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129
datasets available to search
ShareScore release 0.9.0
Dataset results
129 results for “Gain-of-Function”
Gain-of-function MUC5B Promoter Variant, Strongly Linked to Idiopathic Pulmonary Fibrosis, Defines an Epigenetically Poised Enhancer (PRO-seq)
GEO Series GSE156541. Homo sapiens. 6 samples. Type: Other.
Differential expression of miR-4520a associated with gain-of-function mutations in Familial Mediterranean Fever (FMF)
GEO Series GSE79954. Homo sapiens; synthetic construct. 10 samples. Type: Non-coding RNA profiling by array.
Neuroligin-3 R451C Induces Gain-of-Function Gene Expression in Astroglia in an Astroglia-Enriched Brain Organoid Model
GEO Series GSE283484. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
A gain-of-function single nucleotide variant creates a new promoter which acts as an orientation-dependent enhancer-blocker
GEO Series GSE159875. Homo sapiens. 165 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other.
A Study to Assess Efficacy and Safety of Oral Tazemetostat in Adult Participants With Relapsed/Refractory Follicular Lymphoma That Does Not Have an "EZH2 Gain-of-function" Genetic Mutation
ClinicalTrials.gov study NCT06068881. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Sex and mutation specific p53 gain-of-function activity in gliomagenesis
GEO Series GSE188710. Mus musculus. 54 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
A human STAT3 gain-of-function variant confers T cell dysregulation without predominant Treg dysfunction in mice
GEO Series GSE207936. Homo sapiens; Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing.
Gain-of-Function p53 Protein Transferred via Small Extracellular Vesicles Promotes Conversion of Fibroblasts to a Cancer-Associated Phenotype [microarray]
GEO Series GSE164248. Homo sapiens. 6 samples. Type: Expression profiling by array.
Single nuclei RNA sequencing of mouse dorsal root, nodose, and trigeminal ganglia from humanized JAK1 gain-of-function mice
GEO Series GSE193435. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Radioresistant Cells in STING Gain-of-function Mice Initiate Lymphocyte-dependent Lung Inflammation and IFNγ-dependent Mortality
GEO Series GSE196342. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Transcritpomic analyses of CARD14 WT and psoriatic gain-of-function CARD14 E138A mutant over time
GEO Series GSE200493. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
18S rRNA N6-methyladenosine (m6A) modification promotes tumorigenesis and chemoresistance via gain-of-function mutant p53 in nasopharyngeal carcinoma
GEO Series GSE186485. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing; Other.
TMPRSS2-ERG and gain-of-function p53 mutants co-dictate pyrimidine synthesis and prostate cancer fitness [RNA-seq-2021 ERG-p53 project]
GEO Series GSE184625. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
The gene expression profile of CD4 T-cells with STAT3 gain-of-function and loss-of-function mutations
GEO Series GSE198963. Homo sapiens. 29 samples. Type: Expression profiling by high throughput sequencing.
TMPRSS2-ERG and gain-of-function p53 mutants co-dictate pyrimidine synthesis and prostate cancer fitness
GEO Series GSE184626. Mus musculus; Homo sapiens. 28 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Gene expression profiling of Dermal Papilla (DP) cells isolated from wild type (WT) and DP-specific Smo gain-of-function (Smo*) mutant mice during both telogen (at P20) and anagen (at P28).
GEO Series GSE115649. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
A Zebrafish JAK1-A634D Gain-of-Function Model Provides New Insights into the Pathogenesis of Familial Hypereosinophilia
GEO Series GSE142599. Danio rerio. 18 samples. Type: Expression profiling by high throughput sequencing.
TMPRSS2-ERG and gain-of-function p53 mutants co-dictate pyrimidine synthesis and prostate cancer fitness [RNA-seq-2018 ERG-p53 project]
GEO Series GSE184624. Mus musculus. 11 samples. Type: Expression profiling by high throughput sequencing.
Gene expression affected by loss-of- or gain-of-function of Dmrt3/Dmrta2 in the dorsomedial telencephalon
GEO Series GSE83639. Mus musculus. 12 samples. Type: Expression profiling by array.
Gain-of-function PPM1D mutations attenuate ischemic stroke
GEO Series GSE295060. Mus musculus. 2 samples. Type: Other.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.