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823
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Dataset results
823 results for “kRas”
Dataset I related to publication: Binding modes of the KRAS(G12C) inhibitors GDC-6036 and LY3537982 revealed by all atom molecular dynamics simulations
<p>Dataset related to publication:<em> </em></p> <p><em>Leini, R., Kapp, J., Kopra, K. et al. Binding modes of the KRAS(G12C) inhibitors GDC-6036 and LY3537982 revealed by all atom molecular dynamics simulations. Sci Rep <strong>15</strong>, 24843 (2025). https://doi.org/10.1038/s41598-025-07532-2</em></p> <ul> <li>.zip-files contain the raw Desmond trajectories of individual replica simulations of GDC-6036.</li> <li>WaterMap-output file for the representative conformation of GDC-6036.</li> </ul>
Dataset II related to publication: Binding modes of the KRAS(G12C) inhibitors GDC-6036 and LY3537982 revealed by all atom molecular dynamics simulations
<p>Dataset related to publication:<em> </em></p> <p>Leini, R., Kapp, J., Kopra, K. <em>et al.</em> Binding modes of the KRAS(G12C) inhibitors GDC-6036 and LY3537982 revealed by all atom molecular dynamics simulations. <em>Sci Rep</em> <strong>15</strong>, 24843 (2025). https://doi.org/10.1038/s41598-025-07532-2</p> <ul> <li>.zip-files contain the raw Desmond trajectories of individual replica simulations of LY3537982.</li> <li>WaterMap-output file for the representative conformation of LY3537982</li> </ul>
Binimetinib and Palbociclib or TAS-102 in Treating Patients With KRAS and NRAS Mutant Metastatic or Unresectable Colorectal Cancer
ClinicalTrials.gov study NCT03981614. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Study of JDQ443 in Comparison With Docetaxel in Participants With Locally Advanced or Metastatic KRAS G12C Mutant Non-small Cell Lung Cancer
ClinicalTrials.gov study NCT05132075. IPD Sharing: YES. Countries: 25. Publications: 0.
A Study Of PF-05212384 Plus Irinotecan Vs Cetuximab Plus Irinotecan In Patients With KRAS And NRAS Wild Type Metastatic Colorectal Cancer
ClinicalTrials.gov study NCT01925274. IPD Sharing: YES. Countries: 4. Publications: 0.
VIC-1911 Monotherapy in Combination With Sotorasib for the Treatment of KRAS G12C-Mutant Non-Small Cell Lung Cancer
ClinicalTrials.gov study NCT05374538. IPD Sharing: NO. Countries: 1. Publications: 0.
A Study of BMS-986466 With Adagrasib With or Without Cetuximab in Participants With Kirsten Rat Sarcoma Virus Glycine 12 to Cysteine (KRAS G12C)-Mutant Solid Tumors
ClinicalTrials.gov study NCT06024174. IPD Sharing: YES. Countries: 5. Publications: 0.
Cetuximab Plus Biweekly Capecitabine and Oxaliplatin in KRAS Wild Type Metastatic Colorectal Cancer
ClinicalTrials.gov study NCT00444678. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Tarlox and Sotorasib in Patients With KRAS G12C Mutations
ClinicalTrials.gov study NCT05313009. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Study of CMAB009 to Treat KRAS Wild Type Metastatic Colorectal Cancer
ClinicalTrials.gov study NCT01550055. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Study Evaluating the Safety and Efficacy of FOLFIRI Plus Cetuximab or FOLFOX Plus Cetuximab as First-line Therapy in Subjects With KRAS Wild-type Metastatic Colorectal Cancer (APEC-Study)
ClinicalTrials.gov study NCT00778830. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Clinical And Translational Study Of MK-2206 In Patients With Metastatic KRAS-Wild-Type, PIK3CA-Mutated, Colorectal Cancer
ClinicalTrials.gov study NCT01186705. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Phase 2 Study of TVB-2640 in KRAS Non-Small Cell Lung Carcinomas
ClinicalTrials.gov study NCT03808558. IPD Sharing: NO. Countries: 1. Publications: 0.
NKTR-102 Versus Irinotecan in Patients With Second-Line, Irinotecan-Naïve, KRAS Mutant, Colorectal Cancer
ClinicalTrials.gov study NCT00856375. IPD Sharing: Not stated. Countries: 6. Publications: 0.
A First-in-human Study of BGB-53038, a Pan-KRAS Inhibitor, Alone or in Combinations in Participants With Advanced or Metastatic Solid Tumors With KRAS Mutations or Amplification
ClinicalTrials.gov study NCT06585488. IPD Sharing: YES. Countries: 6. Publications: 0.
A Study of Sotorasib (AMG 510) in Participants With Stage IV NSCLC Whose Tumors Harbor a KRAS p.G12C Mutation in Need of First-line Treatment
ClinicalTrials.gov study NCT04933695. IPD Sharing: YES. Countries: 10. Publications: 0.
Regorafenib and Methotrexate in Treating Participants With Recurrent or Metastatic KRAS Mutated Non-Small Cell Lung Cancer
ClinicalTrials.gov study NCT03520842. IPD Sharing: NO. Countries: 1. Publications: 0.
HRS-4642 in Combination With Nimotuzumab and Chemotherapy for BRPC With KRAS G12D Mutation
ClinicalTrials.gov study NCT07240766. IPD Sharing: NO. Countries: 1. Publications: 0.
A Study of Repotrectinib in Combination With Other Anticancer Therapies for the Treatment of Subjects With KRAS-Mutant Solid Tumors
ClinicalTrials.gov study NCT05071183. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Platform Study of JDQ443 in Combinations in Patients With Advanced Solid Tumors Harboring the KRAS G12C Mutation
ClinicalTrials.gov study NCT05358249. IPD Sharing: YES. Countries: 8. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.