Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
2,073
datasets available to search
ShareScore release 0.9.0
Dataset results
2,073 results for “Comparative effectiveness”
Comparative effect of DON and plant or microbial biotransformation of DON on gene expression of piglets jejunal explants
GEO Series GSE66918. Sus scrofa; Sus scrofa domesticus. 20 samples. Type: Expression profiling by array.
Comparing Neoantigen Cancer Vaccines and Immune Checkpoint Therapy Unveils an Effective Vaccine and Anti-TREM2 Macrophage-Targeting Dual Therapy [neoAgSpCD8Tcells]
GEO Series GSE276904. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Comparative transcriptome analysis of wild and lab populations of Astyanax mexicanus uncovers differential effects of environment and morphotype on gene expression
GEO Series GSE139490. Astyanax mexicanus. 12 samples. Type: Expression profiling by high throughput sequencing.
Next generation sequencing comparing effects of FFSS, FAK inhibitor and FAK gene deletion. [FFSS]
GEO Series GSE144265. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Comparing effects of perfusion and hydrostatic pressure on human chondrocytes using gene profiles
GEO Series GSE69206. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Comparing Neoantigen Cancer Vaccines and Immune Checkpoint Therapy Unveils an Effective Vaccine and Anti-TREM2 Macrophage-Targeting Dual Therapy [CD45]
GEO Series GSE276902. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Comparative dose-response analysis of liver and kidney transcriptomic effects of trichloroethylene and tetrachloroethylene in B6C3F1 mouse
GEO Series GSE100296. Mus musculus. 58 samples. Type: Expression profiling by high throughput sequencing.
Single-cell gene expression profiles associated with myxoid liposarcoma scaffold culture compared to xenograft and effect of fusion oncogene FUS-DDIT3
GEO Series GSE191132. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Comparative and integrated functional genomics analysis of Klinefelter and Turner syndromes reveals network-wide effects of the sex chromosome dosage changes
GEO Series GSE126712. Homo sapiens. 70 samples. Type: Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing; Other.
scRNAseq analysis comparing primary CD4+ T cells in resting memory state or stimulated with anti-CD3/anti-CD28 states and the effect of loss of ADAP1
GEO Series GSE169339. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Effect on small molecule RBPJ inhibitor (RIN1) on gene expression in Jurkat cells compared to gamma secretase inhibition and siRNA knockdown of RBPJ
GEO Series GSE134401. Homo sapiens. 14 samples. Type: Expression profiling by high throughput sequencing.
Next generation sequencing comparing effects of vehicle, PTH, and YKL-05-093 in Ocy454 cells
GEO Series GSE76932. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Effect of overexpession of Stonewall (Stwl) on gene expression in germline stem cell (GSC)-like cells compared to the control
GEO Series GSE268943. Drosophila melanogaster. 8 samples. Type: Expression profiling by high throughput sequencing.
Comparing transcriptomic points of departure to apical effect concentrations for larval fathead minnow exposed to chemicals with four different modes of action
GEO Series GSE252223. Pimephales promelas. 932 samples. Type: Expression profiling by high throughput sequencing.
Characterization of EndoC-BH5 a novel human pancreatic beta cell line. Comparative expression profile with EndoC-BH1 and effect of stimulation with Interferon gamma and interleukin 1b.
GEO Series GSE224660. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.
A comparative study of the effect of Electroconvulsive therapy and Transcranial direct current stimulation in the treatment of persons suffering from treatment-resistant depression
<p>This study sought to compare the effectiveness of electroconvulsive therapy and transcranial direct current stimulation in the treament of Treatment-resistant depression.</p>
Obtained data from research comparing the effectiveness of extrinsic methods of motivation on video games
Open the record for dataset details and reuse information.
[DATABASE] Comparing the Effectiveness, Tolerability, and Acceptability of Heated Tobacco Products and Refillable Electronic Cigarettes for Cigarette Substitution (CEASEFIRE): Randomized Controlled Trial
<p><strong>Background: </strong>People who smoke and who face challenges trying to quit or wish to continue to smoke may benefit by switching from traditional cigarettes to noncombustible nicotine delivery alternatives, such as heated tobacco products (HTPs) and electronic cigarettes (ECs). HTPs and ECs are being increasingly used to quit smoking, but there are limited data about their effectiveness.</p> <p><strong>Objective: </strong>We conducted the first randomized controlled trial comparing quit rates between HTPs and ECs among people who smoke and do not intend to quit.</p> <p><strong>Methods: </strong>We conducted a 12-week randomized noninferiority switching trial to compare effectiveness, tolerability, and product satisfaction between HTPs (IQOS 2.4 Plus) and refillable ECs (JustFog Q16) among people who do not intend to quit. The cessation intervention included motivational counseling. The primary endpoint of the study was the carbon monoxide-confirmed continuous abstinence rate from week 4 to week 12 (CAR weeks 4-12). The secondary endpoints included the continuous self-reported ≥50% reduction in cigarette consumption rate (continuous reduction rate) from week 4 to week 12 (CRR weeks 4-12) and 7-day point prevalence of smoking abstinence.</p> <p><strong>Results: </strong>A total of 211 participants completed the study. High quit rates (CAR weeks 4-12) of 39.1% (43/110) and 30.8% (33/107) were observed for IQOS-HTP and JustFog-EC, respectively. The between-group difference for the CAR weeks 4-12 was not significant (P=.20). The CRR weeks 4-12 values for IQOS-HTP and JustFog-EC were 46.4% (51/110) and 39.3% (42/107), respectively, and the between-group difference was not significant (P=.24). At week 12, the 7-day point prevalence of smoking abstinence values for IQOS-HTP and JustFog-EC were 54.5% (60/110) and 41.1% (44/107), respectively. The most frequent adverse events were cough and reduced physical fitness. Both study products elicited a moderately pleasant user experience, and the between-group difference was not significant. A clinically relevant improvement in exercise tolerance was observed after switching to the combustion-free products under investigation. Risk perception for conventional cigarettes was consistently higher than that for the combustion-free study products under investigation.</p> <p><strong>Conclusions: </strong>Switching to HTPs elicited a marked reduction in cigarette consumption among people who smoke and do not intend to quit, which was comparable to refillable ECs. User experience and risk perception were similar between the HTPs and ECs under investigation. HTPs may be a useful addition to the arsenal of reduced-risk alternatives for tobacco cigarettes and may contribute to smoking cessation. However, longer follow-up studies are required to confirm significant and prolonged abstinence from smoking and to determine whether our results can be generalized outside smoking cessation services offering high levels of support.</p>
The Effect of a Six Week Intensified Pharmacological Treatment for Major Depressive Disorder Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treat
ClinicalTrials.gov study NCT05973851. IPD Sharing: YES. Countries: 6. Publications: 0.
Effect of Zinc Supplementation on Hyperhomocysteinemia Compared to Folic Acid in CKD Patient on Hemodialysis
ClinicalTrials.gov study NCT06847139. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.