Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
341
datasets available to search
ShareScore release 0.9.0
Dataset results
341 results for “Neurodegeneration”
Neuronal ABCA7 deficiency aggravates mitochondrial dysfunction and neurodegeneration in Alzheimer’s disease
GEO Series GSE291086. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
Neurons burdened by DNA double strand breaks incite microglia activation through antiviral-like signaling in neurodegeneration.
GEO Series GSE174265. Mus musculus. 47 samples. Type: Expression profiling by high throughput sequencing; Other.
Integrated stress response associated with dark microglia contributes to neurodegeneration [snRNA-seq]
GEO Series GSE263682. Mus musculus. 3 samples. Type: Expression profiling by high throughput sequencing.
Altered lipid homeostasis underlies selective neurodegeneration in SNX14 deficiency [1 yr]
GEO Series GSE215832. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
CSF1R inhibition rescues tau pathology and neurodegeneration in an A/T/N model with combined AD pathologies, while preserving plaque associated microglia
GEO Series GSE176032. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
ACSS2 upregulation enhances neuronal resilience to aging and neurodegeneration [RNA-seq]
GEO Series GSE254996. Mus musculus. 98 samples. Type: Expression profiling by high throughput sequencing.
Loss of Uhrf1 in neural stem cells leads to activation of retroviral elements and delayed neurodegeneration
GEO Series GSE84550. Mus musculus. 27 samples. Type: Methylation profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
cGAS/STING drives ageing-related inflammation and neurodegeneration
GEO Series GSE234422. Homo sapiens; Mus musculus. 38 samples. Type: Expression profiling by high throughput sequencing.
Gene expression profiling of the AD11 anti-NGF transgenic mouse model of neurodegeneration at 1, 3, 6, 15 months of age
GEO Series GSE63617. Mus musculus. 119 samples. Type: Expression profiling by array.
TGS1 controls snRNA 3' end processing, prevents neurodegeneration and ameliorates SMN-dependent neurological phenotypes in vivo (Nanopore)
GEO Series GSE189138. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Transcriptional characterization of iPSC-derived microglia as a model for therapeutic development in neurodegeneration [Bulk RNA-seq]
GEO Series GSE226076. Homo sapiens. 35 samples. Type: Expression profiling by high throughput sequencing.
A TDP-43 acetylation-mimic mutation that disrupts RNA-binding drives FTLD-like neurodegeneration in a mouse model of sporadic TDP-43 proteinopathy
GEO Series GSE216294. Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing.
A novel hydrogel-based instructive biohybrid 3D culture system for modeling human neural stem cell plasticity, neurogenesis, neurodevelopment, and neurodegeneration
GEO Series GSE78117. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
Extensive cryptic splicing upon loss of RBM17 and TDP43 in neurodegeneration models
GEO Series GSE79020. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Reactivation of mTOR signaling slows neurodegeneration in a lysosomal storage disease
GEO Series GSE275408. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
LINE-1 retrotransposition in a mouse TDP-43 model of neurodegeneration marks motor cortex neurons for cell-intrinsic and cell non-autonomous programmed cell death.
GEO Series GSE300423. Mus musculus. 45 samples. Type: Expression profiling by high throughput sequencing.
Spatial distribution and chromatin accessibility determine the therapeutic capacity of microglial subsets during neurodegeneration [scRNAseq1_LPS_ABX]
GEO Series GSE296026. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
N6-methyladenosine regulates RNA metabolism and neurodegeneration in C9ORF72-ALS/FTD [seq_polyA_RNA-decay]
GEO Series GSE203579. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
Senescent astrocytes derived from human pluripotent stem cells reveal age-related changes and implications for neurodegeneration
GEO Series GSE246073. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Bi-directional regulation between circadian rhythm and neurodegeneration-associated FUS
GEO Series GSE77572. Rattus norvegicus. 35 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.