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111
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ShareScore release 0.9.0
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111 results for “parasite resistance”
Data from: Variation in costs of parasite resistance among natural host populations
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Data from: A link between heritable parasite resistance and mate choice in dung beetles
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Data from: Effects of antibiotic resistance alleles on bacterial evolutionary responses to viral parasites
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Data from: A common-garden experiment to quantify evolutionary processes in copepods: the case of emamectin benzoate resistance in the parasitic sea louse Lepeophtheirus salmonis
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Data from: Trans-generational priming of resistance in wild flour beetles reflects the primed phenotypes of laboratory populations and is inhibited by co-infection with a common parasite
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Data from: Enriched rearing environment and wild genetic background can enhance survival and disease resistance of salmonid fishes during parasite epidemics
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Variation in parasite resistance of Arctic charr, Salvelinus alpinus, between and within sympatric morphs
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Data from: Independent origins of resistance or susceptibility of parasitic wasps to a defensive symbiont
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Data from: MHC-I provides both quantitative resistance and susceptibility to blood parasites in blue tits in the wild
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Data from: Do parasites and antioxidant availability affect begging behaviour, growth rate and resistance to oxidative stress?
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Data from: Within-host competition and drug resistance in the human malaria parasite Plasmodium falciparum
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Data from: Pre-adapting parasitic phages to a pathogen leads to increased pathogen clearance and lowered resistance evolution with Pseudomonas aeruginosa cystic fibrosis bacterial isolates
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Genome-scanning of Amazonian Plasmodium falciparum shows subtelomeric instability and clindamycin resistant parasites
GEO Series GSE22861. Plasmodium falciparum. 16 samples. Type: Genome variation profiling by genome tiling array.
Piperaquine-resistant PfCRT mutations differentially impact drug transport, hemoglobin catabolism and parasite physiology in Plasmodium falciparum asexual blood stages
GEO Series GSE205515. Plasmodium falciparum. 13 samples. Type: Expression profiling by array.
Transcriptome sequencing of WT and chloroquine resistance transporter (TgCRT) ortholog-deficient Toxoplasma parasites
GEO Series GSE116539. Toxoplasma gondii. 4 samples. Type: Expression profiling by high throughput sequencing.
Piperaquine Resistance is Associated with a Copy Number Variation on Chromosome 5 in Drug-Pressured Plasmodium falciparum Parasites
GEO Series GSE27907. Plasmodium falciparum. 4 samples. Type: Genome variation profiling by genome tiling array.
Leishmania parasites exchange drug-resistance genes through extracellular vesicles
GEO Series GSE200222. Leishmania infantum. 6 samples. Type: Other.
Genetic and molecular basis of drug resistance and species-specific drug action in Schistosome parasites
GEO Series GSE51847. Schistosoma mansoni. 5 samples. Type: Expression profiling by high throughput sequencing.
Digestive exophagy of bacterial biofilms by parasitic intestinal amoeba and its impact on stress tolerance, antibiotic resistance and cytotoxicity
GEO Series GSE233645. Entamoeba histolytica. 9 samples. Type: Expression profiling by high throughput sequencing.
Data from: Adaptation to parasites and costs of parasite resistance in mutator and non-mutator bacteria
Parasitism creates selection for resistance mechanisms in host populations and is hypothesized to promote increased host evolvability. However, the influence of these traits on host evolution when parasites are no longer present is unclear. We used experimental evolution and whole-genome sequencing of Escherichia coli to determine the effects of past and present exposure to parasitic viruses (phages) on the spread of mutator alleles, resistance and bacterial competitive fitness. We found that mutator alleles spread rapidly during adaptation to any of four different phage species, and this pattern was even more pronounced with multiple phages present simultaneously. However, hypermutability did not detectably accelerate adaptation in the absence of phages and recovery of fitness costs associated with resistance. Several lineages evolved phage resistance through elevated mucoidy, and during subsequent evolution in phage-free conditions they rapidly reverted to non-mucoid, phage-susceptible phenotypes. Genome sequencing revealed that this phenotypic reversion was achieved by additional genetic changes rather than by genotypic reversion of the initial resistance mutations. Insertion sequence (IS) elements played a key role in both the acquisition of resistance and adaptation in the absence of parasites; unlike single nucleotide polymorphisms (SNPs), IS insertions were not more frequent in mutator lineages. Our results provide a genetic explanation for rapid reversion of mucoidy, a phenotype observed in other bacterial species including human pathogens. Moreover, this demonstrates that the types of genetic change underlying adaptation to fitness costs, and consequently the impact of evolvability mechanisms such as increased point-mutation rates, depend critically on the mechanism of resistance.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.