Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
1,249
datasets available to search
ShareScore release 0.9.0
Dataset results
1,249 results for “R data”
Data set from Flocco SF, Dellafiore F, Caruso R, Giamberti A, Micheletti A, Negura DG, Piazza L, Carminati M, Chessa M. Improving health perception through a transition care model for adolescents with congenital heart disease. J Cardiovasc Med (Hagerstown). 2019 Apr;20(4):253-260. doi: 10.2459/JCM.0000000000000770. PMID: 30676496.
<p>Data set from Flocco SF, Dellafiore F, Caruso R, Giamberti A, Micheletti A, Negura DG, Piazza L, Carminati M, Chessa M. Improving health perception through a transition care model for adolescents with congenital heart disease. J Cardiovasc Med (Hagerstown). 2019 Apr;20(4):253-260. doi: 10.2459/JCM.0000000000000770. PMID: 30676496.</p> <p> </p> <p>this is the abstract:</p> <p><strong>Aims: </strong>The aim of this study was to assess the impact of a transition clinic model on adolescent congenital heart disease (CHD) patients' health perception outcomes. The transition clinic model consists of multidisciplinary standardized interventions to educate and support CHD patients and represents a key element in the adequate delivery of care to these individuals during their transition from childhood to adulthood. Currently, empirical data regarding the impact of transition clinic models on the improvement of health perceptions in CHD adolescent patients are lacking.</p> <p><strong>Methods: </strong>A quasi-experimental design was employed. Quality of life, satisfaction, health perceptions and knowledge were assessed at the time of enrolment (T0) and a year after enrolment (T1), respectively. During the follow-up period, the patients enrolled (aged 11-18 years) were involved in the CHD-specific transition clinic model (CHD-TC).</p> <p><strong>Results: </strong>A sample of 224 CHD adolescents was enrolled (60.7% boys; mean age: 14.84 ± 1.78 years). According to Warnes' classification, 22% of patients had simple heart defect, 56% showed moderate complexity and 22% demonstrated severe complexity. The overall results suggested a good impact of the CHD-TC on adolescents' outcomes, detailing in T1 the occurrence of a reduction of pain (P < 0.001) and anxiety (P < 0.001) and an improvement of knowledge (P < 0.001), life satisfaction (P < 0.001), perception of health status (P < 0.001) and quality of life (P < 0.001).</p> <p><strong>Conclusion: </strong>The CHD-TC seems to provide high-quality care to the patient by way of a multidisciplinary team. The results of the present study are encouraging and confirm the need to create multidisciplinary standardized interventions in order to educate and support the delivery of care for CHD adolescents and their families.</p>
Data set from Gorla R, De Marco F, Morganti S, Finotello A, Brambilla N, Testa L, Agnifili ML, Tusa M, Auricchio F, Bedogni F. Transcatheter aortic valve implantation with the Portico and Evolut R bioprostheses in patients with elliptic aortic annulus. EuroIntervention. 2020 Apr 3;15(18):e1588-e1591. doi: 10.4244/EIJ-D-19-00115. PMID: 31186219.
<p>Data set from Gorla R, De Marco F, Morganti S, Finotello A, Brambilla N, Testa L, Agnifili ML, Tusa M, Auricchio F, Bedogni F. Transcatheter aortic valve implantation with the Portico and Evolut R bioprostheses in patients with elliptic aortic annulus. EuroIntervention. 2020 Apr 3;15(18):e1588-e1591. doi: 10.4244/EIJ-D-19-00115. PMID: 31186219.</p> <p> </p><p> </p> <p></p>
Data set from Barbic F, Minonzio M, Cairo B, Shiffer D, Dipasquale A, Cerina L, Vatteroni A, Urechie V, Verzeletti P, Badilini F, Vaglio M, Iatrino R, Porta A, Santambrogio M, Gatti R, Furlan R. Effects of different classroom temperatures on cardiac autonomic control and cognitive performances in undergraduate students. Physiol Meas. 2019 Jun 4;40(5):054005. doi: 10.1088/1361-6579/ab1816. PMID: 30970334.
<p>Data set from Barbic F, Minonzio M, Cairo B, Shiffer D, Dipasquale A, Cerina L, Vatteroni A, Urechie V, Verzeletti P, Badilini F, Vaglio M, Iatrino R, Porta A, Santambrogio M, Gatti R, Furlan R. Effects of different classroom temperatures on cardiac autonomic control and cognitive performances in undergraduate students. Physiol Meas. 2019 Jun 4;40(5):054005. doi: 10.1088/1361-6579/ab1816. PMID: 30970334.</p> <p> </p> <p>This is the abstract:</p> <p><strong>Objective: </strong> Indoor microclimate may affect students' wellbeing, cardiac autonomic control and cognitive performance with potential impact on learning capabilities. To assess the effects of classroom temperature variations on the autonomic profile and students' cognitive capabilities.</p> <p><strong>Approach: </strong> Twenty students attending Humanitas University School, (14M, age 21 ± 3 years) underwent a single-lead ECG continuous recording by a portable device during a 2 h lecture when classroom temperature was set 'neutral' (20 °C-22 °C, Day 1) and when classroom temperature was set to 24 °C-26 °C (Day 2). ECGs were sent by telemetry to a server for off-line analysis. Spectral analysis of RR variability provided indices of cardiac sympathetic (LF<sub>nu</sub>), vagal (HF, HF<sub>nu</sub>) and cardiac sympatho-vagal modulation (LF/HF). Symbolic analysis of RR variability provided the percentage of sequences of three heart periods with no significant change in RR interval (0V%) and with two significant variations (2V%) reflecting cardiac sympathetic and vagal modulation, respectively. Students' cognitive performance (memory, verbal comprehension and reasoning) was assessed at the end of each lecture using the Cambridge Brain Sciences cognitive evaluation tool.</p> <p><strong>Main results: </strong> Classroom temperature and CO<sub>2</sub> were assessed every 5 min. Classroom temperatures were 22.4 °C ± 0.1 °C (Day 1) and 26.2 °C ± 0.1 °C (Day 2). Student's thermal comfort was lower during Day 2 compared to Day 1. HR, LF/HF and 0V% were greater during Day 2 (79.5 ± 12.1 bpm, 6.9 ± 7.1 and 32.8% ± 10.3%) than during Day 1 (72.6 ± 10.8 bpm, 3.4 ± 3.7, 21.4% ± 9.2%). Conversely, 2V% was lower during Day 2 (23.1% ± 8.1%) than during Day 1 (32.3% ± 11.4%). Short-term memory, verbal ability and the overall cognitive C-score scores were lower during Day 2 (10.3 ± 0.3; 8.1 ± 1.2 and 10.9 ± 2.0) compared to Day 1 (11.7 ± 2.1; 10.7 ± 1.7 and 12.6 ± 1.8).</p> <p><strong>Significance: </strong> During Day 2, a shift of the cardiac autonomic control towards a sympathetic predominance was observed compared to Day 1, in the presence of greater thermal discomfort. Furthermore, during Day 2 reduced cognitive performances were found.</p>
Data set from Dalla Vecchia LA, Barbic F, De Maria B, Cozzolino D, Gatti R, Dipaola F, Brunetta E, Zamuner AR, Porta A, Furlan R. Can strenuous exercise harm the heart? Insights from a study of cardiovascular neural regulation in amateur triathletes. PLoS One. 2019 May 7;14(5):e0216567. doi: 10.1371/journal.pone.0216567. PMID: 31063482; PMCID: PMC6504093.
<p>Data set from Dalla Vecchia LA, Barbic F, De Maria B, Cozzolino D, Gatti R, Dipaola F, Brunetta E, Zamuner AR, Porta A, Furlan R. Can strenuous exercise harm the heart? Insights from a study of cardiovascular neural regulation in amateur triathletes. PLoS One. 2019 May 7;14(5):e0216567. doi: 10.1371/journal.pone.0216567. PMID: 31063482; PMCID: PMC6504093</p> <p> </p> <p>This is the abstract:</p> <p>Regular exercise is recommended to improve the cardiovascular risk profile. However, there is growing evidence that extreme volumes and intensity of long-term exertion may increase the risk of acute cardiac events. The aim of this study is to investigate the after-effects of regular, strenuous physical training on the cardiovascular neural regulation in a group of amateur triathletes compared to age-matched sedentary controls. We enrolled 11 non-elite triathletes (4 women, age 24±4 years), who had refrained from exercise for 72 hours, and 11 age-matched healthy non-athletes (3 women, age 25±2 years). Comprehensive echocardiographic and cardiopulmonary exercise tests were performed at baseline. Electrocardiogram, non-invasive blood pressure, respiratory activity, and muscle sympathetic nerve activity (MSNA) were continuously recorded in a supine position (REST) and during an incremental 15° step-wise head-up tilt test up to 75° (TILT). Blood samples were collected for determination of stress mediators. Autoregressive spectral analysis provided the indices of the cardiac sympathetic (LFRR) and vagal (HFRR) activity, the vascular sympathetic control (LFSAP), and the cardiac sympatho-vagal modulation (LF/HF). Compared to controls, triathletes were characterized by greater LFRR, LF/HF ratio, LFSAP, MSNA, and lower HFRR at REST and during TILT, i.e. greater overall cardiovascular sympathetic modulation together with lower cardiac vagal activity. Cortisol and adrenocorticotropic hormone concentrations were also higher in triathletes. In conclusion, triathletes were characterized by signs of sustained cardiovascular sympathetic overactivity. This might represent a risk factor for future cardiovascular events, given the known association between chronic excessive sympathetic activity and increased cardiovascular risk.</p>
Data Set from Renna LV, Bosè F, Brigonzi E, Fossati B, Meola G, Cardani R. Aberrant insulin receptor expression is associated with insulin resistance and skeletal muscle atrophy in myotonic dystrophies. PLoS One. 2019 Mar 22;14(3):e0214254. doi: 10.1371/journal.pone.0214254. PMID: 30901379; PMCID: PMC6430513.
<p>Data Set from Renna LV, Bosè F, Brigonzi E, Fossati B, Meola G, Cardani R. Aberrant insulin receptor expression is associated with insulin resistance and skeletal muscle atrophy in myotonic dystrophies. PLoS One. 2019 Mar 22;14(3):e0214254. doi: 10.1371/journal.pone.0214254. PMID: 30901379; PMCID: PMC6430513.</p> <p> </p> <p>This is the abstact:</p> <p>Myotonic dystrophy type 1 (DM1) and type 2 (DM2) are autosomal dominant multisystemic disorders linked to two different genetic loci and characterized by several features including myotonia, muscle atrophy and insulin resistance. The aberrant alternative splicing of insulin receptor (IR) gene and post-receptor signalling abnormalities have been associated with insulin resistance, however the precise molecular defects that cause metabolic dysfunctions are still unknown. Thus, the aims of this study were to investigate in DM skeletal muscle biopsies if beyond INSR missplicing, altered IR protein expression could play a role in insulin resistance and to verify if the lack of insulin pathway activation could contribute to skeletal muscle wasting. Our analysis showed that DM skeletal muscle exhibits a lower expression of the insulin receptor in type 1 fibers which can contribute to the defective activation of the insulin pathway. Moreover, the aberrant insulin signalling activation leads to a lower activation of mTOR and to an increase in MuRF1 and Atrogin-1/MAFbx expression, possible explaining DM skeletal muscle fiber atrophy. Taken together our data indicate that the defective insulin signalling activation can contribute to skeletal muscle features in DM patients and are probably linked to an aberrant specific-fiber type expression of the insulin receptor.</p>
Data set from Bosè F, Renna LV, Fossati B, Arpa G, Labate V, Milani V, Botta A, Micaglio E, Meola G, Cardani R. TNNT2 Missplicing in Skeletal Muscle as a Cardiac Biomarker in Myotonic Dystrophy Type 1 but Not in Myotonic Dystrophy Type 2. Front Neurol. 2019 Sep 27;10:992. doi: 10.3389/fneur.2019.00992. PMID: 31611837; PMCID: PMC6776629.
<p>Data set from Bosè F, Renna LV, Fossati B, Arpa G, Labate V, Milani V, Botta A, Micaglio E, Meola G, Cardani R. TNNT2 Missplicing in Skeletal Muscle as a Cardiac Biomarker in Myotonic Dystrophy Type 1 but Not in Myotonic Dystrophy Type 2. Front Neurol. 2019 Sep 27;10:992. doi: 10.3389/fneur.2019.00992. PMID: 31611837; PMCID: PMC6776629.</p> <p> </p> <p>This is the abstract:</p> <p> </p> <p>Cardiac involvement is one of the most important manifestations of the multisystemic phenotype of patients affected by myotonic dystrophy (DM) and represents the second cause of premature death. Molecular mechanisms responsible for DM cardiac defects are still unclear; however, missplicing of the cardiac isoform of troponin T (<em>TNNT2</em>) and of the cardiac sodium channel (<em>SCN5A</em>) genes might contribute to the reduced myocardial function and conduction abnormalities seen in DM patients. Since, in DM skeletal muscle, the <em>TNNT2</em> gene shows the same aberrant splicing pattern observed in cardiac muscle, the principal aim of this work was to verify if the <em>TNNT2</em> aberrant fetal isoform expression could be secondary to myopathic changes or could reflect the DM cardiac phenotype. Analysis of alternative splicing of <em>TNNT2</em> and of several genes involved in DM pathology has been performed on muscle biopsies from patients affected by DM type 1 (DM1) or type 2 (DM2) with or without cardiac involvement. Our analysis shows that missplicing of muscle-specific genes is higher in DM1 and DM2 than in regenerating control muscles, indicating that these missplicing could be effectively important in DM skeletal muscle pathology. When considering the <em>TNNT2</em> gene, missplicing appears to be more evident in DM1 than in DM2 muscles since, in DM2, the <em>TNNT2</em> fetal isoform appears to be less expressed than the adult isoform. This evidence does not seem to be related to less severe muscle histopathological alterations that appear to be similar in DM1 and DM2 muscles. These results seem to indicate that the more severe <em>TNNT2</em> missplicing observed in DM1 could not be related only to myopathic changes but could reflect the more severe general phenotype compared to DM2, including cardiac problems that appear to be more severe and frequent in DM1 than in DM2 patients. Moreover, <em>TNNT2</em> missplicing significantly correlates with the QRS cardiac parameter in DM1 but not in DM2 patients, indicating that this splicing event has good potential to function as a biomarker of DM1 severity and it should be considered in pharmacological clinical trials to monitor the possible effects of different therapeutic approaches on skeletal muscle tissues.</p> <p><strong>Keywords: </strong> alternative splicing; cardiac involvement; cardiac troponin T; myotonic dystrophies; skeletal muscle.</p>
Data set fromMazzaccaro D, Miri R, Derbel B, Modafferi A, Nano G. Hypogastric artery coverage during endovascular aneurysm repair in octogenarian and younger patients. J Cardiovasc Med (Hagerstown). 2019 Aug;20(8):557-563. doi: 10.2459/JCM.0000000000000799. PMID: 30950984.
<p>Data set fromMazzaccaro D, Miri R, Derbel B, Modafferi A, Nano G. Hypogastric artery coverage during endovascular aneurysm repair in octogenarian and younger patients. J Cardiovasc Med (Hagerstown). 2019 Aug;20(8):557-563. doi: 10.2459/JCM.0000000000000799. PMID: 30950984.</p> <p> </p> <p>This is the abstract:</p> <p><strong>Aim: </strong> To report our experience about hypogastric artery coverage during endovascular aneurysm repair (EVAR) for aortoiliac aneurysms in patients younger than 80 years (group A) compared with octogenarian patients (group B).</p> <p><strong>Methods: </strong> Data of consecutive EVAR with hypogastric artery coverage from 01/1998 to 12/2016 were retrospectively analyzed. Primary outcomes were the occurrence of ischemic colitis, type II endoleak and buttock claudication both at 30 days and in the long term. P values less than 0.05 were considered statistically significant.</p> <p><strong>Results: </strong> The hypogastric artery was covered in 107 patients. Twenty-three (21.5%) were octogenarian (group B). At 30 days, one type II endoleak occurred in group B, whereas 16 patients of group A experienced buttock claudication. There were no cases of ischemic colitis. During follow-up (median 63.5 months), no cases of ischemic colitis occurred. Six new type II endoleaks were recorded (five in group B and one in group A, P = 0.0001). Buttock claudication persisted in four patients of group A. No new cases of buttock claudication were observed.</p> <p><strong>Conclusion: </strong> Unilateral hypogastric artery coverage during EVAR for aortoiliac aneurysms can be performed with an acceptable rate of postoperative complication. Postoperative buttock claudication was more frequent in younger patients, whereas a type II endoleak occurred mostly in octogenarian patients during follow-up.</p>
QCA-2024-SCC-SU25530 R&D data
Project Code: QCA-2024-SCC-SU25530.This project is classified as CONFIDENTIAL. All information, data, and results associated with this project are strictly restricted to authorized personnel only. Any dissemination, distribution, or copying of the project details is strictly prohibited without prior approval from the project lead and the university's Office of Research Compliance.
QCA-2024-SCC-KE23187 R&D data
Project Code: QCA-2024-SCC-KE23187.This project is classified as CONFIDENTIAL. All information, data, and results associated with this project are strictly restricted to authorized personnel only. Any dissemination, distribution, or copying of the project details is strictly prohibited without prior approval from the project lead and the university's Office of Research Compliance.
QCA-2024-SCC-VH24614 R&D data
Project Code: QCA-2024-SCC-VH24614.This project is classified as CONFIDENTIAL. All information, data, and results associated with this project are strictly restricted to authorized personnel only. Any dissemination, distribution, or copying of the project details is strictly prohibited without prior approval from the project lead and the university's Office of Research Compliance.
QCA-2024-SCC-RX21950 R&D data
Project Code: QCA-2024-SCC-RX21950.This project is classified as CONFIDENTIAL. All information, data, and results associated with this project are strictly restricted to authorized personnel only. Any dissemination, distribution, or copying of the project details is strictly prohibited without prior approval from the project lead and the university's Office of Research Compliance.
QCA-2024-SCC-CD78114 R&D data
Project Code: QCA-2024-SCC-CD78114.This project is classified as CONFIDENTIAL. All information, data, and results associated with this project are strictly restricted to authorized personnel only. Any dissemination, distribution, or copying of the project details is strictly prohibited without prior approval from the project lead and the university's Office of Research Compliance.
QCA-2024-SCC-JR44097 R&D data
Project Code: QCA-2024-SCC-JR44097.This project is classified as CONFIDENTIAL. All information, data, and results associated with this project are strictly restricted to authorized personnel only. Any dissemination, distribution, or copying of the project details is strictly prohibited without prior approval from the project lead and the university's Office of Research Compliance.
QCA-2024-SCC-GQ29860 R&D data
Project Code: QCA-2024-SCC-GQ29860.This project is classified as CONFIDENTIAL. All information, data, and results associated with this project are strictly restricted to authorized personnel only. Any dissemination, distribution, or copying of the project details is strictly prohibited without prior approval from the project lead and the university's Office of Research Compliance.
QCA-2024-SCC-QN78209 R&D data
Project Code: QCA-2024-SCC-QN78209.This project is classified as CONFIDENTIAL. All information, data, and results associated with this project are strictly restricted to authorized personnel only. Any dissemination, distribution, or copying of the project details is strictly prohibited without prior approval from the project lead and the university's Office of Research Compliance.
Data and R code for "Network analysis of workshop activities reveals increasing transdisciplinarity of German biodiversity research community"
<p>This is the dataset and all files needed to re-run the R analysis in " Network analysis of workshop activities reveals increasing transdisciplinarity of German biodiversity research community ".</p>
QCA-2024-SCC-FJ03428 R&D data
Project Code: QCA-2024-SCC-FJ03428.This project is classified as CONFIDENTIAL. All information, data, and results associated with this project are strictly restricted to authorized personnel only. Any dissemination, distribution, or copying of the project details is strictly prohibited without prior approval from the project lead and the university's Office of Research Compliance.
QCA-2024-SCC-FE55363 R&D data
Project Code: QCA-2024-SCC-FE55363.This project is classified as CONFIDENTIAL. All information, data, and results associated with this project are strictly restricted to authorized personnel only. Any dissemination, distribution, or copying of the project details is strictly prohibited without prior approval from the project lead and the university's Office of Research Compliance.
QCA-2024-SCC-GX86713 R&D data
Project Code: QCA-2024-SCC-GX86713.This project is classified as CONFIDENTIAL. All information, data, and results associated with this project are strictly restricted to authorized personnel only. Any dissemination, distribution, or copying of the project details is strictly prohibited without prior approval from the project lead and the university's Office of Research Compliance.
QCA-2024-SCC-EW88499 R&D data
Project Code: QCA-2024-SCC-EW88499.This project is classified as CONFIDENTIAL. All information, data, and results associated with this project are strictly restricted to authorized personnel only. Any dissemination, distribution, or copying of the project details is strictly prohibited without prior approval from the project lead and the university's Office of Research Compliance.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.