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176
datasets available to search
ShareScore release 0.9.0
Dataset results
176 results for “Multidrug resistance”
Changes in Gene Expression Profiling and Phenotype in Aged Multidrug Resistance Protein 4-Deficient Mouse Retina
GEO Series GSE162376. Mus musculus. 8 samples. Type: Expression profiling by array.
Global gene expression profiling and antibiotic susceptibility after repeated exposure to the carbon monoxide-releasing molecule-2 (CORM-2) in multidrug-resistant ESBL-producing uropathogenic Escheric
GEO Series GSE87627. Escherichia coli O157:H7 str. Sakai; Escherichia coli CFT073; Escherichia coli; Escherichia coli O157:H7 str. EDL933; Escherichia coli str. K-12 substr. MG1655. 16 samples. Type: Expression profiling by array.
Genome-wide identification of small RNAs expressed in multidrug-resistant Enterococcus faecium and their implications in daptomycin resistance
GEO Series GSE94924. Enterococcus faecium Aus0004. 4 samples. Type: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing.
Individual multidrug resistance patterns in AML patients point to the need for personalized molecular analysis
GEO Series GSE33787. Homo sapiens. 22 samples. Type: Expression profiling by RT-PCR.
Interplay between acetylation and ubiquitination of Isw1 confers multidrug resistance in Cryptococcus neoformans
GEO Series GSE217187. Cryptococcus neoformans H99. 6 samples. Type: Expression profiling by high throughput sequencing.
Overcoming ABCB1 mediated multidrug resistance in castration resistant prostate cancer
GEO Series GSE271075. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Bruton’s tyrosine kinase inhibition re-sensitizes multidrug-resistant DLBCL tumors to venetoclax
GEO Series GSE267421. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
TGF-β Family Signaling Promotes CDK7 Inhibitor Resistance in Triple Negative Breast Cancer Cells through Upregulation of Multidrug Transporters
GEO Series GSE175727. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Clinical Relevance of Multidrug Resistance Gene Expression in Ovarian Serous Carcinoma Effusions
GEO Series GSE29702. Homo sapiens. 32 samples. Type: Expression profiling by RT-PCR.
Inhibiting Fungal Multidrug Resistance by Disrupting an Activator-Mediator Interaction With the Small Molecule iKIX1
GEO Series GSE74361. Saccharomyces cerevisiae; Nakaseomyces glabratus. 24 samples. Type: Expression profiling by high throughput sequencing.
Mechanisms of multidrug resistance caused by an Ipi1 mutation in the fungal pathogen Candida glabrata
GEO Series GSE255839. Nakaseomyces glabratus. 12 samples. Type: Expression profiling by high throughput sequencing.
Interplay between acetylation and ubiquitination of Isw1 confers multidrug resistance in Cryptococcus neoformans
GEO Series GSE235148. Cryptococcus neoformans. 6 samples. Type: Expression profiling by high throughput sequencing.
Tepoxalin increases chemotherapy efficacy in drug-resistant breast cancer cells overexpressing the multidrug transporter gene ABCB1
GEO Series GSE173411. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Data from: Biofilm-associated multidrug-resistant and methicillin-resistant staphylococcus aureus infections in children
<p><strong>Introduction: </strong>The ability of <em>Staphylococcus aureus</em> to form biofilms—architectural complexes that cause chronic and recalcitrant infections—along with its notorious variant, methicillin-resistant <em>S. aureus</em> (MRSA), leads to multidrug-resistant (MDR) infections that are challenging to treat with antibiotics. This cross-sectional study investigated the prevalence of <em>S. aureus </em>infections in children (<17 years) and characterized the antibiograms of MDR, MRSA, and biofilm-forming strains, along with their coexistence.</p> <p><strong>Methods:</strong> <em>S. aureus</em> strains were isolated and identified from clinical samples and tested for antibiograms following standard microbiology guidelines. MDR strains were non-susceptible to at least one agent in three antimicrobial categories, whereas MRSA strains were cefoxitin-resistant. The gold-standard microtiter plate method was used to detect biofilms. Statistical analyses were performed using SPSS version 17.0.</p> <p><strong>Results:</strong> <em>S. aureus</em> was detected in 9.02% of 543 samples, primarily from pus (79.59%, 39/49). Children aged 1 to <3 years most commonly contracted infections (30.61%, 15/49), and males (67.35%, 33/49) had twice as many infections as females (32.65%, 16/49). As high as 84.69% (83/98) of strains were penicillin-resistant, while 18.37% (27/147) were aminoglycoside-resistant. MDR accounted for 79.59% (39/49) of all <em>S. aureus</em> infections, while MRSA and biofilm-formers accounted for 67.35% (33/49) and 24.49% (12/49), respectively. Fluoroquinolone resistance in non-(MDR-MRSA-biofilm-formers), MDR-MRSA, MDR-biofilm-formers, and MRSA-biofilm-formers was 31.25%, 46.77%, 58.33%, and 60%, respectively, while aminoglycoside resistance was 0%, 32.26%, 50.0%, and 45.0%, and penicillin resistance was 87.50%, 85.48%, 100.0%, and 100.0%.</p> <p><strong>Conclusion:</strong> <em>S. aureus</em>, mostly MDR and MRSA, caused four-fifths of infections in children. Compared to MDR-MRSA and non-(MDR-MRSA-biofilm-formers), MDR-biofilm-formers and MRSA-biofilm-formers triggered higher levels of antimicrobial resistance.</p>
Multidrug Resistance Genes in Patients With Acute Myeloid Leukemia
ClinicalTrials.gov study NCT00898456. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Effectiveness of a Simplified Short Regimen for Multidrug Resistant Tuberculosis in Uzbekistan
ClinicalTrials.gov study NCT02496572. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Utilizing the Crosstalk Among Chicoric Acid, 13-Cis Retinoic Acid(Aerosolized), Minocycline and Vitamin D as a Potent Quadrate Therapy for Treating Patients With Multidrug-resistant TB and Patient Wit
ClinicalTrials.gov study NCT05077813. IPD Sharing: Not stated. Countries: 2. Publications: 0.
Predictive Score in Patients With Hematological Malignancies Colonized by Multidrug-resistant Enterobacteriaceae
ClinicalTrials.gov study NCT07396571. IPD Sharing: NO. Countries: 1. Publications: 0.
Use of Aaerosol Combined With Intravenous Antibiotics for the Treatment of Multidrug Resistant GNB Pneumonia
ClinicalTrials.gov study NCT03921645. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Efficacy and Tolerability of an Antiretroviral Bi-Therapy in HIV Infected Patients With Multidrug Resistance
ClinicalTrials.gov study NCT00120783. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.