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1,174
datasets available to search
ShareScore release 0.7.1
Dataset results
1,174 results for “cancer genomics”
EZH2 inhibition results in genome-wide PRC2 redistribution in cancer cell models
GEO Series GSE134136. Homo sapiens. 44 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Genome-wide perturbations by miRNA map onto functional cancer pathways identifying regulators of chromatin modifiers
GEO Series GSE64020. Homo sapiens. 11 samples. Type: Expression profiling by array.
Proteogenomic characterization and comprehensive integrative genomic analysis of human colorectal cancer liver metastasis
GEO Series GSE93286. Homo sapiens. 6 samples. Type: SNP genotyping by SNP array.
Consticted migration is associated with stable 3D genome structure differences in cancer cells (ATAC-Seq)
GEO Series GSE143674. Homo sapiens. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Whole genome tiling path array CGH analysis of segmental copy number alterations in cervical cancer cells
GEO Series GSE5049. Homo sapiens. 8 samples. Type: Genome variation profiling by genome tiling array.
3D genome of CD8+ T cells reveals IRF8-mediated exhaustion in cancer [Hi-C]
GEO Series GSE299305. Mus musculus. 4 samples. Type: Other.
Drug screening and genomic analyses of HER2 positive breast cancer cell lines reveal predictors for treatment response [Expression profiling]
GEO Series GSE58700. Homo sapiens. 13 samples. Type: Expression profiling by array.
Genome-wide bisulfite sequencing (Xmal-RRBS) of 50 breast cancer samples for jointly using with NGS and chromosomal microarray data
GEO Series GSE190126. Homo sapiens. 50 samples. Type: Methylation profiling by high throughput sequencing.
Genome-wide mRNA profile of human gastric normal and gastric cancer tissues
GEO Series GSE146996. Homo sapiens. 65 samples. Type: Expression profiling by array.
Identification of genomic features that uniquely impact estrogen receptor alpha binding and its effects on gene expression in endometrial cancer
GEO Series GSE312906. Homo sapiens. 12 samples. Type: Other; Genome binding/occupancy profiling by high throughput sequencing.
Genomic Evaluation of Multiparametric Magnetic Resonance Imaging -visible and -nonvisible Lesions in Clinically Localized Prostate Cancer
GEO Series GSE101908. Homo sapiens. 42 samples. Type: Methylation profiling by genome tiling array.
Targeting SUMOylation dependency in human cancer stem cells through a unique SAE2 motif revealed by chemical genomics
GEO Series GSE160551. Homo sapiens. 4 samples. Type: Expression profiling by array.
Implementing whole genome array for clinical use in academic centers: A randomized trial comparing neoadjuvant standard chemotherapy to genomic-driven chemotherapy in operable breast cancer (REMAGUS04
GEO Series GSE63471. Homo sapiens. 142 samples. Type: Expression profiling by array.
Dataset related to article "CRISPR Genome-Wide screening reveals chemosensor receptors as lipid-detecting regulators of macrophage functions in cancer"
<p>This record contains raw data related to article "CRISPR Genome-Wide screening reveals chemosensor receptors as lipid-detecting regulators of macrophage functions in cancer"</p> <p><strong><span>Abstract</span></strong><span>: </span></p> <p><span>The infiltration of macrophages is considered a hallmark of cancer progression and re-education of tumor-associated macrophages towards an anti-tumour status is considered a promising strategy of cancer immunotherapy. However, the mechanisms governing macrophage education by cancer cells remain largely elusive, posing challenges for therapeutic exploitation. To gain deeper insights into TAMs' plasticity, we conducted an unbiased genome-wide CRISPR screening on primary macrophages. Our investigation confirmed the role of known regulators, including Stat6, in orchestrating TAMs' responses and unveiled novel insights into TAMs' behaviour. We identified olfactory and vomeronasal receptors, commonly referred to as chemosensors, as major drivers of macrophages tumor-supportive status in multiple cancers. Collectively, our findings implicate chemosensors in macrophage sensing of the lipid-enriched milieu and highlight these receptors as therapeutic targets for enhancing antitumor immunity.</span></p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.