Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
122
datasets available to search
ShareScore release 0.9.0
Dataset results
122 results for “T-cell responses”
A Prospective Observational Cohort Study on Dynamic CD8+ T-cell Profiling and Multi-omics Biomarkers for Predicting Conversion Therapy Response in Unresectable Hepatocellular Carcinoma
ClinicalTrials.gov study NCT07117279. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Self-reactivity of CD8 T-cell clones determines their differentiation status rather than their responsiveness in infections
GEO Series GSE208795. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing; Other.
Transcriptional state of T-cells from Atm-proficient and Atm-deficient mice in response to B-cell lymphoma
GEO Series GSE136773. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
Stimulation of oncogene-specific tumor infiltrating T-cells through combined vaccine and alpha-PD1 enable sustained anti-tumor responses against established HER2 breast cancer (BC) [WXS]
GEO Series GSE148478. Mus musculus. 20 samples. Type: Genome variation profiling by high throughput sequencing.
Stimulation of oncogene-specific tumor infiltrating T-cells through combined vaccine and alpha-PD1 enable sustained anti-tumor responses against established HER2 breast cancer (BC) [RNA-Seq]
GEO Series GSE148477. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
Stimulation of oncogene-specific tumor infiltrating T-cells through combined vaccine and alpha-PD1 enable sustained anti-tumor responses against established HER2 breast cancer (BC)
GEO Series GSE148482. Mus musculus. 70 samples. Type: Expression profiling by high throughput sequencing; Genome variation profiling by high throughput sequencing.
Partially exhausted CD8+ T cells are associated with clinically beneficial response to Teplizumab in new onset type I diabetes (single-cell RNA-seq of sorted CD8+ T-cells)
GEO Series GSE85527. Homo sapiens. 219 samples. Type: Expression profiling by high throughput sequencing.
Partially exhausted CD8+ T cells are associated with clinically beneficial response to Teplizumab in new onset type I diabetes (bulk RNA-seq of sorted CD8+ T-cells)
GEO Series GSE85530. Homo sapiens. 63 samples. Type: Expression profiling by high throughput sequencing.
NOTCH1 signaling during CD4+ T-cell activation alters transcription factor networks and enhances antigen responsiveness [CULTURED_NCT07]
GEO Series GSE207314. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
Stimulation of oncogene-specific tumor infiltrating T-cells through combined vaccine and alpha-PD1 enable sustained anti-tumor responses against established HER2 breast cancer (BC) [scRNA-Seq]
GEO Series GSE148480. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
T-cell responses to a specific antigen
GEO Series GSE214174. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
LCK-deficient CD8 T-cell show reduced proliferation but normal effector responses in vivo
GEO Series GSE304760. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing; Other.
Early dendritic cell molecular signature modelling predicts late vaccine-induced adaptive T-cell responses (Codelink)
GEO Series GSE66930. Mus musculus. 113 samples. Type: Expression profiling by array.
Early dendritic cell molecular signature modelling predicts late vaccine-induced adaptive T-cell responses (Illumina)
GEO Series GSE66797. Mus musculus. 117 samples. Type: Expression profiling by array.
Type-I Interferon drives T-cell responses to Amyloid-beta in the central nervous system
GEO Series GSE280018. Mus musculus. 24 samples. Type: Other.
Type I interferon responses mediated by CD14⁺ monocytes drive CD4⁺ T-cell activation in PWH
GEO Series GSE317465. Homo sapiens. 24 samples. Type: Expression profiling by array.
Gene expression data from T-cell progenitors developing in response to DLL4 stimulation in the plastic thymus
GEO Series GSE46191. Mus musculus. 4 samples. Type: Expression profiling by array.
Virtual memory T-cells orchestrate extra-lymphoid responses conducive to resident memory
GEO Series GSE148364. Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing.
T-cell receptor/CD28-targeted Immunotherapeutics Generate Functional Melanoma- or HIV-specific Responses by Selectively Driving Naïve T-Cell Expansion
GEO Series GSE286286. Homo sapiens. 22 samples. Type: Other.
Link to dataset related to article "mRNA COVID-19 vaccine booster fosters B- and T-cell responses in immunocompromised patients"
<p>This record contains raw data related to article “mRNA COVID-19 vaccine booster fosters B- and T-cell responses in immunocompromised patients"</p> <p>SARS-CoV-2 vaccination has proven effective in inducing an immune response in healthy individuals and is progressively us allowing to overcome the pandemic. Recent evidence has shown that response to vaccination in some vulnerable patients may be diminished, and it has been proposed a booster dose. We tested the kinetic of development of serum antibodies to the SARS-CoV-2 Spike protein, their neutralizing capacity, the CD4 and CD8 IFN-γ T-cell response in 328 subjects, including 131 immunocompromised individuals (cancer, rheumatologic, and hemodialysis patients), 160 health-care workers (HCW) and 37 subjects older than 75 yr, after vaccination with two or three doses of mRNA vaccines. We stratified the patients according to the type of treatment. We found that immunocompromised patients, depending on the type of treatment, poorly respond to SARS-CoV-2 mRNA vaccines. However, an additional booster dose of vaccine induced a good immune response in almost all of the patients except those receiving anti-CD20 antibody. Similarly to HCW, previously infected and vaccinated immunocompromised individuals demonstrate a stronger SARS-CoV-2-specific immune response than those who are vaccinated without prior infection.</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.