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146
datasets available to search
ShareScore release 0.9.0
Dataset results
146 results for “phase imaging”
Phase II Study of Ultra-high-dose Hypofractionated vs. Single-dose Image-Guided Radiotherapy for Prostate Cancer
ClinicalTrials.gov study NCT02570919. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Spin structure relation to phase contrast imaging of isolated magnetic Bloch and Neel skyrmions
<p>Data set associated with publication "Spin structure relation to phase contrast imaging of isolated magnetic Bloch and Neel skyrmions"</p>
Second wave, late-phase neuroinflammation in the brain of aged 5xFAD transgenic Alzheimer's disease model mice iden-tified using macrolaser light sheet microscopy imaging with tissue clearing
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Imaging and phase-locking of non-linear spin waves
<p>All primary data and simulation scripts used in the manuscript and SI</p>
MATLAB code for processing images of the in-situ etching process and analysis of etching kinetics for MAX phase to MXene transformation
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Raw diffraction images of SemiSWEET (phasing data by Se-SAD)
<p>Diffraction images of SeMet-labeled SemiSWEET from <em>Escherichia coli</em>. This phase information was used for PDB entries <a href="http://www.pdb.org/pdb/search/structidSearch.do?structureId=4X5M">4X5M</a> and <a href="http://www.pdb.org/pdb/search/structidSearch.do?structureId=4X5N">4X5N</a> (<a href="https://doi.org/10.1038/ncomms7112">Lee et al. 2015</a>). All data were collected from loop-harvested crystals on BL32XU, SPring-8 at wavelengths of 0.97920 Å (peak) or 0.98200 Å (low remote) using the MX225HS CCD detector.</p> <p>From SeMet-derivatised crystals, several helical (180-360°/crystal, 2 or 3°/frame) or non-helical datasets were collected using 15×10 or 15×1μm<sup>2</sup> beam. The crystals belonged to space group <em>P</em>2<sub>1</sub>2<sub>1</sub>2 with unit cell parameter a~54, b~101, c~59 Å.</p>
DAPI and Phase Contrast Images Dataset
<p>Data was acquired on an Olympus IX83 microscope using a 20x/0.4 Ph2 Objective.</p> <p>Kohler illimination was established before acquistion started.</p> <p>Sample consists of cultured HeLa Cells on #1.5 (170 um) coverslips, 12mm diameter.</p> <p> </p> <p>A single coverlsip was imaged in a 10x10 grid with no overlap (total: 100 images)</p> <p>Each image was acquired sequentially in</p> <ul> <li><strong>Phase Contrast</strong> (50ms exposure time, using a 535nm LED)</li> <li><strong>DAPI</strong> 100 ms exposure time</li> </ul>
Data for MS: Optimization of signal and noise in x-ray phase and dark field imaging with a wire mesh
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Dataset for Phase-Diverse Imaging and Models for Real-World Aberration Correction
<p>The work is currently submitted for publication.</p>
A Phase II Trial of 18F-AV-45 Positron Emission Tomography (PET) Imaging in Healthy Volunteers, Patients With Mild Cognitive Impairment (MCI) and Patients With Alzheimer's Disease (AD)
ClinicalTrials.gov study NCT00702143. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Phase I Study of IMRT and Molecular-Image Guided Adaptive Radiation Therapy for Advanced HNSCC
ClinicalTrials.gov study NCT01283178. IPD Sharing: NO. Countries: 1. Publications: 0.
A Phase II Trial of Florbetapir (18F) Positron Emission Tomography (PET) Imaging in Japan of Healthy Volunteers, Patients With Mild Cognitive Impairment (MCI) and Patients With Alzheimer's Disease (AD
ClinicalTrials.gov study NCT01662882. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Data from: Quantitative analysis of fundus-image sequences reveals phase of spontaneous venous pulsations
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First ISCCP Regional Experiment (FIRE) Cirrus Phase II Environmental & Technology Laboratory (ETL) Doppler Radar Images (FIRE_CI2_ETL_RADAR)
The First ISCCP Regional Experiments have been designed to improve data products and cloud/radiation parameterizations used in general circulation models (GCMs). Specifically, the goals of FIRE are (1) to seek the basic understanding of the interaction of physical processes in determining life cycles of cirrus and marine stratocumulus systems and the radiative properties of these clouds during their life cycles and (2) to investigate the interrelationships between ISCCP data, GCM parameterizations, and higher space and time resolution cloud data. To-date, four intensive field-observation periods were planned and executed: a cirrus IFO (October 13 - November 2, 1986); a marine stratocumulus IFO off the southwestern coast of California (June 29 - July 20, 1987); a second cirrus IFO in southeastern Kansas (November 13 - December 7, 1991); and a second marine stratocumulus IFO in the eastern North Atlantic Ocean (June 1 - June 28, 1992). Each mission combined coordinated satellite, airborne, and surface observations with modeling studies to investigate the cloud properties and physical processes of the cloud systems.The National Oceanic and Atmospheric Administration (NOAA) Environmental Technology Laboratory (ETL) Doppler radar was used during the Fire Cirrus II experiment in Coffeyville, Kansas to document the structural, kinematic, microphysical and turbulent properties of climatically important cirrus cloud systems. Data were collected from November 13, 1991 through November 29, 1991.
Dataset of A2780 and G361 cells - efect of FITC phototoxicity, quantitative phase imaging (2/2)
<p>Part of article Feith, M,Vičar, T., Gumulec, J., Raudenská, M. Wingren, AG, Masařík, M., Balvan, J. Quantitative Phase Dynamics of Cancer Cell Populations Affected by Blue Light, <em>Appl. Sci.</em> <strong>2020</strong>, <em>10</em></p> <p>Increased exposition to blue light may induce many changes in cell behavior and significantly affect the critical characteristics of cells. Here we show that multimodal holographic microscopy (MHM) within advanced image analysis is capable of correctly distinguishing between changes in cell motility, cell dry mass, cell density, and cell death induced by blue light. We focused on the effect of blue light with a wavelength of 485 nm on morphological and dynamical parameters of four cell lines, malignant PC-3, A2780, G361 cell lines, and the benign PNT1A cell line. We used MHM with blue light doses 24 mJ/cm<sup>2</sup>, 208 mJ/cm<sup>2 </sup>and two kinds of expositions (500 and 1000 ms) to acquire real-time quantitative phase information about cellular parameters. It has been shown that specific doses of the blue light significantly influence cell motility, cell dry mass and cell density. These changes were often specific for the malignant status of tested cells. Blue light dose 208 mJ/cm<sup>2 </sup>× 1000 ms affected malignant cell motility but did not change the motility of benign cell line PNT1A. This light dose also significantly decreased proliferation activity in all tested cell lines but was not so deleterious for benign cell line PNT1A as for malignant cells. Light dose 208 mJ/cm<sup>2 </sup>× 1000 ms oppositely affected cell mass in A2780 and PC-3 cells and induced different types of cell death in A2780 and G361 cell lines. Cells obtained the least damage on lower doses of light with shorter time of exposition.</p> <p><strong>Materials and Methods </strong></p> <p><em>Cell Lines</em></p> <p>The PC-3, A2780, PNT1A, and G361 cell lines were purchased from HPA Culture Collections (Salisbury, UK). PC-3 prostate cancer cell line was derived from bone metastasis of a 4-grade prostatic adenocarcinoma of a 62-year-old Caucasian male The A2780 cell line was derived from the ovarian carcinoma of a nontreated patient according to ECACC. PNT1A cell line was established from prostatic epithelial tissue of healthy 35-years old male and immortalized by plasmid transfection containing the SV40 genome with defective replication origin. The G361 cell line was established from a malignant melanoma of a 31-year-old male Caucasian. The G361 cells produce melanin for up to 50 population doublings. As the aim of this study is to compare the effect of blue light on the cell lines differing by morphology, transformation state, sensitivity to cell death, and origin, we decided to use the cell lines listed above. PC-3 cells are larger in comparison with small A2780 cells. Benign PNT1A cell line differs from malignant PC-3, and all four cell lines are derived from diverse tissues of origin. Furthermore, melanoma G361 cells expressing melanin may differ in the reaction of cells to blue light exposure.</p> <p></p> <p><em>Cell Cultivation</em></p> <p>All four cell lines were cultivated in 25 cm<sup>2</sup> flasks with 5 ml of media at 37 °C in a humidified incubator (60%) with 5% CO<sub>2 </sub>(Sanyo, Osaka City, Japan). Cell lines A2780, PNT1A and G361 were cultured in RPMI-1640 medium with phenol red indicator, L–glutamine, FBS and antibiotics penicillin/streptomycin (Sigma Aldrich Co., St. Louise, MO, USA). For the PC-3 cell line cultivation, Ham´s F-12 medium with FBS and antibiotics (Sigma Aldrich Co., St. Louis, MO, USA) was used. The same supplementation with antibiotics (penicillin 100 U/mL and streptomycin 0.1 mg/mL) and 10% FBS was used in both media. The cell medium was changed two times per week. Cell subculturing was done with 10% of trypsin solution (PAA, Pasching, Austria) with previous washing with EDTA (0.02% in PBS buffer).</p> <p><em>QPI and Holographic Microscopy and Fluorescence Setting</em></p> <p>QPI was performed by using a Q-PHASE multimodal holographic microscope (Telight, Brno, CZ). The Q-PHASE is equipped with fluorescence module using a halogen lamp as a non-coherent source of blue light. In this work, the module was used as a source of blue light for treatment of observed cell lines. The 485 nm light waves are emitted by the fluorescence light source of the attached module. Before the imaging experiment, cells were cultivated overnight in a concentration of 7000 cells/mL in flow chamber µ-Slide I Lauer Family (Ibidi, Martinsried, Germany). During the measurements, the chamber with cells was incubated in 37 °C humidified, 5% CO<sub>2</sub> atmosphere in H201–for Mad City Labs Z100/Z500 piezo Z-stages (Okolab, Ottaviano NA, Italy). Images and holograms were captured with lens Nikon Plan 10/0.3 and CCD camera (XIMEA MR4021 MC-VELETA, Münster, Germany) respectively. The fluorescence mode used was a plasma light source (Sutter Instrument Lambda XL Novato, CA, USA). Cells were irradiated with a 485 nm light with a 25 nm bandwidth. Light doses 0 mJ/cm<sup>2</sup>, 24 mJ/cm<sup>2</sup> and 208 mJ/cm<sup>2 </sup>were achieved by the combination of time exposition and light intensity.</p> <p>The images were acquired automatically from seven positions every 3 min for 24 h. Holographic images were collected by custom software and raw data were numerically reconstructed. The numerical reconstruction was performed by custom software where the established methods of the fast Fourier-transform and phase unwrapping are implemented. The output from the software is an unwrapped phase image. This image has high intrinsic contrast and can be processed by an available image processing software. The unwrapped phase image is integrated phase shift through the cell and it is proportional to integrated cell dry mass density.</p>
Images Dataset for the Work of Phase Separation-based Antiviral Decoy Particles as Basis for Programmable Broad-spectrum Therapeutics
<p>Images dataset for the work of Phase Separation-based Antiviral Decoy Particles as Basis for Programmable Broad-spectrum Therapeutics.</p> <p>Used for the code cited in the paper.</p>
A verified open-access AI-based chemical microparticle image database for in-situ particle visualization and quantification in multi-phase flow
<p>This report provided a new method and idea for the detection, segmentation, classification, and quantitative analysis of four dispersed phase particles - "DPPs" (agglomeration, bubble, crystal, and droplet) in chemical multi-phase flow processes.</p>
Functional Imaging in the Acute Phase of Transient Ischemic Attacks
ClinicalTrials.gov study NCT03928977. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Beta Cell Imaging During and Shortly After the Honeymoon Phase of T1D
ClinicalTrials.gov study NCT03917238. IPD Sharing: NO. Countries: 1. Publications: 0.
Phase 2b Imaging Study of RAD101 in Participants With Suspected Recurrent Brain Metastases
ClinicalTrials.gov study NCT06777433. IPD Sharing: NO. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.