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ShareScore release 0.7.1
Dataset results
86 results for “optogenetic”
Mechanistic insights into cancer drug resistance through optogenetic PI3K signaling hyperactivation
GEO Series GSE212748. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.
Effect of repeated optogenetic stimulation on chromatin accessibility in the mouse dentate gyrus [ATAC-seq]
GEO Series GSE227201. Mus musculus. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Effect of repeated optogenetic stimulation on gene expression in the mouse dentate gyrus [RNA-seq]
GEO Series GSE227200. Mus musculus. 30 samples. Type: Expression profiling by high throughput sequencing.
Effect of repeated optogenetic stimulation on gene expression and chromatin accessibility in the mouse dentate gyrus
GEO Series GSE227202. Mus musculus. 42 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Optogenetic neural stem cells microarray
GEO Series GSE106515. Rattus norvegicus. 6 samples. Type: Expression profiling by array.
RAW data for Memories are not written in stone: Re-writing fear memories by means of non-invasive brain stimulation and optogenetic manipulations
<p>During fear conditioning, thalamic and cortical af- ferents convey conditioned stimulus (CS) and unconditioned stimulus (US) sensory information into the baso-lateral amyg- dala (BLA), causing a marked potentiation of excitatory syn- apses by long-term synaptic plasticity (LTP). This phenomenon causes indeed an increase of firing activity of a specific class of neurons, called “fear neurons”. Figure legend A) Fear neurons stimulate central amygdala (CeA) (serial processing) causing a strong increase of the whole amygdala output triggering both motor and auto- nomic fear behaviour by involving periaqueductal gray matter (PAG) and hypothalamus. Connection between cortical pre- limbic (PrL) and BLA neurons is able to stimulate the activity of BLA fear neurons causing a further increase in CeA activity. BLA neurons activity is also potentiated by a backward excitatory pathway originating from CeA. CS-US association induces in CeA neurons similar learning-dependent modifications occur- ring in BLA (parallel processing). From BLA, CS-US information is also redirected to Basal Ganglia which support the instru- mental response. B) During the extinction phase, the input from cortical infralimbic (IL) area suppresses the BLA fear neurons activity by the interplay with intrinsic inhibitory interneurons. Moreover, IL area directly inhibits the CeA trough activation of intercalated cells (ITCs), a scattered group of GABAergic neu- rons mainly located around the BLA area. The local inhibitory circuit further reduces the neural activity of fear neurons of BLA neurons and the subsequent BLA-CeA pathway, thereby sup- pressing the fear response.</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.