Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
1,274
datasets available to search
ShareScore release 0.9.0
Dataset results
1,274 results for “Disease Model”
Insights for disease modeling from single cell transcriptomics of iPSC-derived neurons and astrocytes across differentiation time and co-culture
GEO Series GSE260498. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer’s disease model
GEO Series GSE134151. Mus musculus. 48 samples. Type: Expression profiling by high throughput sequencing.
Wilson disease: intersecting DNA methylation and histone acetylation mechanisms affect gene expression regulation in a mouse model of hepatic copper accumulation [ChIP-Seq]
GEO Series GSE168971. Mus musculus. 70 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Longitudinal modeling of human neuronal aging reveals the contribution of the RCAN1-TFEB pathway to Huntington's disease neurodegeneration
GEO Series GSE241430. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
An epoxide hydrolase inhibitor reduces neuroinflammation in a mouse model of Alzheimer’s disease
GEO Series GSE161848. Mus musculus. 12 samples. Type: Expression profiling by array.
Co-culture model of B-cell acute lymphoblastic leukemia recapitulates a transcription signature of chemotherapy-refractory minimal residual disease
GEO Series GSE148520. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
Expression data of hypothalamus from the BACHD and HTT overexpression mouse models of Huntington's disease (HD)
GEO Series GSE215217. Mus musculus. 38 samples. Type: Expression profiling by array.
Effect of paraquat and nicotine on gene expression in a Drosophila melanogaster Parkinson's disease model
GEO Series GSE35930. Drosophila melanogaster. 11 samples. Type: Expression profiling by array.
Cell-intrinsic glial pathology is conserved across human and murine models of Huntington Disease
GEO Series GSE154141. Homo sapiens; Mus musculus. 129 samples. Type: Expression profiling by array.
System-wide identification of myeloid markers of TB disease and HIV-induced reactivation in the macaque model of Mtb infection and Mtb/SIV co-infection
GEO Series GSE213850. Macaca mulatta; Homo sapiens. 15 samples. Type: Expression profiling by array.
Transcriptome profiling in knock-in mouse models of Huntington's disease (liver_mRNA).
GEO Series GSE78273. Mus musculus. 93 samples. Type: Expression profiling by high throughput sequencing.
DNA methylation profiles across different brain regions in Alzheimer disease mice models
GEO Series GSE47036. Mus musculus. 16 samples. Type: Methylation profiling by genome tiling array.
Neurodegeneration and Neuroinflammation are Linked, but Independent of α-Synuclein Inclusions, in a Seeding/Spreading Mouse Model of Parkinson’s Disease
GEO Series GSE155716. Mus musculus. 42 samples. Type: Expression profiling by array.
Specific changes of liver transcriptome in the early stages of copper accumulation in the mouse model of wilson disease
GEO Series GSE5348. Mus musculus. 6 samples. Type: Expression profiling by array.
Effect of BDNF on the APP transgenic mouse model of Alzheimer's disease
GEO Series GSE14499. Mus musculus. 26 samples. Type: Expression profiling by array.
REST and Neural Gene Network Dysregulation in iPS Cell Models of Alzheimer’s Disease (Affymetrix neurons data set)
GEO Series GSE117585. Homo sapiens. 11 samples. Type: Expression profiling by array.
Long-term Urolithin A treatment ameliorates disease pathology in Alzheimer's Disease mouse models [MET_DC]
GEO Series GSE214416. Mus musculus. 23 samples. Type: Expression profiling by array.
Inhaled Xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy [Xenon in IFNgr1 cKO]
GEO Series GSE271471. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
PIKFYVE Inhibition Mitigates Disease in Models of Diverse Forms of ALS [1]
GEO Series GSE221015. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
The disease modeling of Jacob Syndrome reveals an aberrant genome-wide expression modulation from the Y chromosome [RRBS]
GEO Series GSE264396. Homo sapiens. 31 samples. Type: Methylation profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.