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1,274 results for “Disease Model”

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geo16/100

Imbalanced gut microbiota drives nonalcoholic fatty liver disease and nonalcoholic steatohepatitis in a fast-food diet mouse model

GEO Series GSE190982. Mus musculus. 67 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenApr 2023View details →
geo16/100

CD8+ T cell response in the Act-mOVA/OT-I model of acute graft versus host disease

GEO Series GSE79083. Mus musculus. 24 samples. Type: Expression profiling by array.

openGEO-OpenMar 2019View details →
geo16/100

Study of Molecular and Transcriptomic Age-related Changes in the Dorsal and Ventral Areas of Hippocampus in the 5xFAD Mouse Model of Alzheimer’s Disease

GEO Series GSE302153. Mus musculus. 32 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJul 2025View details →
geo16/100

pH modulation restores proteostasis and extend lifespan in a yeast model of Huntington’s Disease [polyQ]

GEO Series GSE297008. Saccharomyces cerevisiae. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2025View details →
geo16/100

Determining the impact of anti-IL6 and anti-OSM on macrophage and fibroblast biology in a model of fibrotic lung disease [NGS3341]

GEO Series GSE262966. Mus musculus. 25 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2026View details →
geo16/100

Targeting the cGAS–STING Pathway Mitigates Huntington Disease Pathogenesis in a Knock-In Mouse Model

GEO Series GSE313178. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2025View details →
geo16/100

Transcriptional reprogramming by SPI1 (PU.1) modulates Alzheimer’s disease phenotypes in mouse models 

GEO Series GSE225669. Mus musculus. 12 samples. Type: Expression profiling by array.

openGEO-OpenMar 2024View details →
geo16/100

Intermittent fasting reduces alpha-synuclein pathology and functional decline in a mouse model of Parkinson’s disease [sham]

GEO Series GSE252873. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2025View details →
geo16/100

Immune Receptor Lag3 Deletion Alleviates Neurodegeneration Phenotypes in a Mouse Model of Alzheimer’s Disease

GEO Series GSE307127. Mus musculus. 36 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2025View details →
geo16/100

A novel Menin-MLL inhibitor induces specific chromatin changes and eradicates disease in models of MLL-rearranged leukemia

GEO Series GSE127298. Homo sapiens. 224 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2019View details →
geo16/100

A pigtailed macaque model for Kyasanur Forest disease virus and Alkhurma hemorrhagic disease virus pathogenesis

GEO Series GSE185797. Macaca nemestrina. 30 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2021View details →
geo16/100

Multicellular liver organoid model for recapitulating hepatitis C virus infection and non-alcoholic fatty liver disease progression [RNA-Seq]

GEO Series GSE229596. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMay 2024View details →
geo16/100

Comprehensive gene expression analysis of Huntington disease model mouse brains using Transcriptome Tomography

GEO Series GSE228206. Mus musculus. 85 samples. Type: Expression profiling by array.

openGEO-OpenDec 2025View details →
geo16/100

Single-cell transcriptomics revealed molecular vulnerability in a human midbrain-like organoid model of Parkinson's Disease [MERFISH]

GEO Series GSE271118. synthetic construct; Homo sapiens. 21 samples. Type: Other.

openGEO-OpenDec 2025View details →
geo16/100

Urine stem cells as a bona fide model to study cartilage associated disease [RNA-Seq]

GEO Series GSE306729. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2025View details →
geo16/100

Analysis of striatal zinc finger protein (ZFP) repression of mutant Huntingtin (HTT) in the zQ175DN knock-in mouse model of Huntington's disease (bulk RNA-seq)

GEO Series GSE270727. Mus musculus. 233 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJul 2024View details →
geo16/100

Integrated insight into the molecular mechanisms of selenium modulates MPP+ induced cytotoxicity in Parkinson’s disease model

GEO Series GSE186702. Rattus norvegicus. 9 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2024View details →
geo16/100

Designed macrocyclic peptide rescues behavioral impairment and brain pathology in an Alzheimer’s disease mouse model

GEO Series GSE246244. Mus musculus. 71 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2025View details →
geo16/100

Fecal microbiota transfer from autoimmune dry eye disease model mice to conventional mice induces ocular surface inflammation and stereotypic B cell receptor repertoire development in lacrimal gland

GEO Series GSE263577. Mus musculus. 48 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJun 2024View details →
geo16/100

Adult Stem Cell-derived Complete Lung Organoid Models Emulate Lung Disease in COVID-19

GEO Series GSE165200. Homo sapiens. 33 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2021View details →

ScienceDex guides

Understand access before you commit

These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

Compare curated datasets

Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record