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Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
1,274
datasets available to search
ShareScore release 0.9.0
Dataset results
1,274 results for “Disease Model”
An emergent disease-associated motor neuron state precedes cell death in a mouse model of ALS [scRNA-Seq]
GEO Series GSE306676. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
Vascular oxidative stress causes neutrophil arrest in brain capillaries, leading to decreased cerebral blood flow and contributing to memory impairment in a mouse model of Alzheimer’s disease
GEO Series GSE224394. Mus musculus. 17 samples. Type: Expression profiling by high throughput sequencing.
Distinct transcriptomic and epigenomic responses of mature oligodendrocytes during disease progression in a mouse model of multiple sclerosis
GEO Series GSE250589. Mus musculus. 56 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Bombali virus infection of cynomolgus macaques as a survival model of Ebola virus disease
GEO Series GSE290671. Macaca fascicularis. 36 samples. Type: Expression profiling by high throughput sequencing.
MCM8 mediated mitophagy protects vascular health in response to nitric oxide signaling in a mouse model of Kawasaki disease
GEO Series GSE235994. Mus musculus. 19 samples. Type: Expression profiling by high throughput sequencing.
CSF1R inhibitor-mediated microglial depletion prevents reductions in striatal volume, extracellular matrix alterations, and perineuronal net loss in a mouse model of Huntington’s disease
GEO Series GSE136158. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Gut microbiome generated Phenylacetylglutamine from dietary phenylalanine is associated with Crohn's Disease and exacerbates colitis in mouse model possibly via platelet activation
GEO Series GSE204719. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Beyond single-strain models: Genetic background modifies disease presentations and molecular signatures in muscular dystrophy
GEO Series GSE316106. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
Targeting CD38 immunometabolic checkpoint improves metabolic fitness and cognition in a mouse model of Alzheimer’s disease.
GEO Series GSE290076. Mus musculus. 7 samples. Type: Expression profiling by high throughput sequencing.
Modeling endogenous HTT/mHTT pathogenesis in fibroblasts and striatal GABAergic neurons from a Mongolian family with Huntington’s disease
GEO Series GSE184255. Homo sapiens. 13 samples. Type: Expression profiling by high throughput sequencing.
An emergent disease-associated motor neuron state precedes cell death in a mouse model of ALS [multiome]
GEO Series GSE306675. Mus musculus. 10 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Anxiety-like behavior and altered hippocampal activity in a transgenic mouse model of Fabry disease
GEO Series GSE254835. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
9-cis-retinoic acid improves disease modelling in iPSC-derived liver organoids
GEO Series GSE292959. Homo sapiens. 33 samples. Type: Expression profiling by high throughput sequencing.
Pyrazole-derived TRPC3 antagonist ameliorates synaptic dysfunctions and memory deficits in Alzheimer’s disease models
GEO Series GSE253510. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Single-nucleus RNA sequencing of the hippocampal formation from a genetically diverse Alzheimer's disease mouse model (AD-BXDs)
GEO Series GSE221959. Mus musculus. 53 samples. Type: Expression profiling by high throughput sequencing.
IFNG production by self-reactive CD4 T cells drives the adrenal autoimmune pathology in the mouse model of Addison’s disease
GEO Series GSE303645. Mus musculus. 3 samples. Type: Other; Expression profiling by high throughput sequencing.
Chronic Kidney Disease in a Murine Model of non-Alcoholic Steatohepatitis (NASH)
GEO Series GSE184256. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Human lung organoid for modeling infection and disease conditions (Lung I)
GEO Series GSE157055. Homo sapiens. 7 samples. Type: Expression profiling by high throughput sequencing.
The transcriptome signature of the mouse brain after bulbectomy suggests a new model of Alzheimer’s disease with elements of major depression.
GEO Series GSE249297. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
Multicellular liver organoid model for recapitulating hepatitis C virus infection and non-alcoholic fatty liver disease progression [scRNA-Seq]
GEO Series GSE229608. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.