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1,154
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Dataset results
1,154 results for “Pooling”
Rat mammary expression in individuals and pools
GEO Series GSE2331. Rattus norvegicus. 56 samples. Type: Expression profiling by array.
Inner ear expression data from pooled inner ear tissue from stages 56,57,58 Xenopus laevis larval inner ears
GEO Series GSE73829. Xenopus laevis. 3 samples. Type: Expression profiling by array.
Acetyl-CoA is a Key Molecule for Nephron Progenitor Cell Pool Maintenance
GEO Series GSE210937. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Regulation of the RNAPII Pool Is Integral to the DNA Damage Response [RNA-seq]
GEO Series GSE143537. Homo sapiens. 30 samples. Type: Expression profiling by high throughput sequencing.
Fig 9 in Discovery of a rich gene pool of bat SARSrelated coronaviruses provides new insights into the origin of SARS coronavirus
Fig 9. Functional characterization of diverse ORF8 and ORF8a proteins of bat SARSr-CoVs. (A) The ORF8 proteins of SARS-CoV and bat SARSr-CoVs induces the ATF6-dependent transcriptional activity. HeLa cells were transiently transfected with the pcAGGS expression plasmids of the ORF8 of SARS-CoV GZ02, bat SARSr-CoV Rf1, WIV1 and Rf4092 and the reporter plasmid 5îATF6-GL3 for 40h. Control cells were co-transfected with the reporter plasmid and the empty pCAGGS vector for 24h, and treated with or without TM (2g/ml) for an additional 16h. The cell lysates were harvested for dual luciferase assay and data are shown as the average values from triplicate wells. (B) The ORF8a proteins of SARS-CoV and bat SARSr- CoV triggered apoptosis. 293T cells were transfected with the expression plasmids of the ORF8a of SARS-CoV Tor2 and bat SARSr-CoV Rs4084 and a pcAGGS vector control for 24h. Apoptosis was analyzed by flow cytometry after annexin V staining and the percentage of apoptotic cells were calculated. Data are shown as the average values from triplicate cells. Error bars indicate SDs. * P 0.05. https://doi.org/10.1371/journal.ppat.1006698.g009
Fig 7 in Discovery of a rich gene pool of bat SARSrelated coronaviruses provides new insights into the origin of SARS coronavirus
Fig 7. Infection of Vero E6 cells by bat SARSr-CoV WIV1, Rs4874, WIV1-Rs4231S and WIV1-Rs7327S. (A) The successful infection was confirmed by immunofluorescent antibody staining using rabbit antibody against the SARSr-CoV Rp3 nucleocapsid protein. The columns (from left to right) show staining of nuclei (blue), virus replication (red), and both nuclei and virus replication (merged double-stain images). (B) The growth curves in Vero E6 cells with a MOI of 1.0 and 0.01. https://doi.org/10.1371/journal.ppat.1006698.g007
Fig 1 in Discovery of a rich gene pool of bat SARSrelated coronaviruses provides new insights into the origin of SARS coronavirus
Fig 1. Similarity plot based on the full-length genome sequence of civet SARS CoV SZ3. Full-length genome sequences of all SARSr-CoV detected in bats from the cave investigated in this study were used as reference sequences. The analysis was performed with the Kimura model, a window size of 1500 base pairs and a step size of 150 base pairs. https://doi.org/10.1371/journal.ppat.1006698.g001
Fig 6 in Discovery of a rich gene pool of bat SARSrelated coronaviruses provides new insights into the origin of SARS coronavirus
Fig 6. Phylogenetic trees based on nucleotide sequences of ORF1a (A) and ORF1b (B). The trees were constructed by the maximum likelihood method using the LG model with bootstrap values determined by 1000 replicates. Only bootstraps! 50% are shown. The scale bars represent 0.03 (A) and 0.02 (B) substitutions per nucleotide position. Rs, Rhinolophus sinicus; Rf, Rhinolophus ferremequinum; Rm, Rhinolophus macrotis; Ra, Rhinolophus affinis; Rp, Rhinolophus pusillus; As, Aselliscus stoliczkanus; Cp, Chaerephon plicata. SARSr-CoVs detected in bats from the single cave surveyed in this study are in bold. Sequences detected in southwestern China are indicated in red. https://doi.org/10.1371/journal.ppat.1006698.g006
Fig 8 in Discovery of a rich gene pool of bat SARSrelated coronaviruses provides new insights into the origin of SARS coronavirus
Fig 8. Analysis of receptor usage by immunofluorescence assay (A) and real-time PCR (B). Virus infectivity of Rs4874, WIV1-Rs4231S and WIV1-Rs7327S was determined in HeLa cells with and without the expression of human ACE2. ACE2 expression was detected with goat anti-human ACE2 antibody followed by fluorescein isothiocyanate (FITC)-conjugated donkey anti-goat IgG. Virus replication was detected with rabbit antibody against the SARSr-CoV Rp3 nucleocapsid protein followed by cyanine 3 (Cy3)-conjugated mouse anti-rabbit IgG. Nuclei were stained with DAPI (49,6-diamidino-2-phenylindole).The columns (from left to right) show staining of nuclei (blue), ACE2 expression (green), virus replication (red) and the merged triplestained images, respectively. https://doi.org/10.1371/journal.ppat.1006698.g008
Fig 4 in Discovery of a rich gene pool of bat SARSrelated coronaviruses provides new insights into the origin of SARS coronavirus
Fig 4. Alignment of nucleotide sequences of ORF8 or ORF8a/8b. The start codons and stop codons of ORF8, 8a and 8b are marked with black boxes and the forward and reverse arrows, respectively. The deletion responsible for the split ORF8a and 8b in human SARS-CoV BJ01, Tor2 and bat SARSr-CoV Rs4084 is marked with red boxes. See the legend for Fig 3 for the origin of various sequences used in this alignment.
Fig 2 in Discovery of a rich gene pool of bat SARSrelated coronaviruses provides new insights into the origin of SARS coronavirus
Fig 2. Schematic diagram illustrating the genomic regions or ORFs with most variation between different SARS-CoV and SARSr-CoV isolates. Coding regions of the N-terminal domain (NTD) and receptor-binding domain (RBD) of the spike protein, ORF3a/b and ORF8 (8a/b) in bat SARSr-CoV genomes highly similar to those in SARS CoV genome are indicated with black boxes or arrows while the hollow boxes or arrows represent corresponding regions with less sequence similarity to those of SARS-CoV. The deletions in the RBD of some SARSr-CoVs are indicated by two vertical lines. https://doi.org/10.1371/journal.ppat.1006698.g002
Calculation template for the unit-scale framework for designing step-pool sequences
<p>This is the calculation template for the manuscript titled "A unit-scale framework for designing step-pool sequences" by Chendi Zhang, Marwan A. Hassan, Matteo Saletti, André E. Zimmermann, Mengzhen Xu and Zhaoyin Wang. The design method described in the manuscript is specifically for river restoration using artificial step-pool sequence (Zhang et al., 2018, 2020; Zimmermann et al., 2020). Version 1.0 of the calculation template was applied to a total of 21 artificial step-pools built in the Maso di Spinelle River in Italy (Lenzi 2002; Lenzi and Comiti 2003; Comiti et al. 2009). A natural step-pool sequence including 20 units in the Erlenback in Switzerland (Golly et al., 2019) was used in the Version 2.0 of the template. The instructions are included in the file. With changes in the inputs, this template can also be used for other cases where design for artificial step-pools is needed. The flow competence estimation method (Richardson and Carling, 2021) has been incorporated in the Version 2.1.</p>
Pool in the stream
<u>Source</u>: Flickr <br><u>4DCity URL</u>: <a href="https://4dcity.org/imgupload/1677514556.491.jpg">https://4dcity.org/imgupload/1677514556.491.jpg</a> <br><u>Original Image URL</u>: <a href="https://live.staticflickr.com/7810/46593743175_124d920c11_m.jpg">https://live.staticflickr.com/7810/46593743175_124d920c11_m.jpg</a>
Meta-Analysis Plan for Pooled Data for Studies VRX-RET-E22-303 and VRX-RET-E22-304
ClinicalTrials.gov study NCT01457989. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Validity of Mediastinal Blood Pool SUV Ratio
ClinicalTrials.gov study NCT05258045. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Effectiveness of Belimumab Treatment in a Subpopulation of Systemic Lupus Erythematosus (SLE) Patients: a Pooled Analysis of BLISS-52 and BLISS-76
ClinicalTrials.gov study NCT01914770. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Treatment of Systemic Lupus Erythematosus With Pooled Allogenic Mesenchymal Stem Cells
ClinicalTrials.gov study NCT04184258. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Changes in total RNA in BK deficient mice after 4h sleep deprivation [pools]
GEO Series GSE132075. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Inner ear expression data from pooled inner ear tissue from stages 50,51,52 Xenopus laevis larval inner ears
GEO Series GSE73828. Xenopus laevis. 3 samples. Type: Expression profiling by array.
Negative Elongation Factor (NELF) regulates muscle progenitor expansion for efficient myofiber repair and stem cell pool repopulation [S5_RNApolII_Cut&Tag]
GEO Series GSE162778. Mus musculus. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.