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2,143
datasets available to search
ShareScore release 0.9.0
Dataset results
2,143 results for “All Spinal Cord”
Bulk RNA-sequencing of spinocerebellar tract neuron populations in cervical and thoracic sections of mouse spinal cord
GEO Series GSE129948. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Multiomics profiling of molecular and cellular dynamics of spinal cord injury in a rat [miRNA-seq]
GEO Series GSE295917. Rattus norvegicus. 43 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Transcriptomic analysis of spinal cord microglial cells from NTg and ATXN2-Q33;TDP-43 adult mice
GEO Series GSE224581. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
MicroRNA expression profiling in a mouse spinal cord injury model [P15 and P90, 12h and 3d]
GEO Series GSE89517. Mus musculus. 24 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Transcriptional study of the temporal evolution after severe traumatic spinal cord injury (SCI) and neural progenitor cells (NPCs)-transplantation intervention.
GEO Series GSE183591. Rattus norvegicus. 28 samples. Type: Expression profiling by array.
Neural ensembles that encode nocifensive mechanical and heat pain in mouse spinal cord
GEO Series GSE253533. Mus musculus. 28 samples. Type: Expression profiling by high throughput sequencing.
Sex- and region-specific transcriptomic differences in brainstem and cervical spinal cord microglia in rat offspring exposed to gestational intermittent hypoxia
GEO Series GSE142478. Rattus norvegicus. 40 samples. Type: Expression profiling by high throughput sequencing.
Next Generation Sequencing of zebrafish spinal cord transcriptomes before and after injury
GEO Series GSE182868. Danio rerio. 49 samples. Type: Expression profiling by high throughput sequencing.
Single-cell transcriptomic data in the spinal cord of Taiwanese type I SMA mice
GEO Series GSE208629. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
Rescue of spinal cord pathology by peripherally administered AR-targeted ASO in symptomatic AR113Q mice
GEO Series GSE300077. Mus musculus. 11 samples. Type: Expression profiling by high throughput sequencing.
Rosette-forming glioneuronal tumour arising in the spinal cord: a case report and molecular profiling
GEO Series GSE64891. Homo sapiens. 1 samples. Type: Genome variation profiling by array.
Decoding the m6A expression profiling of spinal cord after spared nerve injury at three time points with RIP-Seq
GEO Series GSE202166. Mus musculus. 24 samples. Type: Methylation profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Next Generation Sequencing of zebrafish intraspinal serotonergic neurons in the injury segment and distal segments after spinal cord injury
GEO Series GSE182869. Danio rerio. 11 samples. Type: Expression profiling by high throughput sequencing.
Changing expression profiles of circular RNA reveal the key regulators and interaction networks of competing endogenous RNA in neurogenic bladder after suprasacral spinal cord injured
GEO Series GSE227447. Rattus norvegicus. 12 samples. Type: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing.
Single cell sequencing of WT and hb-egfaKO zebrafish spinal cord, at 1 week after sham or transection injury.
GEO Series GSE213435. Danio rerio. 4 samples. Type: Expression profiling by high throughput sequencing.
Effect of IP6K2-deletion on mRNA expression in mouse spinal cord and duodenum
GEO Series GSE189239. Mus musculus. 4 samples. Type: Expression profiling by array.
Gene expression microarray analysis of whole mouse hamstring muscles to identify genes promoting the devlopment of neurogenic heterotopic ossifications following spinal cord injury
GEO Series GSE165062. Mus musculus. 16 samples. Type: Expression profiling by array.
Data from: Sleep disordered breathing is associated with brain vascular reactivity in spinal cord injury
Objective: Our goal was to determine the population-level odds of individuals with SCI experiencing fatigue and sleep apnea, to elucidate relationships with level and severity of injury, and to examine associations with abnormal cerebrovascular responsiveness. Methods: We used population-level data, meta-analyses, and primary physiological assessments to provide a large-scale integrated assessment of sleep-related complications after SCI. Population-level and meta-analyses included more than 60,000 able-bodied individuals and more than 1,800 individuals with SCI. Physiological assessments were completed on a homogenous sample of individuals with cervical SCI, and matched controls. We examined the prevalence of 1) self-reported chronic fatigue, 2) clinically-identified sleep apnea, and 3) cerebrovascular responsiveness to changing CO2. Results: Logistic regression revealed a 7-fold elevated odds of chronic fatigue after SCI [OR: 7.9, 95% CI: 3.5-16.2], and that fatigue and trouble sleeping are correlated with the level and severity of injury. We further show that those with SCI experience elevated risk of clinically-defined sleep-disordered breathing in more than 600 individuals with SCI [pooled OR: 3.1, 95% CI: 1.3-7.5]. We confirmed that individuals with SCI experience a high rate of clinically-defined sleep-apnea using primary polysomnography assessments. We then provide evidence using syndromic analysis that sleep-disordered breathing is a factor strongly associated with impaired cerebrovascular responsiveness to CO2 in patients with SCI. Conclusions: Individuals with SCI have an increased prevalence of sleep-disordered breathing, which may partially underpin their increased risk of stroke. There is thus a need to integrate sleep-related breathing examinations into routine care for individuals with SCI.
Acute and chronic effects of motorised dental burr assisted thoracic spinal laminectomy on the functionality and welfare of the contusion spinal cord injury rat model
<p><span>This study focused on acute and chronic effects of the recently established Dental Burr Assisted (DBA) technique to perform laminectomy at T10-T11 vertebral level in a rat model of spinal cord injury (SCI)on animal welfare as well as functionality, and compared it to the conventional technique. The utility as a model of chronic pain, and the effects of SCI on memory was also assessed, using DBA technique and was compared to conventional technique of laminectomy. A total of 24 Crl:WI female rats were assigned randomly to four equal groups- conventionally laminectomised, dental burr assisted laminectomised, conventionally laminectomised with spinal cord contusion and dental burr assisted laminectomised with spinal cord contusion injuries. In a 56 day long study, the animals were tested for bleeding during surgery; Basso Beattie and Bresnahan (BBB) score; body weight changes; Rat Grimace Scale (RGS); light phase open field activity; dark phase home cage activity; sucrose preference as an indicator for hedonistic behaviour; novel object recognition to assess short and long term memory during acute and chronic stages; mechanical allodynia using von Frey filaments; and detailed histopathology of the spinal cord to estimate surviving neuronal number and area of vacuoles at the end of the study. The results indicate that the analgesia provided during post-operative phase did not affect the outcome of the chronic pain model and that, DBA technique can be a functional alternative to the conventional technique to achieve better welfare without affecting the functionality and research outcome in SCI injury studies. </span></p> <p> </p>
Data from: Ergogenic effects of an epidural neuroprosthesis in one individual with spinal cord injury
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.