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290 results for “thyroid hormones”
Data from: Heritable variation in maternally-derived yolk androgens, thyroid hormones and immune factors
Maternal reproductive investment can critically influence offspring phenotype, and thus these maternal effects are expected to be under strong natural selection. Knowledge on the extent of heritable variation in the physiological mechanisms underlying maternal effects is however limited. In birds, resource allocation to eggs is a key mechanism for mothers to affect their offspring and different components of the egg may or may not be independently adjusted. We studied the heritability of egg components and their genetic and phenotypic covariation in great tits (Parus major), using captive-bred full siblings of wild origin. Egg mass, testosterone (T) and androstenedione (A4) hormone concentrations showed moderate heritability, in agreement with earlier findings. Interestingly, yolk triiodothyronine hormone (T3), but not its precursor, thyroxine hormone (T4), concentration was heritable. An immune factor, albumen lysozyme, showed moderate heritability, but yolk immunoglobulins (IgY) did not. The genetic correlation estimates were moderate but statistically nonsignificant; a trend for a positive genetic correlation was found between A4 and egg mass, T and lysozyme and IgY and lysozyme, respectively. Interestingly, phenotypic correlations were found only between A4 and T, and T4 and T3, respectively. Given that these egg components are associated with fitness-related traits in the offspring (and mother), and that we show that some components are heritable, it opens the possibility that natural selection may shape the rate and direction of phenotypic change via egg composition.
Data from: Are thyroid hormones mediators of incubation temperature-induced phenotypes in birds?
Incubation temperature influences a suite of traits in avian offspring. However, the mechanisms underlying expression of these phenotypes are unknown. Given the importance of thyroid hormones in orchestrating developmental processes, we hypothesized that they may act as an upstream mechanism mediating the effects of temperature on hatchling phenotypic traits such as reduced growth and thermoregulation. We found that plasma T3, but not T4 concentrations, differed among newly-hatched wood ducks (Aix sponsa) from different embryonic incubation temperatures. T4 at hatching correlated with time spent hatching, and T3 correlated with hatchling body condition, tarsus length, time spent hatching, and incubation period. In addition, the T3:T4 ratio differed among incubation temperatures up at hatch. Our findings are consistent with the hypothesis that incubation temperature modulates plasma thyroid hormones which in turn influences multiple aspects of duckling phenotype.
thyroid hormone pathway and circadian clock genes
<p>thyroid hormone pathway and circadian clock genes</p>
The Relation Between Thyroid , Parathyroid Hormones and eGFR in CKD Patients in Assiut
ClinicalTrials.gov study NCT05243979. IPD Sharing: Not stated. Countries: 0. Publications: 8.
Thyroid and Cortisol Hormone Response to Sepsis
ClinicalTrials.gov study NCT06289179. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Correlation Between TCM Syndrome Factors and TSH Changes of Thyroid Hormone Withdrawal Before Iodine Therapy in Postoperative Patients With Thyroid Cancer
ClinicalTrials.gov study NCT04916262. IPD Sharing: Not stated. Countries: 0. Publications: 4.
Effects of Thyroid Hormone Enzyme Blocking on Hypothyroidism
ClinicalTrials.gov study NCT01801033. IPD Sharing: Not stated. Countries: 0. Publications: 3.
Thyroid and Adrenocortical Hormone Replacement in Organ Donors
ClinicalTrials.gov study NCT04528797. IPD Sharing: NO. Countries: 0. Publications: 1.
Temporal pole responds to subtle changes in local thyroid hormone signaling
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Data from: Experimental manipulation of food availability leads to short-term intra-clutch adjustment in egg mass but not in yolk androgen or thyroid hormones
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Data from: Are thyroid hormones mediators of incubation temperature-induced phenotypes in birds?
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Data from: Thyroid hormone modulates offspring sex ratio in a turtle with temperature-dependent sex determination
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Data from: Heritable variation in maternally-derived yolk androgens, thyroid hormones and immune factors
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A coregulator shift, rather than the canonical switch, underlies thyroid hormone action in liver
GEO Series GSE159648. Mus musculus. 53 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
DNA methylation dynamics in primary human monocytes exposed to thyroid hormone ex vivo
GEO Series GSE180692. Homo sapiens. 15 samples. Type: Methylation profiling by genome tiling array.
Knockout of thyroid hormone receptor alpha a (thraa) enhances cardiac regeneration in zebrafish through metabolic and hypoxic regulation
GEO Series GSE282482. Danio rerio. 28 samples. Type: Expression profiling by high throughput sequencing.
Thyroid Hormone (TH) Controls The Remodeling Of The Pancreas And The Liver, Part A
GEO Series GSE16074. Xenopus laevis. 16 samples. Type: Expression profiling by array.
FOXO1 regulates a subset of thyroid hormone target genes
GEO Series GSE68803. Mus musculus. 9 samples. Type: Expression profiling by array.
Single-cell RNA based phenotyping reveals a pivotal role of thyroid hormone receptor alpha for hypothalamic development
GEO Series GSE212068. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Glis3 regulates the expression of thyroid hormone synthetic genes in coordination with other thyroid transcription factors
GEO Series GSE207777. Rattus norvegicus; Mus musculus. 21 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
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Allen Brain Atlas
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Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
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The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
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