208 results for “fatty acid metabolism”
The inhibition of inner mitochondrial fusion in hepatocytes reduces non-alcoholic fatty liver and improves metabolic profile during obesity by modulating bile acid conjugation
GEO Series GSE217644. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
PTHrP regulates fatty acid metabolism via novel lncRNA in breast cancer initiation and progression models
GEO Series GSE225877. Mus musculus. 33 samples. Type: Expression profiling by high throughput sequencing.
De novo transcriptome assembly of the five major organs of Zanthoxylum armatum and the identification of genes involved in terpenoid compounds and fatty acids metabolism
GEO Series GSE142491. Zanthoxylum armatum. 15 samples. Type: Expression profiling by high throughput sequencing.
Myeloid Fatty Acid Metabolism Activates Neighboring Hematopoietic Stem Cells to Fuel Heart Failure with Preserved Ejection Fraction
GEO Series GSE288048. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
A comprehensive evaluation of metabolically engineered Cynara cardunculus calli as platform for valuable fatty acid derivatives production
GEO Series GSE284690. Cynara cardunculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Metabolic reprogramming from fatty acid oxidation to glycolysis in a patient mutation knock-in mouse model of Barth Syndrome.[mouse]
GEO Series GSE221662. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
SGLT2 inhibitor upregulates myocardial genes for oxidative phosphorylation and fatty acid metabolism in Gαq mice (genotype x timepoint)
GEO Series GSE276289. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
BMP-dependent mobilization of fatty acid metabolism promotes Caenorhabditis elegans survival on a bacterial pathogen
GEO Series GSE291387. Caenorhabditis elegans. 12 samples. Type: Expression profiling by high throughput sequencing.
Fasciola hepatica Fatty Acid Binding Protein 1 modulates T cell polarization by promoting dendritic cell thrombospondin-1 secretion without affecting metabolic homeostasis in obese mice
GEO Series GSE197462. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Low-density lipoprotein receptor-5 contributes to whole body metabolism by regulating fatty acid metabolism in the osteoblast
GEO Series GSE55900. Mus musculus. 8 samples. Type: Expression profiling by array.
SCD2-mediated monounsaturated fatty acid metabolism regulates cGAS-STING-dependent type I IFN in mouse CD4+ T cells
GEO Series GSE173728. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism [RNA-Seq]
GEO Series GSE147770. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
Early weaning induces programmed obesity in rats at adulthood through impairing fatty acid β-oxidation and cholesterol metabolism, which can be mitigated by leucine supplementation
GEO Series GSE203486. Rattus norvegicus. 21 samples. Type: Expression profiling by high throughput sequencing.
Targeting fatty acid metabolism to abrogate differentiation block in pre-leukemia induced by AML1-ETO
GEO Series GSE270447. Mus musculus. 14 samples. Type: Expression profiling by high throughput sequencing.
A novel TetR-like transcriptional regulator in Stenotrophomonas maltophilia is involved in fatty acid metabolism, including quorum sensing signal turnover
GEO Series GSE206554. Stenotrophomonas maltophilia K279a. 6 samples. Type: Expression profiling by high throughput sequencing.
Novel pan-ERR agonists ameliorate heart failure through enhancing cardiac fatty acid metabolism and mitochondrial function
GEO Series GSE239912. Mus musculus; Rattus norvegicus. 30 samples. Type: Expression profiling by high throughput sequencing.
The interplay between dietary fatty acids and gut microbiota influences host metabolism and hepatic steatosis
GEO Series GSE222060. Mus musculus. 79 samples. Type: Expression profiling by array.
Sex-Dependent Programming of Glucose and Fatty Acid Metabolism in Mouse Offspring by Maternal Protein Restriction
GEO Series GSE15940. Mus musculus. 32 samples. Type: Expression profiling by array.
A Novel Alzheimer's Disease Drug Candidate Targeting Inflammation and Fatty Acid Metabolism
GEO Series GSE93678. Mus musculus. 13 samples. Type: Expression profiling by high throughput sequencing.
Data from: Tang-Nai-Kang alleviates pre-diabetes and metabolic disorders by inducing a gene expression switch toward fatty acid oxidation in SHR.Cg-Leprcp ⁄NDmcr rats
Increased energy intake and reduced physical activity can lead to obesity, diabetes and metabolic syndrome. Transcriptional modulation of metabolic networks has become a focus of current drug discovery research into the prevention and treatment of metabolic disorders associated with energy surplus and obesity. Tang-Nai-Kang (TNK), a mixture of five herbal plant extracts, has been shown to improve abnormal glucose metabolism in patients with pre-diabetes. Here, we report the metabolic phenotype of SHR.Cg-Leprcp/NDmcr (SHR/cp) rats treated with TNK. Pre-diabetic SHR/cp rats were randomly divided into control, TNK low-dose (1.67 g/kg) and TNK high-dose (3.24 g/kg) groups. After high-dose treatment for 2 weeks, the serum triglycerides and free fatty acids in SHR/cp rats were markedly reduced compared to controls. After 3 weeks of administration, the high dose of TNK significantly reduced the body weight and fat mass of SHR/cp rats without affecting food consumption. Serum fasting glucose and insulin levels in the TNK-treated groups decreased after 6 weeks of treatment. Furthermore, TNK-treated rats exhibited obvious improvements in glucose intolerance and insulin resistance. The improved glucose metabolism may be caused by the substantial reduction in serum lipids and body weight observed in SHR/cp rats starting at 3 weeks of TNK treatment. The mRNA expression of NAD+-dependent deacetylase sirtuin 1 (SIRT1) and genes related to fatty acid oxidation was markedly up-regulated in the muscle, liver and adipose tissue after TNK treatment. Furthermore, TNK promoted the deacetylation of two well-established SIRT1 targets, PPARγ coactivator 1α (PGC1α) and forkhead transcription factor 1 (FOXO1), and induced the phosphorylation of AMP-activated protein kinase (AMPK) and acetyl-CoA carboxylase (ACC) in different tissues. These observations suggested that TNK may be an alternative treatment for pre-diabetes and metabolic syndrome by inducing a gene expression switch toward fat oxidation through the activation of SIRT1 and AMPK signaling.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.