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147 results for “Telomere Length”
Full data on telomere length and lifespan
<p>Telomeres are protective caps at the end of eukaryotic chromosomes that shorten with age and in response to stressful or resource-demanding conditions. Their length predicts individual health and lifespan across a wide range of animals, but whether the observed positive association between telomere length and lifespan is environmentally induced, or set at conception due to a shared genetic basis, has not been tested in wild animals. We applied quantitative genetic 'animal models' to longitudinal telomere measurements collected over a 10-year period from individuals of a wild seabird (common tern; <i>Sterna hirundo</i>) with known pedigree. We found no variation in telomere shortening with age among individuals at the phenotypic and genetic level, and only a small permanent environmental effect on adult telomere length. Instead, we found telomere length to be highly heritable and strongly positively genetically correlated with lifespan. Such heritable differences between individuals that are set at conception may present a <i>hitherto</i> underappreciated component of variation in somatic state.</p>
Early maternal separation is not associated with changes in telomere length in domestic kittens (Felis catus)
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Data from: Telomere length reflects phenotypic quality and costs of reproduction in a long-lived seabird
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Early‐life seasonal, weather and social effects on telomere length in a wild mammal
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Data from: Maternal telomere length inheritance in the king penguin
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Data from: Links between parental life histories of wild salmon and the telomere lengths of their offspring
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Data from: Increasing the accuracy and precision of relative telomere length estimates by RT qPCR
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Data from: Primers to highly conserved elements optimized for qPCR-based telomere length measurements in vertebrates
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Data from: Intergenerational effects on offspring telomere length; interactions among maternal age, stress exposure and offspring sex
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Data from: Sex differences in leucocyte telomere length in a free-living mammal
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Data from: Reduced telomere length in offspring of old fathers in a long-lived seabird
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Data from: Shorter juvenile telomere length is associated with higher survival to spawning in migratory Atlantic salmon
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Data from: Is telomere length a molecular marker of individual quality? insights from a long-lived bird
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Data from: Age-related declines in immune response in a wild mammal are unrelated to immune cell telomere length
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Full data on telomere length and lifespan
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Telomere Length Protects Mice from Human Disease Phenotype Caused By Notch1 Haploinsufficiency
GEO Series GSE83963. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing.
LONG-TERM EFFECTS OF BCG VACCINATION ON TELOMERE LENGTH AND TELOMERASE ACTIVITY
GEO Series GSE300272. Homo sapiens. 20 samples. Type: Expression profiling by high throughput sequencing.
Investigating the role of telomere length in 3D spatiotemporal gene regulation in cardiomyocytes [RNA-Seq]
GEO Series GSE217701. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Telomere heterogeneity linked to metabolism and pluripotency state revealed by simultaneous measurement of telomere length and RNA-seq in the same human ES cell
GEO Series GSE98644. Homo sapiens. 121 samples. Type: Expression profiling by high throughput sequencing.
Semimethylation is a feature of Diffuse Large B-cell Lymphoma, and subgroups with poor prognosis are characterized by global hypomethylation and short telomere length
GEO Series GSE255869. Homo sapiens. 97 samples. Type: Methylation profiling by array.
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Allen Brain Atlas
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Annotated Behaviour and Observability Dataset (ABODe)
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The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
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