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1,274 results for “Disease Model”

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geo20/100

Therapeutic JAK1 inhibition reverses lupus nephritis in a mouse model and demonstrates transcriptional changes consistent with human disease

GEO Series GSE277400. Mus musculus. 48 samples. Type: Expression profiling by array.

openGEO-OpenSep 2025View details →
geo20/100

Investigation of de novo mutations in a schizophrenia case-parent trio by induced pluripotent stem cell based in vitro disease-modelling: Convergence of schizophrenia and autism-related cellular pheno

GEO Series GSE145656. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2020View details →
geo20/100

Cortical transcriptional changes in a chemically-induced neuronopathic Gaucher disease mouse model

GEO Series GSE78757. Mus musculus. 24 samples. Type: Expression profiling by array.

openGEO-OpenAug 2016View details →
geo20/100

Effects of BDNF in Rodent Models of Aging and Alzheimer's Disease

GEO Series GSE14522. Mus musculus; Rattus norvegicus. 53 samples. Type: Expression profiling by array.

openGEO-OpenJan 2009View details →
geo20/100

Next generation sequencing based transcriptome comparison between wild-type Drosophila and an Alzheimer's disease model

GEO Series GSE109489. Drosophila melanogaster. 24 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJun 2020View details →
geo20/100

Selective targeting and modulation of plaque associated microglia via systemic hydroxyl dendrimer administration in an Alzheimer’s disease mouse model​.

GEO Series GSE266470. Mus musculus. 32 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMay 2024View details →
geo20/100

Effects of RG2833 (HDAC1/3 Inhibitor) on the gene expression of Male and Female TgF344 Alzheimer’s disease Rat model.

GEO Series GSE247142. Rattus norvegicus. 20 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2024View details →
geo20/100

Salivary gland during development and onset of xerostomia in murine model of Sjögren's syndrome-like disease

GEO Series GSE15640. Mus musculus. 25 samples. Type: Expression profiling by array.

openGEO-OpenApr 2009View details →
geo20/100

Aberrant neurodevelopment in human iPS cell-derived models of Alexander disease.

GEO Series GSE261158. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenApr 2024View details →
geo20/100

Inhaled Xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy [5xFAD-MITRG Astrocytes 6M]

GEO Series GSE271423. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2025View details →
geo20/100

Transcriptome profiling in knock-in mouse models of Huntington's disease [Liver_miRNA]

GEO Series GSE78792. Mus musculus. 96 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMar 2016View details →
geo20/100

Expression Profiling of Fibroblasts in Chronic and Acute Disease Models

GEO Series GSE121190. Mus musculus. 15 samples. Type: Expression profiling by array.

openGEO-OpenOct 2018View details →
geo20/100

Disease modeling of pulmonary fibrosis using human iPS cell-derived alveolar organoids

GEO Series GSE172123. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2021View details →
geo20/100

A novel Menin-MLL inhibitor induces specific chromatin changes and eradicates disease in models of MLL-rearranged leukemia [RNA-Seq II]

GEO Series GSE137813. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2019View details →
geo20/100

A high-fat diet exacerbates the Alzheimer's disease pathology in the hippocampus of the App[NL-F/NL-F] knock-in mouse model

GEO Series GSE152539. Mus musculus. 12 samples. Type: Expression profiling by array.

openGEO-OpenJun 2021View details →
geo20/100

Expression data from the neuron model of Alzheimer's disease (AD)

GEO Series GSE80244. Homo sapiens. 6 samples. Type: Expression profiling by array.

openGEO-OpenDec 2016View details →
geo20/100

Pharmacologic Inhibition of Epidermal Growth Factor Receptor Suppresses Non-alcoholic Fatty Liver Disease in Murine Fast-food Diet Model

GEO Series GSE130528. Mus musculus. 6 samples. Type: Expression profiling by array.

openGEO-OpenMay 2020View details →
geo20/100

Developing a novel human adult kidney organoid model to recapitulate injury-associated regeneration and polycystic kidney disease [RNA-Seq]

GEO Series GSE228971. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2023View details →
geo20/100

Insights into RNA‐mediated pathology in new mouse models of Huntington's disease

GEO Series GSE269068. Mus musculus. 12 samples. Type: Expression profiling by array.

openGEO-OpenJun 2024View details →
geo20/100

Type I Interferon Signaling Mediates Microglial Dysfunction and Senescence in Human-Mouse Chimeric Brain Models of Down Syndrome and Alzheimer’s Disease

GEO Series GSE189227. Mus musculus; Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJul 2022View details →

ScienceDex guides

Understand access before you commit

These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

Compare curated datasets

Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record