Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
989
datasets available to search
ShareScore release 0.9.0
Dataset results
989 results for “myelodysplastic syndrome”
Gene expression profiles of CD34+ cells from patients with myelodysplastic syndrome CAA or AML
GEO Series GSE107968. Homo sapiens. 9 samples. Type: Expression profiling by array.
Myelodysplastic syndrome marrow stroma shows widespread aberrant hypermethylation that is abrogated by treatment with DNMT inhibitors
GEO Series GSE60233. Homo sapiens. 9 samples. Type: Methylation profiling by genome tiling array.
Modeling myelodysplastic syndromes in mice by altered Hoxa1 spliceform expression (CMP)
GEO Series GSE227775. Mus musculus. 11 samples. Type: Expression profiling by array.
Myelodysplastic Syndromes IWG
International Working Group (IWG) for the prognosis of Myelodysplastic Syndromes. Derivation of the Molecular International Prognosis Scoring System for MDS. Comprehensive profiling of 3,323 treatment-naive MDS samples. Data generated by the Papaemmanuil Lab 2022. The cases here are only those under the age of 40 years old.
Germline Genetics of Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML)
Myelodysplastic syndromes (MDS) are part of a heterogeneous and overlapping group of clonal diseases that arise in the hematopoietic stem or progenitor cells and also include acute myeloid leukemia (AML), myeloproliferative neoplasms (MPN), and the hybrid MDS/MPN entities. Individuals with MDS have a high risk of progressing to leukemia, with approximately 30% expected to develop AML. This study evaluates genetic susceptibility to myeloid malignancy using data from population-based case control studies of myelodysplastic syndromes and acute myeloid leukemia in adults (ages 18-85 years) and pediatric MDS cases with banked samples at the Center for International Blood and Marrow Transplant Research (CIBMTR). Adult cases were identified through the Minnesota Cancer Reporting System and controls were recruited from the State Driver's License/Identification Card list. DNA samples were collected via mouthwash collection kits (AML cases and controls) or Oragene saliva collection kits (adult MDS cases and controls). Pediatric MDS samples were banked at CIBMTR prior to receipt of a transplant and DNA was extracted from isolated T cells or whole blood samples. Genotyping data were generated using the Illumina Global Diversity array and quality control and genotype calling was conducted using established best practices. Our primary analyses investigated the contribution of genetic variation to MDS risk and evaluated the role of the killer cell immunoglobulin receptors (KIR) on incidence and survival.
Modeling myelodysplastic syndromes in mice by altered Hoxa1 spliceform expression
GEO Series GSE62853. Mus musculus. 11 samples. Type: Expression profiling by array.
Real-time quantitative PCR analysis of autophagy and apoptosis in Myelodysplastic syndromes (MDS)
GEO Series GSE204797. Homo sapiens. 13 samples. Type: Expression profiling by RT-PCR.
Affymetrix SNP6.0 microarray data - Myelodysplastic syndromes
GEO Series GSE23300. Homo sapiens. 91 samples. Type: Genome variation profiling by SNP array; SNP genotyping by SNP array.
Non-erythroid heme biosynthesis gene, ALAS1, up-regulation after hypomethylating agents predict better outcome in patients with myelodysplastic syndrome
<p>Supplementary Figure: mRNA next generation sequence analysis. (A) mRNA expression of MDS patients treated with AZA. MDS001: MDS with early AZA treatment failure. MDS001_1: before AZA treatment; MDS001_2: under AZA treatment, with response; MDS001_3: AZA treatment failure with leukemia change. MDS002: AZA failure within 2 years. MDS002_1: before treatment; MDS002_2: under AZA treatment, with response. MDS003: long-term AZA treatment response; MDS001: MDS001-1+MDS001-2+MDS001-3. MDS002: MDS002-1 + MDS002-2. MDS003 is MDS003-1</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.