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ShareScore release 0.9.0
Dataset results
95 results for “population-based study”
Population-based Registry Study on Primary Hip Fracture Surgery
ClinicalTrials.gov study NCT06773884. IPD Sharing: NO. Countries: 1. Publications: 0.
Differences in Trends Malignant Germ Cell Tumors in Males and Females: A SEER Population-based Study
ClinicalTrials.gov study NCT00322790. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The Longterm Risk of Advanced Colorectal Neoplasia After Colonoscopy - A Population-based Cohort Study in Hong Kong
ClinicalTrials.gov study NCT04815525. IPD Sharing: NO. Countries: 1. Publications: 0.
Surgery in Early Life and Child Development at School-entry: A Population-based Study
ClinicalTrials.gov study NCT02595801. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Population-based Atrial Fibrillation Screening in Individuals With NT-proBNP Above Median in the Tromsø Study
ClinicalTrials.gov study NCT07343895. IPD Sharing: NO. Countries: 1. Publications: 0.
Prevalence of Obesity Among Adult Patients With Congenital Heart Disease: a Population-based Study
ClinicalTrials.gov study NCT06661434. IPD Sharing: NO. Countries: 1. Publications: 0.
Helicobacter Pylori Infection and Gastric Diseases in Lao PDR: First Community-Wide Population-Based Study
ClinicalTrials.gov study NCT07340593. IPD Sharing: NO. Countries: 1. Publications: 0.
Data from: Association between probable postnatal depression and increased infant mortality and morbidity: findings from the DON population-based cohort study in rural Ghana
Open the record for dataset details and reuse information.
Data from: Ectopic fat obesity presents the greatest risk for incident type 2 diabetes: a population-based longitudinal study
Open the record for dataset details and reuse information.
Effect of Weekend Admission on Mortality Associated With Severe Acute Kidney Injury in England: a Propensity Score Matched, Population-based Study
ClinicalTrials.gov study NCT02947698. IPD Sharing: NO. Countries: 0. Publications: 0.
The Association Between Food Insecurity and Incident Type 2 Diabetes in Canada: A Population-based Cohort Study
ClinicalTrials.gov study NCT03243136. IPD Sharing: NO. Countries: 0. Publications: 0.
Dataset related to the article "Relation between anticholinergic burden and cognitive impairment: Results from the Monzino 80-plus population-based study"
<p><em>The file contains raw data related to the article "Relation between anticholinergic burden and cognitive impairment: Results from the Monzino 80-plus population-based study", available from <a href="https://onlinelibrary.wiley.com/doi/10.1002/pds.5159">https://onlinelibrary.wiley.com/doi/10.1002/pds.5159</a>.</em></p> <p> </p> <p><strong>Abstract of the manuscript:</strong></p> <p><strong>Purpose: </strong>We examined data collected in the Monzino 80-plus study to assess the relations between cognitive performance and ACB scores according to the hypothesis that a higher anticholinergic burden is associated with reduced cognitive performance.</p> <p><strong>Methods: </strong>The Monzino 80-plus is an ongoing, prospective, door-to-door population-based study started in 2002 among all residents 80 years or older in eight municipalities of Varese province, Italy. To establish the relation between cognitive impairment and the anticholinergic drug burden we recorded the ACB score for each patient at baseline. The relations between ACB score and dementia or MMSE scores were also examined after exclusion of patients taking any antipsychotic.</p> <p><strong>Results: </strong>A sample of 2140 elderly people was eligible for analysis. A significant dose-effect relationship was observed between total ACB score and diagnosis of dementia in univariate and multivariate models. Patients in ACB class ≥4 had about 4.5 times the risk of diagnosis of dementia. A relation was also found between higher ACB scores and lower MMSE scores; patients who scored 4 or more had a mean of 6.4 points lower than those not taking anticholinergic drugs. The dose-effect relationship between ACB score and diagnosis of dementia was not maintained after exclusion of patients using antipsychotics, while the association between higher ACB scores and lower MMSE scores was still present, with patients in ACB class ≥4 having a mean score about 4.4 lower.</p> <p><strong>Conclusions: </strong>There are clear relations between anticholinergic load and reduced cognitive performance, while the association with dementia remains uncertain. For primary care and geriatric clinicians, an ACB score ≥ 4 can be considered the cut-off to identify high-risk populations who may benefit from the evaluation of anticholinergic burden with the ACB scale.</p>
Dataset related to article: The role of diet on the risk of dementia in the oldest old: The Monzino 80-plus population-based study
<p>Pseudonimized single subject data relative to the results reported in the article, in .xlsx format</p>
Direct Costs of Care for Adults with Soft Tissue Sarcomas: A Population-Based Study
<p>The clinical treatment of soft tissue sarcoma (STS) has evolved substantially over the last decade. This population-based cohort study based on real-world data included all incidental STS recorded by the Veneto Cancer Registry in 2017. Data on hospital admissions, emergency department and outpatient visits, drug prescriptions, and use of medical devices within two years from STS diagnosis were obtained from administrative databases. The average per-patient real-world costs over this two-year period, in total and by single expenditure item, were calculated and stratified by stage of disease at diagnosis, tumor histology and tumor site. The mean total cost per patient amounted to EUR 16,793. A higher TNM stage at diagnosis was associated with higher healthcare costs, as follows: compared with stage I, the average total cost per patient was 1.32, 2.18 and 3.36 times greater for stages II, III and IV, respectively. Hospital stays generated the greatest costs (averaging EUR 7950 per patient), followed by outpatient visits (mean EUR 3947 per patient) and drug prescriptions (mean EUR 3664 per patient). Given the paucity of population-based studies, the present results can serve as a reference for further cost-effectiveness analyses on care strategies for patients with STS.</p>
Impact of Wide Local Excision on Melanoma Patient Survival: A Population-Based Study
<p>Promoting standardization and quality assurance (QA) in oncology on the strength of real-world data is essential to ensure better patient outcomes. Wide excision after primary tumor biopsy is a fundamental step in the therapeutic pathway for cutaneous malignant melanoma (CMM). The aim of this population-based cohort study is to assess adherence to wide local excision in a cohort of patients diagnosed with CMM and the impact of this recommended procedure on overall and disease-specific survival.This retrospective cohort study concerns CMM patients diagnosed in the Veneto region (north-east Italy) in 2017, included in the high-resolution Veneto Cancer Registry, and followed up through linkage with the regional mortality registry up until February 29th, 2020. Using population-level real-world data, linking patient-level cancer registry data with administrative records of clinical procedures may shed light on the real-world treatment of CMM patients in accordance with current guidelines. After excluding TNM stage IV patients, a Cox regression analysis was performed to test whether the completion of a wide local excision was associated with a difference in melanoma-specific and overall survival, after adjusting for other covariates. No wide excision after the initial biopsy was performed in 9.7% of cases in our cohort of 1,305 patients. After adjusting for other clinical prognostic characteristics, Cox regression revealed that failure to perform a wide local excision raised the hazard ratio of death in terms of overall survival (HR = 4.80, 95% CI: 2.05-11.22, <em>p</em> < 0.001) and melanoma-specific survival (HR = 2.84, 95% CI: 1.04-7.76, <em>p</em> = 0.042). By combining clinical and administrative data, this study on real-world clinical practice showed that almost one in ten CMM patients did not undergo wide local excision surgery. Monitoring how diagnostic-therapeutic protocols are actually implemented in the real world may contribute significantly to promoting quality improvements in the management of oncological patients.</p>
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Allen Brain Atlas
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International Brain Laboratory public data
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OpenNeuro
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