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Dataset results
1,921 results for “onset”
Systemic approaches reveal anti-adipogenic signals at the onset of obesity–related inflammation in white adipose tissue
GEO Series GSE132885. Mus musculus. 168 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Multi-omics co-localization with genome-wide association studies reveals a context-specific genetic mechanism at a childhood onset asthma risk locus [RNA-Seq]
GEO Series GSE172367. Homo sapiens. 190 samples. Type: Expression profiling by high throughput sequencing.
Single cell RNA-seq reveals expansion of IGRP-reactive CD4+ T cells in recent onset type I diabetes (single-cell RNA-seq of CD8+ influenza-reactive T cells)
GEO Series GSE96564. Homo sapiens. 45 samples. Type: Expression profiling by high throughput sequencing.
Interaction with WDR5 recruits MYC to a small cohort of genes required for tumor onset and maintenance
GEO Series GSE126207. Homo sapiens. 42 samples. Type: Expression profiling by high throughput sequencing; Other.
Single-cell transcriptome analysis reveals atypical monocytes circulating ahead of acute graft-versus-host disease clinical onset
GEO Series GSE269338. Homo sapiens. 14 samples. Type: Expression profiling by high throughput sequencing.
Developmental Dynamics of Kranz Cell Transcriptional Specificity in Maize Leaf Reveals Early Onset of C4-related Processes
GEO Series GSE54272. Zea mays. 12 samples. Type: Expression profiling by high throughput sequencing.
Genetic architecture differences between pediatric and adult-onset inflammatory bowel diseases in the Polish population
GEO Series GSE79094. Homo sapiens. 108 samples. Type: Genome variation profiling by SNP array.
TEFM variants impair mitochondrial transcription elongation causing childhood-onset neurological disease
GEO Series GSE185245. Homo sapiens. 35 samples. Type: Expression profiling by high throughput sequencing.
Single cell RNA-seq reveals expansion of IGRP-reactive CD4+ T cells in recent onset type I diabetes (single-cell RNA-seq of T-cell clone)
GEO Series GSE96562. Homo sapiens. 149 samples. Type: Expression profiling by high throughput sequencing.
Transcriptional profiling in adult onset ADPKD mouse model based on Pkd2 inactivation
GEO Series GSE149739. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Liver Chromatin accessibility landscapes during onset of salmon maturation
GEO Series GSE156998. Salmo salar. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
FGF7 as an essential mediator for the onset of ankylosing arthropathy related to psoriatic skin lesions
GEO Series GSE234831. Mus musculus. 6 samples. Type: Expression profiling by array.
Dysregulated Placental Micrornas In Early And Late Onset Preeclampsia
GEO Series GSE103542. Homo sapiens. 24 samples. Type: Non-coding RNA profiling by array.
A Short Peptide Protects from Age-Onset Proteotoxicity
GEO Series GSE230640. Caenorhabditis elegans. 12 samples. Type: Expression profiling by high throughput sequencing.
Brain injury accelerates the onset of a reversible age-related microglial phenotype associated with hyperphagocytosis and inflammatory neurodegeneration
GEO Series GSE206618. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing.
Placental transcriptome profiles in late-onset preeclampsia: a cross-sectional observational analysis stratified by fetal sex
GEO Series GSE306864. Homo sapiens. 58 samples. Type: Expression profiling by high throughput sequencing.
Early-onset sporadic rectal cancer : Wnt- vs. Wnt+ rectal tumor
GEO Series GSE79330. Homo sapiens. 93 samples. Type: Expression profiling by array; Genome variation profiling by array.
Data from: Nonlinear dynamics forecasting of obstructive sleep apnea onsets
Recent advances in sensor technologies and predictive analytics are fueling the growth in point-of-care (POC) therapies for obstructive sleep apnea (OSA) and other sleep disorders. The effectiveness of POC therapies can be enhanced by providing personalized and real-time prediction of OSA episode onsets. Previous attempts at OSA prediction are limited to capturing the nonlinear, nonstationary dynamics of the underlying physiological processes. This paper reports an investigation into heart rate dynamics aiming to predict in real time the onsets of OSA episode before the clinical symptoms appear. A prognosis method based on a nonparametric statistical Dirichlet-Process Mixture-Gaussian-Process (DPMG) model to estimate the transition from normal states to an anomalous (apnea) state is utilized to estimate the remaining time until the onset of an impending OSA episode. The approach was tested using three datasets including (1) 20 records from 14 OSA subjects in benchmark ECG apnea databases (Physionet.org), (2) records of 10 OSA patients from the University of Dublin OSA database and (3) records of eight subjects from previous work. Validation tests suggest that the model can be used to track the time until the onset of an OSA episode with the likelihood of correctly predicting apnea onset in 1 min to 5 mins ahead is 83.6 ± 9.3%, 80 ± 8.1%, 76.2 ± 13.3%, 66.9 ± 15.4%, and 61.1 ± 16.7%, respectively. The present prognosis approach can be integrated with wearable devices, enhancing proactive treatment of OSA and real-time wearable sensor-based of sleep disorders.
Data from: Sporadic late-onset nemaline myopathy: clinical spectrum, survival and treatment outcomes
OBJECTIVES: To describe the clinical phenotype, long-term treatment outcome and overall survival of sporadic late onset nemaline myopathy (SLONM) with or without a monoclonal protein (MP). METHODS: we conducted a retrospective chart review of patients seen between September 2000 and June 2017 and collected clinical, laboratory and survival data. Treatment response was classified as mild, moderate, or marked as adjudged by predefined criteria. RESULTS: We identified 28 patients with SLONM, 17 (61%) had an associated MP. Median age at symptom onset was 62 years. Diagnosis was often delayed by a median of 35 months from symptom onset. There was no difference in clinical or laboratory features between patients with or without MP. Although the majority of patients had proximal or axial weakness at onset, about 18% of patients had atypical presentations. 7/9 (78%) patients receiving intravenous immunoglobulin (IVIG), 6/8 (75%) receiving hematologic therapy as either autologous stem cell transplant (ASCT), or chemotherapy and 1/8 (13%) receiving immunosuppressive therapies responded to treatment (p=0.001). All 3 patients with marked response were treated with IVIG, 2 of them had a MP. The 5-year and 10-year overall survivals from symptom onset were 92% and 68% respectively, with no difference between patients with or without MP. CONCLUSIONS: SLONM has a wide spectrum of clinical presentations. In this contemporary case series, overall survival of patients did not seem to be affected by the presence of a MP. Initial treatment with IVIG is reasonable in all patients, followed by ASCT or chemotherapy as second-line therapy in patients with an associated MP.
Genetic Heterogeneity of Early-Onset Colorectal Cancer in Asian Populations: A Comprehensive Systematic Review
<p>Genetic Heterogeneity of Early-Onset Colorectal Cancer in Asian Populations: A Comprehensive Systematic Review</p>
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.