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Dataset results
137 results for “aspergillus fumigatus”
Transcriptome response of Aspergillus fumigatus cultures under different temperatures
GEO Series GSE16617. Aspergillus fumigatus. 3 samples. Type: Expression profiling by array.
Stress responses elicited by glucose withdrawal in Aspergillus fumigatus
GEO Series GSE216000. Aspergillus fumigatus. 12 samples. Type: Expression profiling by high throughput sequencing.
The oxidative stress response highly depends on glucose and iron availability in Aspergillus fumigatus
GEO Series GSE256524. Aspergillus fumigatus. 24 samples. Type: Expression profiling by high throughput sequencing.
mRNA-seq of Aspergillus fumigatus RNAi double knockouts
GEO Series GSE223618. Aspergillus fumigatus. 36 samples. Type: Expression profiling by high throughput sequencing.
5' poly(A)-RNA-End sequencing of Aspergillus fumigatus strain CEA10
GEO Series GSE296591. Aspergillus fumigatus. 6 samples. Type: Other.
Aspergillus fumigatus ZnfA, a novel zinc finger transcription factor involved in calcium metabolism and caspofungin tolerance
GEO Series GSE167847. Aspergillus fumigatus. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
3' poly(A)-RNA-End sequencing of Aspergillus fumigatus strain CEA10
GEO Series GSE296592. Aspergillus fumigatus. 8 samples. Type: Other.
Genome-wide transcriptional changes under oxidative stress in iron-starved Aspergillus fumigatus cultures
GEO Series GSE94818. Aspergillus fumigatus. 12 samples. Type: Expression profiling by high throughput sequencing.
RNA-seq analysis of AtrR-regulated gene expression in Aspergillus fumigatus cells in response to voriconazole.
GEO Series GSE267651. Aspergillus fumigatus. 21 samples. Type: Expression profiling by high throughput sequencing.
Effect of Artemisinin on Aspergillus fumigatus gene expression program
GEO Series GSE21297. Aspergillus fumigatus. 2 samples. Type: Expression profiling by array.
Microbial Observatory (ISS-MO): Draft Genome Sequence of two Aspergillus fumigatus Strains Isolated from the International Space Station
Aspergillus fumigatus is a saprophytic, filamentous fungus that is ubiquitous outdoors (soil, decaying vegetation) and indoors (hospitals, simulated closed habitats, etc.). A. fumigatus can adapt to various environmental conditions and form airborne conidia that are the inoculum for a variety of diseases (e.g. non- and invasive pulmonary infections, allergic bronchopulmonary aspergillosis, etc.) in immunocompromised hosts. In an on-going Microbial Observatory Experiments on the International Space Station (ISS) molecular phylogeny of several fungal isolates were characterized. Two strains, ISSF 21 and IF1SW-F4, were isolated from the HEPA filter and the surface of the Cupola of the ISS, respectively. Using primers targeting the internal transcribed spacers ITS1 and 2, both isolates were identified as A. fumigatus. The whole genome sequence analysis of ISSF 21 revealed increased number of single nucleotide polymorphisms (SNPs) when compared to the reference A. fumigatus 293. Knowing that A. fumigatus is an opportunistic pathogen and microgravity highly influences the antibiotic susceptibility and pathogenicity of microorganisms, we examined pathogenicity of both ISS isolates using the zebrafish larval model. The space station isolates (ISSF-021 and IF1SW-F4) were more virulent than two clinical strains (Af293 and CEA10) whose pathogenicity was highly characterized. Here the whole genome sequences of ISSF-021 strain are being deposited.
Proteomic characterization of Aspergillus fumigatus isolated from air and surfaces of the International Space Station
The on-going Microbial Observatory Experiments on the International Space Station (ISS) revealed the presence of various microorganisms that may be affected by the distinct environment of the ISS. The low-nutrient environment combined with enhanced irradiation and microgravity may trigger changes in the molecular suit of microorganisms leading to increased virulence and resistance of microbes. Proteomic characterization of two Aspergillus fumigatus strains, ISSFT-021 and IF1SW-F4, isolated from HEPA filter debris and cupola surface of the ISS, respectively, is presented, along with a comparison to experimentally established clinical isolates Af293 and CEA10. In-depth analysis highlights variations in the proteome of both ISS-isolated strains when compared to the clinical strains. Proteins up-regulated in ISS isolates were involved in oxidative stress response, and carbohydrate and secondary metabolism. This report provides insight into possible molecular adaptation of filamentous fungi to the unique ISS environment. Lastly, an attempt was made to elucidate plausible causes of the enhanced virulence of both ISS-isolated A. fumigatus strains.
tRF & tiRNA sequencing of Aspergillus fumigatus
GEO Series GSE267453. Aspergillus fumigatus. 9 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Histone acetyl transferase (HAT) and APSES TF of Aspergillus fumigatus
GEO Series GSE182799. Aspergillus fumigatus Af293. 15 samples. Type: Expression profiling by high throughput sequencing.
sRNA-seq of Aspergillus fumigatus RNAi double knockouts
GEO Series GSE267454. Aspergillus fumigatus. 36 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Transcriptomics analysis of Aspergillus fumigatus co-cultivated with Pseudomonas aeruginosa
GEO Series GSE122391. Aspergillus fumigatus A1163; Pseudomonas aeruginosa PAO1. 27 samples. Type: Expression profiling by high throughput sequencing.
RNA-seq of limmmunocompetent mice in response to Aspergillus fumigatus conidia and hyphae
GEO Series GSE183979. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Role of squalene hopene cyclase in azole-resistance and virulence of Aspergillus fumigatus
GEO Series GSE317610. Aspergillus fumigatus. 12 samples. Type: Expression profiling by high throughput sequencing.
Transcriptional profile of ΔcalA and ΔcrzA Aspergillus fumigatus mutants during mammal infection
GEO Series GSE27428. Aspergillus fumigatus Af293; Aspergillus fumigatus. 6 samples. Type: Expression profiling by array.
Loss of pulmonary tissue protection promotes severe Aspergillus fumigatus infection during Influenza A Virus
GEO Series GSE276049. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.