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101 results for “levels of selection”
Data from: A framework for detecting natural selection on traits above the species level
To what extent can natural selection act on groupings above the species level? Despite extensive theoretical discussion and growing practical concerns over increased rates of global ecological turnover, the question has largely evaded empirical resolution. A flexible and robust hypothesis-testing framework for detecting the phenomenon could facilitate significant progress in resolving this issue. We introduce a permutation-based approach, implemented in the R package perspectev, which provides an explicit test of whether empirical patterns of correlation between upper level trait values and survivorship are reducible to correlations manifested at lower levels. The package is applicable to virtually any nested set of upper- and lower level groupings, a wide variety of upper level traits, and both historical and contemporary occurrence data. We apply this approach to five paleontological data sets that represent different magnitudes of extinction and differ in taxonomic breadth, geological timing and geographic extent. Using simulations, we demonstrate that this method is a robust means of detecting irreducibility in the relationship between upper level traits and survivorship, and outline circumstances in which the method is less effective. We also find evidence consistent with previous findings of selection above the species level for geographic range size in North American K-Pg molluscs and show that this phenomenon was evident for the same molluscan genera globally. Ultimately, we conclude that at certain points in history, some higher level taxonomic groups have survived differentially with respect to geographic range size in a manner that is not explained by the same trait at the species level, and we show that evidence for this phenomenon varies across taxa and extinction events. We release our method as a flexible and easy-to-use R package that will allow others to help determine the relative frequency of this macroevolutionary phenomenon, both in the fossil record and in estimates of contemporary extinction risk.
Evaluation of selected serum biomarkers levels in response to infliximab reference product (Remicade®) versus it's biosimilar (Remsima®) in a sample of ulcerative colitis patients: a cross-sectional study
<p><strong>Evaluation of selected serum biomarkers levels in response to infliximab reference product (Remicade</strong><sup>®</sup><strong>) versus it's biosimilar (Remsima</strong><sup>®</sup><strong>) in a sample of ulcerative colitis patients: a cross-sectional study</strong></p>
Comparison of the Effects of Standardized Chokeberry Extracts With Various Formulations on the Levels of Selected Markers Associated With Cardiovascular Disease
ClinicalTrials.gov study NCT05988099. IPD Sharing: NO. Countries: 1. Publications: 0.
Selective Adjuvant Therapy for HPV-mediated Oropharynx SCCs Based on Residual Circulating Tumor DNA Levels (SAVAL)
ClinicalTrials.gov study NCT06088381. IPD Sharing: Not stated. Countries: 1. Publications: 0.
EFFECT OF SELECTIVE COX-2 INHIBITOR (ETORICOXIB) ALONG WITH SCALING AND ROOT PLANING (SRP) ON CLINICAL PARAMETERS AND SALIVARY LEVEL OF SUPEROXIDE DISMUTASE IN CHRONIC GENERALIZED PERIODONTITIS A DOUB
ClinicalTrials.gov study NCT02149758. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Evaluating the Rationality of the International Guideline About Selective Coverage of Level Ib in CTV With NPC
ClinicalTrials.gov study NCT04745741. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Effects of Selected Statins on Blood Glucose Levels in Healthy Volunteers
ClinicalTrials.gov study NCT07378293. IPD Sharing: YES. Countries: 1. Publications: 0.
Using Drug Levels and Drug Resistance Testing to Select Effective Anti-HIV Drug Combinations in Patients With Drug-resistant HIV
ClinicalTrials.gov study NCT00027339. IPD Sharing: Not stated. Countries: 2. Publications: 0.
Inheritance of gene expression level and selective constraints on trans- and cis-regulatory changes in yeast
GEO Series GSE46838. Saccharomyces cerevisiae. 4 samples. Type: Expression profiling by high throughput sequencing.
Data from: A framework for detecting natural selection on traits above the species level
Open the record for dataset details and reuse information.
Transcriptional profile in low to high-level macrolide resistant C. jejuni strain selected from NCTC 11168
GEO Series GSE17881. Campylobacter jejuni. 24 samples. Type: Expression profiling by array.
Genome-wide mapping of human DNA-replication origins: levels of transcription at Orc1 sites regulate origin selection and replication timing
GEO Series GSE37583. Homo sapiens. 13 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Mutations of the selected strain growing in low levels of Vitamin B12 in Mycobacterium marinum
GEO Series GSE240448. Mycobacterium marinum M. 6 samples. Type: Expression profiling by high throughput sequencing.
TMC435-TiDP16-C107: This Study Measures the (Possible) Influence of TMC435 on the Activity of a Selected Set of Drug-degrading Proteins by Measuring the Blood Levels of Drugs That Have Been Taken Toge
ClinicalTrials.gov study NCT00866853. IPD Sharing: Not stated. Countries: 0. Publications: 0.
the Effect of Virtual Reality Exercise on Selected Electrolytes Levels in Intradialytic Patients
ClinicalTrials.gov study NCT07316725. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Feeding Level Is Associated With Altered Liver Transcriptome and Follicle Selection in the Hen
GEO Series GSE175780. Gallus gallus. 5 samples. Type: Expression profiling by high throughput sequencing.
Increased sucrose levels mediate selective mRNA translation in Arabidopsis
GEO Series GSE59306. Arabidopsis thaliana. 24 samples. Type: Expression profiling by array.
Selected tissues of two Polish goat breeds do not differ on genomic level
GEO Series GSE89693. Capra hircus; Bos taurus. 24 samples. Type: Expression profiling by array.
Gene expression profile at single cell level of selected bone marrow from the wild type and the Txnip knock-out mice
GEO Series GSE212427. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
The levels of human PDAC microRNAs’ expression in 10 patients with longest survival and 10 with shortest survival were selected
GEO Series GSE106198. Homo sapiens. 20 samples. Type: Non-coding RNA profiling by array.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.