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201
datasets available to search
ShareScore release 0.9.0
Dataset results
201 results for “Glutamate”
Signal transduction-dependent small regulatory RNA is involved in glutamate metabolism of the human pathogen Bordetella pertussis
GEO Series GSE113382. Bordetella pertussis. 6 samples. Type: Expression profiling by array.
Alpha-synuclein overexpression is associated with epigenomic dysregulation of glutamate signaling and locomotor pathways
GEO Series GSE181126. Homo sapiens. 46 samples. Type: Methylation profiling by genome tiling array.
GLUD1 determines murine muscle stem cell fate by controlling mitochondrial glutamate levels
GEO Series GSE243640. Mus musculus. 19 samples. Type: Expression profiling by high throughput sequencing.
Membralin deficiency dysregulates astrocytic glutamate homeostasis leading to ALS-like impairment
GEO Series GSE130763. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
Evidence for glutamate excitotoxicity that occurs before the onset of striatal cell loss and motor symptoms in an ovine Huntington’s Disease model.
GEO Series GSE229839. Ovis aries. 7 samples. Type: Expression profiling by high throughput sequencing.
Carboxypeptidase of glutamate-like gene as a tumor suppressor in pancreatic cancer cells and a prognostic marker for resected pancreatic cancer patients
GEO Series GSE28732. Homo sapiens. 44 samples. Type: Genome variation profiling by array.
Glutamate dehydrogenase (GdhA) of S. pneumoniae is required for high temperature adaptation
GEO Series GSE154888. Streptococcus pneumoniae D39. 8 samples. Type: Expression profiling by array.
Identification of a Subpopulation of Astrocyte Progenitor Cells in the Neonatal Subventricular Zone: Evidence that Migration is Regulated by Glutamate Signaling
GEO Series GSE273223. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment [2]
GEO Series GSE251836. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
A global transcription study of the regulatory effects of potassium, glutamate and c-di-AMP in Bacillus subtilis
GEO Series GSE156738. Bacillus subtilis subsp. subtilis str. 168. 12 samples. Type: Expression profiling by array.
Proline Glutamic acid and Leucine rich Protein 1 (PELP1) promotes glioblastoma progression by enhancing Wnt/β-catenin signaling
GEO Series GSE131502. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Lysine Crotonylation Acts as an Epigenetic Switch for Glutamate Neurotransmission and Spatial Memory
GEO Series GSE281007. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Cytoplasmic Localization of Proline, Glutamic Acid, Leucine-rich Protein 1 (PELP1) Induces Breast Epithelial Cell Migration through Up-regulation of Inhibitor of κB Kinase ϵ and Inflammatory Cross-tal
GEO Series GSE81447. Homo sapiens. 6 samples. Type: Expression profiling by array.
Aging-induced tRNAGlu-derived fragment impairs glutamate biosynthesis by targeting mitochondrial translation-dependent cristae organization
GEO Series GSE183181. Mus musculus. 6 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Data from: Molecular determinants of agonist selectivity in glutamate-gated chloride channels which likely explain the agonist selectivity of the vertebrate glycine and GABAA-ρ receptors
Orthologous Cys-loop glutamate-gated chloride channels (GluClR's) have been cloned and described electrophysiologically and pharmacologically in arthropods and nematodes (both members of the invertebrate ecdysozoan superphylum). Recently, GluClR's from Aplysia californica (a mollusc from the lophotrochozoan superphylum) have been cloned and similarly studied. In spite of sharing a common function, the ecdysozoan and lophotrochozoan receptors have been shown by phylogenetic analyses to have evolved independently. The recent crystallization of the GluClR from C. elegans revealed the binding pocket of the nematode receptor. An alignment of the protein sequences of the nematode and molluscan GluClRs showed that the Aplysia receptor does not contain all of the residues defining the binding mode of the ecdysozoan receptor. That the two receptors have slightly different binding modes is not surprising since earlier electrophysiological and pharmacological experiments had suggested that they were differentially responsive to certain agonists. Knowledge of the structure of the C. elegans GluClR has permitted us to generate a homology model of the binding pocket of the Aplysia receptor. We have analyzed the differences between the two binding modes and evaluated the relative significance of their non-common residues. We have compared the GluClRs electrophysiologically and pharmacologically and we have used site-directed mutagenesis on both receptor types to test predictions made from the model. Finally, we propose an explanation derived from the model for why the nematode receptors are gated only by glutamate, whereas the molluscan receptors can also be activated by β-alanine, GABA and taurine. Like the Aplysia receptor, the vertebrate glycine and GABAA-ρ receptors also respond to these other agonists. An alignment of the sequences of the molluscan and vertebrate receptors shows that the reasons we have given for the ability of the other agonists to activate the Aplysia receptor also explain the agonist profile seen in the glycine and GABAA-ρ receptors.
Dataset for "A Family of Di-Glutamate Mucin Degrading Enzymes that Bridges Glycan Hydrolases and Peptidases"
<p>This dataset provides the classical and QM/MM MD simulation trajectory data to the manuscript:</p><p><strong>A Family of Di-Glutamate Mucin Degrading Enzymes that Bridges Glycan Hydrolases and Peptidases</strong></p><p>The data set contains classical MD simulations of HC7 with substrate peptides, thermodynamics integration (TI) simulations, as well as QM/MM OPES-explore simulations for our manuscript. PDB files for Figure 4f and Figure S21 are also included. A high resolution pdf file of Figure S28 is included, too.</p>
Glutamate Modulation of tDCS Over Premotor Cortex Combined With Peripheral Nerve Stimulation Promoted Observation-execution-related Cortical Excitability and Motor Learning
ClinicalTrials.gov study NCT06694909. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The Effects of Vilazodone on Glutamate in the Anterior Cingulate Cortex in Anxious Unipolar Depressives
ClinicalTrials.gov study NCT02028026. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Role of Antibodies Against Glutamate Receptors and Double Stranded DNA in Epilepsy Patients
ClinicalTrials.gov study NCT00317668. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Long-term Follow-up of Glutamic Acid Decarboxylase (GAD) Gene Transfer in Parkinson's Disease
ClinicalTrials.gov study NCT05894343. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.