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ShareScore release 0.9.0
Dataset results
236 results for “motor learning”
Influence of Arousal on Motor Learning, Memory and Motor Imagery Ability in Young Population
ClinicalTrials.gov study NCT04911439. IPD Sharing: Not stated. Countries: 2. Publications: 7.
Data from: Coupling between motor cortex and striatum increases during sleep over long-term skill learning
Open the record for dataset details and reuse information.
Data from: Substance P signalling in primary motor cortex facilitates motor learning in rats
Among the genes that are up-regulated in response to a reaching training in rats, Tachykinin 1 (Tac1) - a gene that encodes the neuropeptide Substance P (Sub P) - shows an especially strong expression. Using Real-Time RT-PCR, a detailed time-course of Tac1 expression could be defined: a significant peak occurs 7 hours after training ended at the first and second training session, whereas no up-regulation could be detected at a later time-point (sixth training session). To assess the physiological role of Sub P during movement acquisition, microinjections into the primary motor cortex (M1) contralateral to the trained paw were performed. When Sub P was injected before the first three sessions of a reaching training, effectiveness of motor learning became significantly increased. Injections at a time-point when rats already knew the task (i.e. training session ten and eleven) had no effect on reaching performance. Sub P injections did not influence the improvement of performance within a single training session, but retention of performance between sessions became strengthened at a very early stage (i.e. between baseline-training and first training session). Thus, Sub P facilitates motor learning in the very early phase of skill acquisition by supporting memory consolidation. In line with these findings, learning related expression of the precursor Tac1 occurs at early but not at later time-points during reaching training.
Closed-loop auditory stimulation method to modulate sleep slow waves and motor learning performance in rats
<p>Slow waves and cognitive output have been modulated in humans by phase-targeted auditory stimulation. However, to advance its technical development and further our understanding, implementation of the method in animal models is indispensable. Here, we report the successful employment of slow waves' phase-targeted closed-loop auditory stimulation (CLAS) in rats. To validate this new tool both conceptually and functionally, we tested the effects of up- and down‑phase CLAS on proportions and spectral characteristics of sleep, and on learning performance in the single pellet‑reaching task, respectively. Without affecting 24-h sleep-wake behavior, CLAS specifically altered delta (slow waves) and sigma (sleep spindles) power persistently over chronic periods of stimulation. While up-phase CLAS does not elicit a significant change in behavioral performance, down-phase CLAS exerted a detrimental effect on overall engagement and success rate in the behavioral test. Overall CLAS-dependent spectral changes were positively correlated with learning performance. Altogether, our results provide proof-of-principle evidence that phase-targeted CLAS of slow waves in rodents is efficient, safe and stable over chronic experimental periods, enabling the use of this high‑specificity tool for basic and preclinical translational sleep research.</p>
Slow oscillation-spindle coupling strength predicts real-life gross-motor learning in adolescents and adults
<p>Previously, we demonstrated that precise temporal coordination between slow oscillations (SO) and sleep spindles indexes declarative memory network development (Hahn et al., 2020). However, it is unclear whether these findings in the declarative memory domain also apply in the motor memory domain. Here, we compared adolescents and adults learning juggling, a real-life gross-motor task. We found that improved task proficiency after sleep lead to an attenuation of the learning curve, suggesting a dynamic juggling learning process. We employed individualized cross-frequency coupling analyses to reduce inter and intra-group variability of oscillatory features. Advancing our previous findings, we identified a more precise SO-spindle coupling in adults compared to adolescents. Importantly, coupling precision over motor areas predicted overnight changes in task proficiency and learning curve, indicating that SO-spindle coupling is sensitive to the dynamic motor learning process. Our results provide first evidence that regionally specific precisely coupled sleep oscillations support gross-motor learning.</p>
Motor Learning in Stroke Patients and Healthy Volunteers
ClinicalTrials.gov study NCT00021710. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Brain Changes Associated With Learning a Motor Task
ClinicalTrials.gov study NCT00076466. IPD Sharing: Not stated. Countries: 1. Publications: 3.
The Effect of Motor Imagery Dosage on Motor Learning in Healthy Adults
ClinicalTrials.gov study NCT06299345. IPD Sharing: YES. Countries: 2. Publications: 0.
Motor Learning Through Virtual Reality Task in Individuals With Down Syndrome
ClinicalTrials.gov study NCT02719600. IPD Sharing: NO. Countries: 0. Publications: 1.
Motor Learning After Cerebellar Damage: The Role of the Primary Motor Cortex
ClinicalTrials.gov study NCT05351255. IPD Sharing: YES. Countries: 1. Publications: 0.
Effect of Aging on Cortical Excitability and Motor Learning
ClinicalTrials.gov study NCT03750903. IPD Sharing: NO. Countries: 1. Publications: 0.
Exercise Program Based on Motor Learning and Forward Head Posture Correction
ClinicalTrials.gov study NCT03006497. IPD Sharing: UNDECIDED. Countries: 0. Publications: 10.
Learning a Motor Task Through Observation
ClinicalTrials.gov study NCT00050869. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Pilot Trial of Remotely-Supervised Transcranial Direct Current Stimulation (RS-tDCS) to Enhance Motor Learning in Progressive Multiple Sclerosis (MS)
ClinicalTrials.gov study NCT03499314. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Motor Skill Learning in People With Parkinson's Disease
ClinicalTrials.gov study NCT00396942. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Cortical Contributions to Motor Sequence Learning
ClinicalTrials.gov study NCT04138953. IPD Sharing: YES. Countries: 1. Publications: 0.
TDCS Effects on Motor Learning and Motor Control in Healthy Subjetcs
ClinicalTrials.gov study NCT03931512. IPD Sharing: YES. Countries: 1. Publications: 0.
Effect of Levodopa on Postural Motor Learning in Parkinson Disease
ClinicalTrials.gov study NCT02239978. IPD Sharing: NO. Countries: 1. Publications: 0.
Cognitive Behavioral Therapy And Motor Learning Technique Among Attention Deficit Hyperactivity Disorder Adults
ClinicalTrials.gov study NCT06064032. IPD Sharing: Not stated. Countries: 0. Publications: 24.
Long-Term Motor Learning in Focal Hand Dystonia
ClinicalTrials.gov study NCT00325091. IPD Sharing: Not stated. Countries: 1. Publications: 3.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.