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308
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ShareScore release 0.9.0
Dataset results
308 results for “Respiratory function”
IUGR, Respiratory Muscle Function, and Exercise Capacity in Childhood
ClinicalTrials.gov study NCT03368755. IPD Sharing: NO. Countries: 1. Publications: 10.
Data from: Reproduction does not adversely affect liver mitochondrial respiratory function but results in lipid peroxidation and increased antioxidants in house mice
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Data from: Respiratory syncytial virus co-opts host mitochondrial function to favour infectious virus production
Although respiratory syncytial virus (RSV) is responsible for more human deaths each year than influenza, its pathogenic mechanisms are poorly understood. Here high-resolution quantitative imaging, bioenergetics measurements and mitochondrial membrane potential- and redox-sensitive dyes are used to define RSV's impact on host mitochondria for the first time, delineating RSV-induced microtubule/dynein-dependent mitochondrial perinuclear clustering, and translocation towards the microtubule-organizing centre. These changes are concomitant with impaired mitochondrial respiration, loss of mitochondrial membrane potential and increased production of mitochondrial reactive oxygen species (ROS). Strikingly, agents that target microtubule integrity the dynein motor protein, or inhibit mitochondrial ROS production strongly suppresses RSV virus production, including in a mouse model with concomitantly reduced virus-induced lung inflammation. The results establish RSV's unique ability to co-opt host cell mitochondria to facilitate viral infection, revealing the RSV-mitochondrial interface for the first time as a viable target for therapeutic intervention.
Dataset related to the poster entitled "Vitamin D3 deficiency disturbed immune response and respiratory function in the murine model of hypersensitivity pneumonitis"
<p><strong>The dataset contains the results presented on a poster presented at the European Academy of Allergy and Clinical Immunology Hybrid Congress, 31 May – 3 June 2024, Valencia, Spain<br><br></strong></p> <p><em>Project title</em><strong>:</strong> "Assessment of the possibility of using vitamin D3 in the prevention and treatment of pulmonary fibrosis in the course of hypersensitivity pneumonitis - <em>in vivo</em> studies"</p> <p><em>Founder</em><strong>: </strong>National Scientific Center, Poland</p> <p><em>Project number</em><strong>:</strong> UMO-2020/38/E/NZ7/00366</p> <p><em>Principal Investigator</em>: Marta Kinga Lemieszek</p> <p><em>Main investigators:</em><strong> </strong>Michał Chojnacki, Ilona Leśniowska, Jakub Anisiewicz</p> <p><em>Place of project implementation</em><strong>:</strong> Department of Medical Biology, Institute of Rural Health, Jaczewskiego 2, 20-090 Lublin, Poland</p>
Behavioral Activation-Rehabilitation to Improve Depressive Symptoms & Physical Function After Acute Respiratory Failure
ClinicalTrials.gov study NCT03431493. IPD Sharing: NO. Countries: 1. Publications: 0.
Dynamic Respiratory Muscle Function in Late-Onset Pompe Disease
ClinicalTrials.gov study NCT02354664. IPD Sharing: NO. Countries: 1. Publications: 0.
Impact of Dyspnea, Regional Lung Ventilation, and Diaphragmatic Function During de Novo Acute Respiratory Failure
ClinicalTrials.gov study NCT04961437. IPD Sharing: NO. Countries: 1. Publications: 0.
Effects of Walking and Respiratory Muscle Training on Pulmonary Function and Functional Exercise Capacity in PD
ClinicalTrials.gov study NCT04834258. IPD Sharing: Not stated. Countries: 0. Publications: 7.
The Effect of Intravenous Lipids on Lung Function in Acute Respiratory Distress Syndrome (ARDS)
ClinicalTrials.gov study NCT01096771. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Epidural Analgesia and Postoperative Respiratory Functions (EPAPRES)
ClinicalTrials.gov study NCT03643757. IPD Sharing: YES. Countries: 0. Publications: 3.
The Effects of Ballet-Based Exercise Training on Respiratory Functions, Balance, Cognitive Functions, Peripheral Muscle Strength, Functional Capacity and Quality of Life in Patients With Parkinson's D
ClinicalTrials.gov study NCT06986941. IPD Sharing: NO. Countries: 0. Publications: 2.
The Effects Of Bronchodilator Therapy On Respiratory And Autonomic Function In Patients With Familial Dysautonomia
ClinicalTrials.gov study NCT01987219. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The Effect of Cow Milk Consumption on Respiratory Symptoms and Pulmonary Functions in Asthmatic and Non Asthmatic Children
ClinicalTrials.gov study NCT02745899. IPD Sharing: NO. Countries: 0. Publications: 1.
Longitudinal Ultrasound Assessment of Diaphragmatic and Respiratory Muscle Function Following Respiratory Muscle Training in Frail Older Adults
ClinicalTrials.gov study NCT07258615. IPD Sharing: UNDECIDED. Countries: 0. Publications: 0.
Respiratory Capacity and Swallowing Function in Spinal Disorders: A Pilot Study
ClinicalTrials.gov study NCT04114604. IPD Sharing: NO. Countries: 1. Publications: 0.
Respiratory Function and Walking Capacity in Multiple Sclerosis
ClinicalTrials.gov study NCT01774201. IPD Sharing: NO. Countries: 0. Publications: 2.
Maintain Respiratory Muscle Function and Reduce Pneumonia Risk in Cancer Patients
ClinicalTrials.gov study NCT03469271. IPD Sharing: NO. Countries: 1. Publications: 0.
Influence of an Inspiratory Muscle Fatigue Protocol on Older Adults on Respiratory Muscle Strength, Muscle Oxygen Saturation, and Functional Capacity
ClinicalTrials.gov study NCT06266013. IPD Sharing: UNDECIDED. Countries: 0. Publications: 1.
Effect of Respiratory Exercises With Pelvic Floor Rehab on Dyspareunia & Autonomic Function in Women
ClinicalTrials.gov study NCT07078318. IPD Sharing: YES. Countries: 0. Publications: 7.
Data from: Respiratory syncytial virus co-opts host mitochondrial function to favour infectious virus production
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.